Jason R. Andrews
A5079007877- Tuberculosis Research and Epidemiology
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
- Vibrio bacteria research studies
- COVID-19 Clinical Research Studies
- Mycobacterium research and diagnosis
- Parasites and Host Interactions
- COVID-19 epidemiological studies
- Global Maternal and Child Health
- Pneumonia and Respiratory Infections
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 detection and testing
- Child Nutrition and Water Access
- Viral Infections and Outbreaks Research
- Diagnosis and treatment of tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Criminal Justice and Corrections Analysis
- Infectious Diseases and Tuberculosis
- Respiratory viral infections research
- Parasite Biology and Host Interactions
- Long-Term Effects of COVID-19
- Antibiotic Resistance in Bacteria
- Bacteriophages and microbial interactions
- Mosquito-borne diseases and control
Stanford University
2016-2025
Stanford Medicine
2016-2024
Institute for Health Metrics and Evaluation
2018-2024
University of Washington
2018-2024
Massachusetts General Hospital
2011-2022
World Health Organization - Pakistan
2022
Sabin Vaccine Institute
2022
Federal Ministry of Health
2022
University of California, Davis
2022
Johns Hopkins University
2022
Based on the clinical and operative findings in sixty-eight knees with acute tears of medial compartment cruciate ligaments, a standardized terminology classification knee ligament instability is presented. With an intact posterior ligament, anteromedial, anterolateral, or posterolateral rotatory may occur, but not true posteromedial instability. ruptured, straight anterior, posterior, medial, lateral be found.
During infectious disease outbreaks, data collected through health institutions and official reporting structures may not be available for weeks, hindering early epidemiologic assessment. By contrast, from informal media are typically in near real-time could provide earlier estimates of epidemic dynamics. We assessed correlation volume cholera-related HealthMap news reports, Twitter postings, government cholera cases reported the first 100 days 2010 Haitian outbreak. Trends sources...
Although a preventable and treatable disease, tuberculosis causes more than million deaths each year. As countries work towards achieving the Sustainable Development Goal (SDG) target to end epidemic by 2030, robust assessments of levels trends burden are crucial inform policy programme decision making. We assessed in fatal non-fatal drug resistance HIV status for 195 territories from 1990 2016.We analysed 15 943 site-years vital registration data, 1710 verbal autopsy 764 sample-based 361...
An understanding of the trends in tuberculosis incidence, prevalence, and mortality is crucial to tracking success control programmes identification remaining challenges. We assessed fatal non-fatal burden over past 25 years for 195 countries territories.
The multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) epidemics are rapidly expanding in South Africa. Our initial report of HIV-associated XDR TB Africa revealed rapid near complete mortality. Lower mortality has been described the literature, but few these patients have HIV coinfected.To characterize from MDR a setting with high HIV-coinfection rates.We conducted retrospective observational study among 654 cases diagnosed Tugela Ferry, Africa, 2005 to 2007....
Severe acute respiratory syndrome coronavirus 2 infections can cause disease 2019 (COVID-19), which manifests with a range of severities from mild illness to life-threatening pneumonia and multi-organ failure. COVID-19 is characterized by an inflammatory signature, including high levels cytokines, alveolar infiltrates vascular microthrombi. Here we show that patients severe produced unique serologic increased likelihood IgG1 afucosylated Fc glycans. This modification on IgGs enhanced...
To estimate the effectiveness of inactivated whole virus vaccine, CoronaVac (Sinovac Biotech), against symptomatic covid-19 in elderly population São Paulo state, Brazil during widespread circulation gamma variant.Test negative case-control study.Community testing for Brazil.43 774 adults aged ≥70 years who were residents state and underwent reverse transcription polymerase chain reaction (RT-PCR) SARS-CoV-2 from 17 January to 29 April 2021. 26 433 cases with 622 test controls symptoms...
Abstract Type III interferons have been touted as promising therapeutics in outpatients with coronavirus disease 2019 (COVID-19). We conducted a randomized, single-blind, placebo-controlled trial (NCT04331899) 120 mild to moderate COVID-19 determine whether single, 180 mcg subcutaneous dose of Peginterferon Lambda-1a (Lambda) within 72 hours diagnosis could shorten the duration viral shedding (primary endpoint) or symptoms (secondary endpoint). In both 60 patients receiving Lambda and...
Abstract The effectiveness of inactivated vaccines (VE) against symptomatic and severe COVID-19 caused by omicron is unknown. We conducted a nationwide, test-negative, case-control study to estimate VE for homologous heterologous (BNT162b2) booster doses in adults who received two CoronaVac Brazil the Omicron context. Analyzing 1,386,544 matched-pairs, disease was 8.6% (95% CI, 5.6–11.5) 56.8% 56.3–57.3) period 8–59 days after receiving booster, respectively. During same interval, Covid-19...
Obesity, characterized by chronic low-grade inflammation of the adipose tissue, is associated with adverse coronavirus disease 2019 (COVID-19) outcomes, yet underlying mechanism unknown. To explore whether severe acute respiratory syndrome 2 (SARS-CoV-2) infection tissue contributes to pathogenesis, we evaluated COVID-19 autopsy cases and deeply profiled response SARS-CoV-2 in vitro. In cases, identified RNA adipocytes an inflammatory infiltrate. We two distinct cellular targets infection: a...
The emergence of increasingly antimicrobial-resistant Salmonella enterica serovar Typhi (S Typhi) threatens to undermine effective treatment and control. Understanding where antimicrobial resistance in S is emerging spreading crucial towards formulating control strategies.In this genomic epidemiology study, we sequenced the genomes 3489 strains isolated from prospective enteric fever surveillance studies Nepal, Bangladesh, Pakistan, India (between 2014 2019), combined these with a global...