A5008977725- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Metal complexes synthesis and properties
- Synthesis of Tetrazole Derivatives
- Organometallic Compounds Synthesis and Characterization
- Click Chemistry and Applications
- Crystal structures of chemical compounds
- Advanced biosensing and bioanalysis techniques
- Antimicrobial agents and applications
- RNA Interference and Gene Delivery
- Computational Drug Discovery Methods
- Radiopharmaceutical Chemistry and Applications
- Corrosion Behavior and Inhibition
- Chalcogenide Semiconductor Thin Films
- Lanthanide and Transition Metal Complexes
- Polyoxometalates: Synthesis and Applications
- Nanocluster Synthesis and Applications
- Organic Light-Emitting Diodes Research
- Iron-based superconductors research
- Advanced Cellulose Research Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Lipid metabolism and biosynthesis
- 2D Materials and Applications
- Wound Healing and Treatments
Monash University
2016-2024
Victoria Police
2024
Curtin University
2011-2023
Australian Regenerative Medicine Institute
2016-2020
Bentley (Canada)
2015
University of Bologna
2014
Bentley University
2014
The synthesis, structural, and photophysical properties of a novel family neutral fac-[Re(N∧N)(CO)3(L)] complexes, where N∧N is either 2,2′-bipyridine or 1,10-phenanthroline L para functionalized 5-aryltetrazolate [namely, 5-phenyltetrazolate (Tph−), 4-(tetrazolate-5-yl)benzaldehyde (Tbdz−), 5-(4-acetylphenyl)tetrazolate (Tacy−), methyl 4-(tetrazolate-5-yl)benzoate (Tmeb−)] are reported. complexes were prepared by direct addition the corresponding tetrazolate anion to acetonitrile solvated...
Neutral Re(<sc>i</sc>) tetrazolato complexes exhibit labeling of lipid droplets with high specificity.
The irreversible reaction of methyl triflate with neutral Re(I) tetrazolato complexes the type fac-[Re(diim)(CO)3(L)], where diim is either 1,10-phenanthroline or 2,2'-bipyridine and L a para substituted 5-aryltetrazolate, yielded corresponding cationic methylated complexes. While methylation occurred regioselectively at N4 position tetrazole ring, were found to exist in solution as equilibrating mixtures linkage isomers, Re(i) centre was bound N1 N2 atom ring. existence these isomers...
Lipids have an important role in many aspects of cell biology, including membrane architecture/compartment formation, intracellular traffic, signalling, hormone regulation, inflammation, energy storage and metabolism. Lipid biology is therefore integrally involved major human diseases, metabolic disorders, neurodegenerative obesity, heart disease, immune disorders cancers, which commonly display altered lipid transport However, the investigation these cellular processes has been limited by...
Optical epifluorescence microscopy was used in conjunction with X-ray fluorescence imaging to monitor the stability and intracellular distribution of luminescent rhenium(i) complex fac-[Re(CO)3(phen)L], where phen = 1,10-phenathroline L 5-(4-iodophenyl)tetrazolato, 22Rv1 cells. The rhenium showed no signs ancillary ligand dissociation, a conclusion based on data obtained via aligning iodine distributions. A diffuse reticular localisation detected for nuclear/perinuclear region cells, by...
Antimicrobial resistance is becoming an ever-increasing threat for human health. Metal complexes and, in particular, those that incorporate bismuth offer attractive alternative to the typically used organic compounds which bacteria are often able develop determinants. Herein we report synthesis, characterization, and biological evaluation of a series homo- heteroleptic bismuth(III) thiolates incorporating either one (BiPh2L), two (BiPhL2), or three (BiL3) sulfur-containing azole ligands...
One of the distinct features metal-tetrazolate complexes is possibility performing electrophilic additions onto imine-type nitrogens coordinated five-membered ring. These reactions, in particular, provide a useful tool for varying main structural and electronic properties starting tetrazolate complexes. In this paper, we demonstrate how use simple protonation-deprotonation protocol enables us to reversibly change, significant extent, light-emission output performance series...
A series of poorly soluble phenyl bis-phosphinato bismuth(III) complexes [BiPh(OP(=O)R1 R2 )2 ] (R1 =R2 =Ph; R1 =p-OMePh; =m-NO2 Ph; =Ph, =H; =Me) have been synthesised and characterised, shown to effective antibacterial activity against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), methicillin-resistant (MRSA) vancomycin-resistant Enterococcus (VRE). The bismuth were incorporated into microfibrillated (nano-) cellulose generating a bismuth-cellulose composite as paper...
Starting from anionic tetrazole-based ligands, namely, 5-(4′-cyanophenyl)tetrazolate and 5-(4′-pyridyl)tetrazolate, mononuclear dinuclear complexes of fac-[Re(CO)3(phen)]+ (phen = 1,10-phenanthroline) were prepared characterized. For the complexes, regioselective coordination metal fragments on negatively charged tetrazolato ring is exclusively obtained. Coordination to benzonitrile pyridine groups was achieved by previous alkylation tetrazole ring. Dinuclear obtained treatment corresponding...
