A5010495571- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Ovarian cancer diagnosis and treatment
- Lung Cancer Treatments and Mutations
- BRCA gene mutations in cancer
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Cancer Genomics and Diagnostics
- Nutritional Studies and Diet
- Cancer, Lipids, and Metabolism
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- Parathyroid Disorders and Treatments
- Endometrial and Cervical Cancer Treatments
- Cancer Diagnosis and Treatment
- Bone health and treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Radiopharmaceutical Chemistry and Applications
- Dialysis and Renal Disease Management
- Magnesium in Health and Disease
- Cancer Treatment and Pharmacology
- Economic and Financial Impacts of Cancer
- Historical and Contemporary Political Dynamics
- Breast Implant and Reconstruction
- Cancer Immunotherapy and Biomarkers
Amgen (United States)
2013-2023
Johns Hopkins Medicine
2023
Johns Hopkins University
2023
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2015
Lesley University
2014-2015
Exponent (United States)
2009-2014
University of California, San Francisco
2014
Bellevue Hospital Center
2009-2013
Fred Hutch Cancer Center
2007-2013
University of Washington
2011-2013
Patients receiving dialysis undergo parathyroidectomy to improve laboratory parameters in resistant hyperparathyroidism with the assumption that clinical outcomes will also improve. However, no randomized trial data demonstrate benefits of parathyroidectomy. This study aimed evaluate up 1 year after a nationwide sample patients hemodialysis.Using from US Renal Data System, this identified prevalent hemodialysis aged ≥18 years Medicare as primary payers who underwent 2007 2009. Baseline...
Summary Background and objectives Parathyroid hormone, calcium, phosphate have been independently associated with cardiovascular event risk. Because these parameters may be on the same causal pathway proposed as quality measures, an integrated approach to estimating risks is needed. Design, setting, participants, & measurements Prevalent dialysis patients were followed from August 31, 2005 December 2006. A two-stage modeling was used. First, 16-month probabilities of death composite end...
Abstract Objective: To evaluate the effect of ovarian cancer risk on performance serum biomarkers mesothelin, human epididymis protein 4 (HE4), and CA125. Methods: We measured HE4, CA125 levels from women with invasive (n = 143), benign gynecologic conditions 124), controls 344). Demographic, epidemiologic, reproductive, medical, family history data were collected using a standardized questionnaire. Pedigree BRCA 1/2 test results used to stratify into average high-risk groups. The diagnostic...
Abstract BACKGROUND. The current study sought to examine whether an index based on the specific pattern of symptoms commonly reported by women with ovarian cancer could be used in combination CA 125 improve sensitivity or specificity experimental methods screening for cancer. METHODS. A prospective case‐control design was used. Participants included 254 healthy at high risk disease because family history, and 75 Logistic regression analysis determine symptom predicted RESULTS. Symptom...
In Brief OBJECTIVE: To estimate the current effect of demographics, pathology, and treatment on mortality among women with vaginal cancer. METHODS: Using data from 17 population-based cancer registries that participate in Surveillance, Epidemiology, End Results program, 2,149 diagnosed primary between 1990 2004 were identified. The association various demographic factors, tumor characteristics, treatments risk evaluated using Cox proportional hazards modeling. RESULTS: mean age±standard...
Abstract Objective: To evaluate if serum levels of candidate ovarian cancer biomarkers vary with individual characteristics healthy women who are likely candidates for an screening program. Methods: We analyzed CA125, mesothelin, and HE4 in a sample 155 postmenopausal at increased risk developing based on personal family history. Information reproductive, medical histories, lifestyle factors, anthropometry was collected by self-report. Twenty-two factors were examined using univariate...
This study reports the value of tumor markers estrogen receptor (ER), progesterone (PR), and human epidermal growth factor 2 (HER2) in predicting response breast cancer to neoadjuvant chemotherapy. A community center prospectively maintained database containing over 8,000 patient records was used. Since 1989, 464 patients were treated with chemotherapy followed by surgical resection tested for ER PR. Estrogen and/or PR positive considered hormone (HR) positive. Human status available on 368...
Background: Tumors of the metastatic colorectal cancer (mCRC) patients that are wildtype (WT) for KRAS or NRAS mutations respond more favorably to anti-epidermal growth factor receptor (EGFR) treatments. Treatment guidelines now recommend all mCRC have WT and tumor status confirmed prior initiating anti-EGFR therapy. Evidence also suggests BRAF may predict lack response As such, there is a need comprehensive data on prevalence , among with mCRC. Methods: A systematic literature review was...
Little is known about changes in parathyroid hormone (PTH), calcium and phosphorous levels after parathyroidectomy hemodialysis patients. We studied the effects of on these biochemical values a large cohort patients receiving maintenance hemodialysis. This retrospective study included identified both United States Renal Data System database dialysis organization who underwent 2007–09, were aged ≥18 years, had Medicare Parts A B as primary payer received for ≥1 year pre-parathyroidectomy....
Abstract While ovarian cancer is rare and screening not recommended for most women, it being studied as a way to reduce mortality. As effective strategies emerge will be important understand the quality of life (QOL) effects participation in screening. In this study, we examined an program on worry about risk QOL. A randomized controlled clinical trial ( n = 592) was conducted. Women without family history suggestive BRCA1/2 mutation were randomly assigned counseling, separately combination....
BackgroundEvaluating diagnostic and early detection biomarkers requires comparing serum protein concentrations among biosamples ascertained from subjects with without cancer. Efforts are generally made to standardize blood processing storage conditions for cases controls, but sample collection cannot be completely controlled. For example, samples often obtained persons aware of their diagnoses, collected after fasting or in surgery, whereas some controls may different conditions, such as a...
Some ingestible complementary and alternative medicine (CAM) supplements, including herbal remedies, teas, vitamins, have biological activities that make them likely to interact poorly with conventional chemotherapeutic treatments. This study surveyed women ovarian cancer document the extent which use CAM supplements treatments are believed be of potential concern when used together.A total 219 patients who received care from 1 2 participating oncology practices were about during after...