A5101799778- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Cancer Immunotherapy and Biomarkers
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Cancer Cells and Metastasis
- Diverticular Disease and Complications
- Cancer, Hypoxia, and Metabolism
- Cytokine Signaling Pathways and Interactions
- Advanced X-ray and CT Imaging
- Hepatitis B Virus Studies
- Acupuncture Treatment Research Studies
- interferon and immune responses
- Esophageal Cancer Research and Treatment
- Diagnosis and treatment of tuberculosis
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatitis Pathology and Treatment
- Cancer-related gene regulation
- Inflammatory Bowel Disease
- Circular RNAs in diseases
- Renal and related cancers
- MicroRNA in disease regulation
Lishui City People's Hospital
2010-2023
Wenzhou Medical University
2009-2022
INTRODUCTION: Whether 10-day short-course vonoprazan-amoxicillin dual therapy (VA-dual) is noninferior to the standard 14-day bismuth-based quadruple (B-quadruple) against Helicobacter pylori eradication has not been determined. This trial aimed compare rate, adverse events, and compliance of VA-dual regimen with B-quadruple as first-line H. treatment. METHODS: prospective randomized clinical was performed at 3 institutions in eastern China. A total 314 treatment-naive, –infected patients...
Senescent microenvironments play an important role in tumor progression. Here, we report that doxorubicin ( DOX )‐pretreated or replicative senescent stromal cells WI ‐38 and HUVEC ) promote colorectal cancer CRC cell growth invasion vitro vivo . These pro‐tumorigenic effects were attenuated by exogenous administration of Klotho, anti‐aging factor. We subsequently identified several senescence‐associated secretory phenotype SASP )‐associated genes, including CCL 2, which significantly...
Background: The relationship between tumour size and metastasis rate is poorly recognized in patients with pancreatic neuroendocrine tumours (PNETs). impact of on prognosis was controversial previous investigations. Methods: PNETs cases diagnosed from 1988 to 2013 were retrieved the Surveillance, Epidemiology, End Results (SEER) database. Clinicopathologic features retrospectively analyzed. Survival calculated by Kaplan-Meier method. Multivariable Cox regression models hazard ratios (HRs)...
Background. Retinoic acid-inducible gene-I (RIG-I) has crucial effects on various cancers, while RIG-I’s detailed roles and mechanism in colorectal cancer (CRC) are uncovered. Methods. qRT-PCR was used to detect the expression of RIG-I CRC, adjacent nontumor specimens, five cell lines. CCK-8, colony formation, flow cytometry assays were conducted study CRC viabilities. Extracellular acidification rates, lactate analysis, ATP analysis viabilities glucose metabolism cells. Western blot is...
To study the preventive effect of sophocarpine (Soc) on dextran sulfate sodium (DSS)-induced colitis in mice, order to analyze influence Soc toll like receptor 4 (TLR4)/mitogen-activated protein kinases (MAPKs) and janus tyrosine kinase 2 signal transducer activator transcription 3 (JAK2/STAT3) pathways mice intestinal tissues. The was given 2.5% DSS for 6 days induce acute model. Soc-treated group intraperitoneally injected with 30 mg · kg(-1) d(-1) since day before experiment end. disease...
Article Serum neopterin and indoleamine 2,3-dioxyg activity are promising biomarkers for presence progression of hepatitis B was published on January 1, 2022 in the journal Pteridines (volume 33, issue 1).
Objective To explore the diagnostic value of multi-slice computer tomography (MSCT) in cause and location agnogenic intestinal obstruction. Methods With light speed 16 multiple slice spiral-CT, 68 patients clinically suggested obstruction were underwent plain scan second phase enhanced whole abdomen. The image data was post-processed through GEADW4. 4 station with multi-planar reconstruction (MPR) maximum intensity projection (MIP). CT characters analyzed by comparing suggestions operation...
Objective To investigate the esophageal variceal bleeding,mortality,degree of varices and changes liver function in patients with hepatic cirrhosis Who underwent endoscopic varieeal ligation (EVL) or received propranolol therapy.Methods One hundred eighteen either EVL (n=66) therapy(n=52).The group were treated for several times untill varicose vein disappeared.However,the 10 mg twice daily at beginning treatment.and it was increased to maximum tolerated dose gradually.All followed up 20...