Katherine L. O’Brien
A5055802709- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Bacterial Infections and Vaccines
- Pneumocystis jirovecii pneumonia detection and treatment
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Emergency and Acute Care Studies
- Viral gastroenteritis research and epidemiology
- Streptococcal Infections and Treatments
- Wheat and Barley Genetics and Pathology
- Tuberculosis Research and Epidemiology
- Immunodeficiency and Autoimmune Disorders
- SARS-CoV-2 and COVID-19 Research
- Genetics and Plant Breeding
- Antimicrobial Resistance in Staphylococcus
- Viral Infections and Outbreaks Research
- Crop Yield and Soil Fertility
- Viral Infections and Immunology Research
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- Child and Adolescent Health
- Immune responses and vaccinations
- Hepatitis Viruses Studies and Epidemiology
- Cystic Fibrosis Research Advances
- Neonatal and Maternal Infections
Johns Hopkins University
2016-2025
World Health Organization
2008-2024
London School of Hygiene & Tropical Medicine
2024
The University of Queensland
2012-2024
Right to Care
2021
Children's Minnesota
2020-2021
World Health Organization - Pakistan
2021
Royal United Hospital Bath NHS Trust
2021
University of Idaho
2003-2020
Africa Health Research Institute
2019-2020
Potato (Solanum tuberosum L.) is the world's most important non-grain food crop and central to global security. It clonally propagated, highly heterozygous, autotetraploid, suffers acute inbreeding depression. Here we use a homozygous doubled-monoploid potato clone sequence assemble 86% of 844-megabase genome. We predict 39,031 protein-coding genes present evidence for at least two genome duplication events indicative palaeopolyploid origin. As first an asterid, reveals 2,642 specific this...
Rotavirus is a leading cause of childhood gastroenteritis and death worldwide.We studied healthy infants approximately 6 to 12 weeks old who were randomly assigned receive three oral doses live pentavalent human-bovine (WC3 strain) reassortant rotavirus vaccine containing human serotypes G1, G2, G3, G4, P[8] or placebo at 4-to-10-week intervals in blinded fashion. Active surveillance was used identify subjects with serious adverse other events.The 34,035 the group 34,003 monitored for...
Pneumococcal conjugate vaccine (PCV) and Haemophilus influenzae type b (Hib) are now used in most countries. To monitor global regional progress towards improving child health to inform national policies for disease prevention treatment, we prepared global, regional, burden estimates these pathogens children from 2000 2015.Using WHO Maternal Child Epidemiology Estimation collaboration country-specific of pneumonia meningitis mortality morbidity 2015, applied pneumococcal Hib cause-specific...
Pneumonia is the leading cause of death among children younger than 5 years. In this study, we estimated causes pneumonia in young African and Asian children, using novel analytical methods applied to clinical microbiological findings.
In a pooled analysis of data collected from invasive pneumococcal disease surveillance databases, Daniel Feikin and colleagues examine serotype replacement after the introduction 7-valent conjugate vaccine (PCV7) into national immunization programs. Please see later in article for Editors' Summary
The recent series of reviews conducted within the Global Action Plan for Pneumonia and Diarrhoea (GAPPD) addressed epidemiology two deadly diseases at global regional level; it also estimated effectiveness interventions, barriers to achieving high coverage main implications health policy. aim this paper is provide estimates childhood pneumonia country level. This should allow national policy-makers stakeholders implement proposed policies in World Health Organization (WHO) UNICEF member...
In South Africa, a 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in 2009 with three-dose schedule for infants at 6, 14, and 36 weeks of age; 13-valent (PCV13) replaced PCV7 2011. 2012, it estimated that 81% 12-month-old children had received three doses vaccine. We assessed the effect vaccination on invasive disease.We conducted national, active, laboratory-based surveillance disease. calculated change incidence disease from prevaccine (baseline) period (2005 through 2008) to...