Thioalkyl-functionalised Re(I) tetrazolato complexes highlight good accumulation and lack of photobleaching in live He-La cells.
A series of homoleptic and heteroleptic bismuth(III) flavonolate complexes derived from six flavonols varying substitution have been synthesised structurally characterised. The were evaluated for antibacterial activity towards several problematic Gram-positive (Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE)) Gram-negative (Escherichia coli, Pseudomonas aeruginosa) bacteria. cell viability COS-7 (monkey kidney) cells treated...
Rhenium(I) tricarbonyl complexes are widely studied for their cell imaging properties and anti-cancer anti-microbial activities, but the with S-donor ligands remain relatively unexplored. A series of six
Three new and different homo- hetero-bimetallic polyoxometalate (POM) species have been synthesised by simple one-pot synthetic methods utilising naturally occurring bismite (Bi2O3) (or Bi(NO3)3·5H2O) aryl sulfonic acids. The POM isolated are (NH4)14[Bi2W22O76]·14H2O (1·14H2O), (NH4)[Bi(DMSO)7][Mo8O26]·H2O (2·H2O) [(NH4)4(Mo36O108(OH)4·16H2O)]·45H2O (3·45H2O). compounds characterised X-ray crystallography, energy dispersive spectroscopy (EDX), powdered diffraction (PXRD), mass spectrometry...
The formation of mixed-metal sulfides with the general structure AgBiS2 and Cu3 BiS2 by a simple two-step process utilizing bismuth dithiocarboxylates as Bi S precursors is described. A sonochemical reaction Bi2 O3 six different aryl dithioic acids: dithiobenzoic acid (BDT-H), 4-methoxydithiobenzoic (4-MBDT-H), 3-methyldithiobenzoic (3-MBDT-H), 2-mesitylenedithioic (2-MDT-H), 4-fluorodithiobenzoic (4-FBDT-H), 2-thiophenedithioic (2-TDT-H) resulted in corresponding complexes: [Bi(BDT)3 ] 1,...
Luminescent metal complexes are a valuable platform for the generation of cell imaging agents. However, many cationic, factor that can dominate intracellular accumulation to specific organelles. Neutral Re(I) offer more attractive development bioconjugated agents, where charge cannot influence their distribution. Herein, we report synthesis neutral complex (ReAlkyne), which was used as four carbohydrate-conjugated agents via Cu(I)-catalyzed azide–alkyne cycloaddition. A comprehensive...
Solid-state metathesis (SSM) reactions between Bi(NO3 )3 ⋅5 H2 O and potassium benzene-1,2-disulfonate (=1,2-BDSK2 ), sodium benzene-1,3-disulfonate (=1,3-BDSNa2 ) allows access to the first 2D, {[Bi6 O4 (OH)4 (1-2BDS)2 (NO3 )2 ⋅4 O]⋅11 O}∞ {[Bi22 O24 (OH)6 (1,3-BDS)6 ⋅12 DMSO]⋅3 DMSO⋅4 , 3D, (1,3-BDS)3 O]⋅6 polymeric networks of sulfonato encapsulated polynuclear bismuth oxido/hydroxido clusters.
A series of diphenyl mono-phosphinato bismuth complexes were synthesised to study the effect ligand choice on antibacterial activity, mammalian cell toxicity, and their behaviour in Bi-nanocellulose composites for use as materials.
To study and evaluate the structure-activity relationships in di-aryl bismuth phosphinates on antibacterial activity cytotoxicity a series of complexes containing ortho-methoxyphenyl, meta-methoxyphenyl, meta-tolyl para-tolyl aryl groups; [Bi(o-MeOPh)2(O(O)P(H)Ph)]n1, [Bi(o-MeOPh)2(O(O)PPh2)]n2, [Bi(o-MeOPh)2(O(O)P(p-MeOPh)2)]n3, [Bi(m-MeOPh)2(O(O)P(H)Ph)]n4, [Bi(m-MeOPh)2(O(O)PPh2)]n5, [Bi(m-MeOPh)2(O(O)P(p-MeOPh)2)]n6, [Bi(m-tol)2(O(O)P(H)Ph)]n7, [Bi(m-tol)2(O(O)PPh2)]n8,...
Eight novel bismuth(III) sulfonato compounds have been synthesized and characterized using the sonochemical reaction of Bi2O3 with a range sulfonic acids, including 2,5-dimethylbenzenesulfonic acid (2,5-DMSH), 2,4-dinitrobenzenesulfonic (2,4-DNSH), 2,5-dichlorobenzenesulfonic (2,5-DCSH), 1,2-benzenedisulfonic (1,2-BDSH2), 1,3-benzenedisulfonic (1,3-BDSH2), 2-sulfobenzoic (2-SBH2), 3-sulfobenzoic (3-SBH2), 2-naphthalenesulfonic (NPSH). Six complexes (1, 2, 4, 6-8) were structurally through...