A5100643500- Cancer Cells and Metastasis
- Genetic factors in colorectal cancer
- Cancer-related molecular mechanisms research
- Colorectal Cancer Surgical Treatments
- Liver Diseases and Immunity
- Saffron Plant Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Epigenetics and DNA Methylation
- Thermal Regulation in Medicine
- 3D Printing in Biomedical Research
- Colorectal Cancer Treatments and Studies
- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- RNA Research and Splicing
- Drug Transport and Resistance Mechanisms
- Clinical practice guidelines implementation
- Chemokine receptors and signaling
- Ferroptosis and cancer prognosis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Infrared Thermography in Medicine
- Cancer Immunotherapy and Biomarkers
- Respiratory Support and Mechanisms
- Immune cells in cancer
- Colorectal Cancer Screening and Detection
- MicroRNA in disease regulation
First Affiliated Hospital of Jiamusi University
2019-2023
Taiwan Semiconductor Manufacturing Company (China)
2021
Jiaxing University
2021
Jiamusi University
2020
Nanjing University
2020
Nanjing General Hospital of Nanjing Military Command
2020
Wenzhou Medical University
2017
First Affiliated Hospital of Wenzhou Medical University
2017
Weihai Chest Hospital
2017
Qiqihar Medical University
2010
Abstract Background Inflammation-related predisposition to cancer plays an essential role in progression and is associated with poor prognosis. A hypoxic microenvironment neutrophil infiltration are commonly present solid tumours, including gastric (GC). Neutrophil extracellular traps (NETs) have also been demonstrated the tumour immune (TIME), but how NETs affect GC remains unknown. Here, we investigated of NET formation TIME further explored underlying mechanism growth. Methods...
This study aimed to investigate the correlation between expression of CD24 and B7-H3 in breast cancer tissues clinical significance. Expression adjacent were detected by immunohistochemistry. Quantitative PCR was used detect mRNA tissues. The protein immunoblotting. levels two proteins analyzed relationship 5-year survival patients investigated. positively expressed tissues, CD24-positive rate 75.7 25.7%, respectively, B7-H3-positive 56.8 43.2%, differences statistically significant...
Non-coding RNAs such as long non-coding (lncRNAs) and microRNAs (miRNAs) have been found to be indispensable factors in carcinogenesis cancer development. Numerous studies explored the regulatory functions of these molecules identified synergistic interactions among lncRNAs or miRNAs, while those between miRNAs remain investigated. In this study, we constructed characterized an lncRNA-miRNA network following a four-step approach by integrating pairs expression profiles. The with more shared...
BACKGROUND:Colorectal cancer (CRC) is the second most commonly diagnosed in females and third males worldwide. Although existing evidence explained some critical functions of single genetic abnormality pathogenesis CRC, function interactors involved colon-specific regulatory network, especially DNA methylation regulated network still poorly understood. MATERIAL AND METHODS:In this work, matched gene expression samples CRC patients were retrieved. Differential analyses performed. In addition,...
Objectives: This study was conducted to evaluate the bioequivalence (BE) of a generic form obeticholic acid (OCA) and Ocaliva TM under fasting fed conditions determine effects food on pharmacokinetic (PK) profiles OCA in healthy Chinese subjects. Methods: A randomized, single-dose, three-sequence, three-period, partial replicated crossover with 21-day washout interval between periods (n=48) conditions. Blood samples for its metabolites Glyco-OCA Tauro-OCA were collected up 168 hours after...
This study will investigate the diagnostic accuracy of Ki67 expression in colorectal cancer (CC).A comprehensive search electronic bibliographic databases (MEDLINE, EMBASE, Cochrane Library, Web Science, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure) be performed from inception to February 29, 2020 with no restrictions language publication status. Two authors examine collected studies, extract essential data, appraise quality separately. If possible, we...
This study will explore the association between Ki-67 expression and clinical pathological characteristics (CPC) of colorectal cancer (CC).We search relevant studies from electronic databases (Cochrane Library, PUBMED, EMBASE, Scopus, Cumulative Index to Nursing Allied Health Literature, China Biology Medicine, National Knowledge Infrastructure) beginning April 1, 2020 without language publication time limitations. We consider all case-controlled (CCSs) or randomized controlled (RCSs)...
Pancreatic cancer (PC) is a highly malignant tumor type with high early metastasis rate and no obvious symptoms. Gemcitabine first‑line chemotherapeutic drug for PC. Since there distinct method to determine the efficacy of chemotherapy gemcitabine in patients PC, purpose present study was whether positivity circulating cells (CTCs) advanced PC associated response explore CTCs may be used as predictor prognosis undergoing chemotherapy. First, immunomagnetic microspheres (magnetic beads; MIL)...
Objective To observe how geniposide as an anti-inflammatory agent through inhibition Toll-like receptor 7/nuclear factor-κB signaling pathways activation, well TNF-α and IL-6 release infectioned by influenza virus. Methods Epithelial cells was exposed to human viruses A/Gui/81/23(H3N2) infection for 2 h before treatment with 24 h. NF-κB responsive element luciferase reportor gene transfected dual cis-reporting systems used assay the transcriptional activity of under stimulated circumstance...
Abstract Backgrounds and Aims: Liver cancer stem cells are closely related to the recurrence metastasis of hepatocellular carcinoma (HCC). However, mechanism underlying reciprocity between liver HCC in tumor microenvironment remains unclear. Exosomes act as natural shuttles deliver bioactive molecules that alter behavior recipient cells, offering a new means cell-cell communication for physiological pathological processes liver. This study aimed clarify whether exosomes derived from could...
Objective To systematically evaluate the effectiveness of preoperative prewarming for maintenance intraopera-tive core body temperature, so as to provide clinical evidence perioperative temperature management. Methods We retrieved PubMed, Web Science, Cochrane Library, EMBACE, CINAHL, CNKI, Wanfang Database, CQVIP and China Biology Medicine disc, comprehensively search randomized controlled trials (RCTs) about temperature. The retrieval time was limited from January 2000 April 2019...