Sarah M. Margerison

ORCID: 0000-0001-6846-4328
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About
Contact & Profiles
Research Areas
  • Pain Mechanisms and Treatments
  • Functional Brain Connectivity Studies
  • Musculoskeletal pain and rehabilitation
  • Stress Responses and Cortisol
  • Pain Management and Placebo Effect
  • Neuroscience and Neural Engineering
  • Botulinum Toxin and Related Neurological Disorders
  • Force Microscopy Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Acupuncture Treatment Research Studies
  • Neural and Behavioral Psychology Studies
  • Integrated Circuits and Semiconductor Failure Analysis
  • Hormonal and reproductive studies
  • Temporomandibular Joint Disorders
  • Heart Rate Variability and Autonomic Control

University of Maryland, Baltimore
2022-2025

University of Maryland, College Park
2024

Abstract Background Biomarkers would greatly assist chronic pain management. The present study aimed to undertake analytical validation of a sensorimotor cortical biomarker signature for consisting two measures: peak alpha frequency (PAF) and corticomotor excitability (CME), using human model prolonged temporomandibular (masseter intramuscular injection nerve growth factor [NGF]). Methods 150 participants received an NGF the right masseter muscle on Days 0 2, inducing lasting up 4 weeks....

10.1101/2024.06.16.24309005 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-06-17

Diffuse noxious inhibitory controls (DNICs), or the pain inhibits phenomenon, refer to reduced pain-like behaviors that are displayed following a conditioning stimulus located far from test and have also been referred as "descending control of nociception" when measured in awake-behaving animals. In this study, we sought determine impact moderate long-term exercise on DCN response if effect differed across age sex. After six-week program consisting 30 min treadmill running 5 days week,...

10.3390/biomedicines12051122 article EN cc-by Biomedicines 2024-05-18

Summary Aberrant cognitive network activity and deficits are established features of chronic pain. However, the nature alterations associated with pain their underlying mechanisms require elucidation. Here, we report that claustrum, a subcortical nucleus implicated in modulation, is activated by acute painful stimulation pain-predictive cues healthy participants. Moreover, discover pathological claustrum lateral aspect right dorsolateral prefrontal cortex (latDLPFC) migraine patients....

10.1101/2023.11.01.564054 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-11-02
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