Samir K. Saha

ORCID: 0000-0003-3820-0748
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About
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Research Areas
  • Pneumonia and Respiratory Infections
  • Salmonella and Campylobacter epidemiology
  • Neonatal and Maternal Infections
  • Respiratory viral infections research
  • Bacterial Infections and Vaccines
  • Viral gastroenteritis research and epidemiology
  • Global Maternal and Child Health
  • Vibrio bacteria research studies
  • Child Nutrition and Water Access
  • Streptococcal Infections and Treatments
  • Antibiotic Resistance in Bacteria
  • Neonatal skin health care
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Semiconductor Quantum Structures and Devices
  • Bacteriophages and microbial interactions
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Hepatitis Viruses Studies and Epidemiology
  • Vaccine Coverage and Hesitancy
  • Sepsis Diagnosis and Treatment
  • Influenza Virus Research Studies
  • Pancreatic function and diabetes
  • Bacterial Identification and Susceptibility Testing
  • Photonic and Optical Devices
  • Neonatal Respiratory Health Research
  • Antibiotics Pharmacokinetics and Efficacy

Child Health Research Foundation
2016-2025

Dhaka Shishu Hospital
2015-2024

International Centre for Diarrhoeal Disease Research
2005-2024

University of Arkansas at Fayetteville
2018-2023

State University of Bangladesh
2023

World Health Organization
2016-2022

Institute of Post Graduate Medical Education and Research
2021

West Bengal State University
2012-2021

Human Development Research Foundation
2020

Save the Children
2005-2016

We aimed to provide the first comprehensive estimates of burden group B Streptococcus (GBS), including invasive disease in pregnant and postpartum women, fetal infection/stillbirth, infants. Intrapartum antibiotic prophylaxis is current mainstay prevention, reducing early-onset infant high-income contexts. Maternal GBS vaccines are development.For 2015 live births, we used a compartmental model estimate (1) exposure maternal colonization, (2) cases disease, (3) deaths, (4) disabilities....

10.1093/cid/cix664 article EN cc-by Clinical Infectious Diseases 2017-07-26

Abstract Background Urinary tract infection (UTI) in pregnancy, including asymptomatic bacteriuria, is associated with maternal morbidity and adverse pregnancy outcomes, preterm birth low birthweight. In low-middle income countries (LMICs), the capacity for screening treatment of UTIs limited. The objective this study was to describe population-based prevalence, risk factors, etiology antimicrobial resistance patterns Bangladesh. Methods a community-based cohort Sylhet district, Bangladesh,...

10.1186/s12884-019-2665-0 article EN cc-by BMC Pregnancy and Childbirth 2019-12-31
Stephanie W. Lo Rebecca A. Gladstone Andries J. van Tonder John A. Lees Mignon du Plessis and 84 more Rachel Benisty Noga Givon‐Lavi Paulina A. Hawkins Jennifer Cornick Brenda Kwambana-Adams Pierra Y. Law Pak‐Leung Ho Martín Antonio Dean Everett Ron Dagan Anne von Gottberg Keith P. Klugman Lesley McGee Robert F. Breiman Stephen D. Bentley Abdullah Brooks Alejandra Corso Alexander Davydov Alison J. Maguire Andrew J. Pollard Anmol Kiran Anna Skoczyńska Benild Moiane Bernard Beall Betuel Sigaúque David M. Aanensen Deborah Lehmann Diego Faccone Ebenezer Foster-Nyarko Ebrima Bojang Egorova Ea Е. А. Воропаева Eric Sampane-Donkor Ewa Sadowy Godfrey Bigogo Hélio Mucavele Houria Belabbès Idrissa Diawara Jennifer C. Moïsi Jennifer R. Verani Jeremy D. Keenan Jyothish Bhai Kedibone Ndlangisa Khalid Zerouali K L Ravikumar Leonid Titov Linda de Gouveia Maaike Alaerts Margaret Ip Maria Cristina de Cunto Brandileone Md Hasanuzzaman Metka Paragi Michele Nurse-Lucas Mushal Ali Naima Elmdaghri Nicholas J. Croucher Nicole Wolter Nurit Porat Özgen Köseoğlu Eser Patrick Eberechi Akpaka Paul Turner Paula Gagetti Peggy-Estelle Tientcheu Philip E. Carter Rafal Mostowy Rama Kandasamy Rebecca Ford Rebecca Henderson Roly Malaker Sadia Shakoor Samanta Cristine Grassi Almeida Samir K. Saha Sanjay Doiphode Shabir A. Madhi Shamala Devi Sekaran Somporn Srifuengfung Stephen Obaro Stuart C. Clarke Susan Nzenze Tamara Kastrin Theresa J. Ochoa Balaji Veeraraghavan Waleria Hryniewicz Yulia Urban

