A5053480280- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pancreatic and Hepatic Oncology Research
- Immunotherapy and Immune Responses
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Voice and Speech Disorders
- Circular RNAs in diseases
- Cancer survivorship and care
- RNA modifications and cancer
- Mitochondrial Function and Pathology
- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
First Affiliated Hospital of Jiamusi University
2020-2022
Jiamusi University
2018-2022
Background: To classify triple-negative breast cancer (TNBC) immunotyping using the public database, analyze differences between subtypes in terms of clinical characteristics and explore role significance immune TNBC immunotherapy. Methods: We downloaded data from cBioPortal GEO databases. The genes were grouped to obtain gene modules annotate their biological functions. Log-rank tests Cox regression used evaluate prognosis (IS). Drug sensitivity analysis was also performed for among...
LASP2 was recently demonstrated to serve as multifaceted roles in several types of cancers. However, its underlying mechanism the progression human liver cancer has not been explored. The aims current study were detect expression a tissue microarray, and determine whether contributes malignant phenotypes HepG2 hepatoblastoma cells. Our results revealed that downregulated tissues relative normal non-cancerous tissues, closely correlated with process cancer. In vitro, upregulation by...
Non-coding RNAs such as long non-coding (lncRNAs) and microRNAs (miRNAs) have been found to be indispensable factors in carcinogenesis cancer development. Numerous studies explored the regulatory functions of these molecules identified synergistic interactions among lncRNAs or miRNAs, while those between miRNAs remain investigated. In this study, we constructed characterized an lncRNA-miRNA network following a four-step approach by integrating pairs expression profiles. The with more shared...
This study retrospectively investigated the effect of neuromuscular electrical stimulation (NMES) for fatigue management in patients with advanced laryngeal cancer (ALC) receiving chemoradiotherapy.A total 60 eligible ALC chemoradiotherapy were included. These assigned equally to a treatment group and control group. Patients received NMES therapy treated 8 weeks, while did not receive therapy. The primary outcome was fatigue, measured by multidimensional inventory (MFI). secondary outcomes...