Invasive pneumococcal disease remains an important health priority owing to increasing incidence caused by pneumococci expressing non-vaccine serotypes. We previously defined 621 Global Pneumococcal Sequence Clusters (GPSCs) analysing 20 027 isolates collected worldwide and from published genomic data. In this study, we aimed investigate the lineages behind predominant serotypes, mechanism of serotype replacement in disease, as well major contributing invasive post-vaccine era their...

10.1016/s1473-3099(19)30297-x article EN cc-by The Lancet Infectious Diseases 2019-06-10

More than 500 000 neonatal deaths per year result from possible serious bacterial infections (pSBIs), but the causes are largely unknown. We investigated incidence of community-acquired caused by specific organisms among neonates in south Asia.From 2011 to 2014, we identified babies through population-based pregnancy surveillance at five sites Bangladesh, India, and Pakistan. Babies were visited home community health workers up ten times age 0 59 days. Illness meeting WHO definition pSBI...

10.1016/s0140-6736(18)31127-9 article EN cc-by The Lancet 2018-07-01

Background There is limited data on antibiotic treatment in hospitalized neonates low- and middle-income countries (LMICs). We aimed to describe patterns of use, pathogens, clinical outcomes, develop a severity score predicting mortality neonatal sepsis inform future trial design. Methods findings Hospitalized infants <60 days with were enrolled during 2018 2020 by 19 sites 11 (mainly Asia Africa). Prospective daily observational was collected signs, supportive care, treatment,...

10.1371/journal.pmed.1004179 article EN cc-by PLoS Medicine 2023-06-08

The emergence of increasingly antimicrobial-resistant Salmonella enterica serovar Typhi (S Typhi) threatens to undermine effective treatment and control. Understanding where antimicrobial resistance in S is emerging spreading crucial towards formulating control strategies.In this genomic epidemiology study, we sequenced the genomes 3489 strains isolated from prospective enteric fever surveillance studies Nepal, Bangladesh, Pakistan, India (between 2014 2019), combined these with a global...

10.1016/s2666-5247(22)00093-3 article EN cc-by The Lancet Microbe 2022-06-21

Enteric fever, a systemic infection caused by Salmonella enterica serovars Typhi and Paratyphi A, remains major cause of morbidity mortality in low-income middle-income countries. fever is preventable through the provision clean water adequate sanitation can be successfully treated with antibiotics. However, high levels antimicrobial resistance (AMR) compromise effectiveness treatment. We provide estimates prevalence AMR S A 75 endemic countries, including 30 locations without data.

10.1016/s2214-109x(23)00585-5 article EN cc-by The Lancet Global Health 2024-02-15

Terpenes and terpenoids are primary constituents of essential oils different type plants owers.Some qualitative estimation methods in plant tissue have been previously described but there is no protocol estimating the same quantitatively till date.In present study a has attempted to estimate total concentration resin producing using monoterpene, Linalool as standard reagent.

10.1038/protex.2012.055 article EN cc-by-nc Protocol Exchange 2012-11-27

Pneumonia, the leading infectious cause of child mortality globally, mainly afflicts developing countries. This prospective observational study aimed to assess microorganisms associated with pneumonia in children aged <5 years and emerging A multicenter, case-control by GABRIEL (Global Approach Biological Research, Infectious diseases Epidemics Low-income countries) network was conducted between 2010 2014 Cambodia, China, Haiti, India (2 sites), Madagascar, Mali, Mongolia, Paraguay. Cases...

10.1093/cid/cix378 article EN Clinical Infectious Diseases 2017-05-02

With the rise in fluoroquinolone-resistant Salmonella Typhi and recent emergence of ceftriaxone resistance, azithromycin is one last oral drugs available against typhoid for which resistance uncommon. Its increasing use, specifically light ongoing outbreak extensively drug-resistant (XDR) (resistant to chloramphenicol, ampicillin, cotrimoxazole, streptomycin, fluoroquinolones third-generation cephalosporins) Pakistan, places selective pressure spread azithromycin-resistant isolates. However,...

10.1371/journal.pntd.0007868 article EN cc-by PLoS neglected tropical diseases 2019-11-15
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