Objective To evaluate the effect of progesterone supplementation during luteal phase on pregnancy outcome in natural frozen-thawed embyo transfer (FTET) cycles. Methods In this retrospective cohort study, 228 consecutive patients who underwent FTET cycles between January 2009 and September 2012 were included. One hundred forty-five received support (P group) but 83 did not receive any (control group). Results There no differences patients' characteristics two groups. The groups similar with...

Abstract A hydrogel microcapsule with an intermediate thin oil layer is presented to achieve smart release of a broad range cargoes triggered via diverse stimuli. microfluidic technique used produce triple emulsion droplets that separates the innermost aqueous phase from prepolymer phase, which transforms into shell photopolymerization. The within acts as effective diffusion barrier, allowing encapsulation various small porous until stimulus applied destabilize layer. It demonstrated stimuli...

Objective To evaluate whether letrozole incorporated in a gonadotrophin-releasing hormone (GnRH) antagonist multiple dose protocol (MDP) improved controlled ovarian stimulation (COS) and vitro fertilization (IVF) results poor responders who underwent IVF treatment. Methods In this retrospective cohort study, total of 103 consecutive cycles that were performed during either the letrozole/GnRH MDP (letrozole group, n=46) or standard GnRH (control n=57) included responders. COS outcomes...

Objective To investigate the prevalence of subclinical hypothyroidism (SH) diagnosed by thyrotropin-releasing hormone (TRH) stimulating test in infertile women with basal thyroid-stimulating (TSH) levels 2.5 to 5.0 mIU/L. Methods This study was performed 39 ovulatory disorders (group 1) and 27 male infertility only 2, controls) who had serum TSH mIU/L a TRH test. Serum were measured before injection (TSH0) also at 20 minutes (TSH1) 40 (TSH2) following intravenous 400 µg TRH. Exaggerated...

This study was performed to evaluate the effects of fibroblast co-culture on in vitro maturation (IVM) prepubertal mouse preantral follicles. The intact follicles were obtained from ovaries 12-14 day old mice and these cultured individually α-minimal essential medium (α-MEM) supplemented with 5% fetal bovine serum (FBS), 100 mIU/Ml recombinant follicle stimulating hormone (rFSH), 1% insulin-transferrin-selenium, μg/ml penicillin 50 μg/Ml streptomycin as base for 12 days. A total 200...

This study was performed to investigate the effect of peroxisome proliferators activated receptor-γ (PPAR-γ) ligand, pioglitazone, on production regulated upon activation normal T-cell expressed and secreted (RANTES) in vitro fertilization (IVF) outcome infertile patients with endometriosis. Sixty-four stage III or IV endometriosis undergoing IVF were randomly allocated control group. The long protocol GnRH agonist (GnRH-a) used for controlled ovarian stimulation (COS) all patients. Patients...

Abstract Previous studies have revealed that a population of innate memory CD8+ T cells is generated in response to IL-4, first appearing the thymus and bearing high expression levels Eomesodermin (Eomes) but not T-bet. However, antigen specificity functional properties these poorly defined. Here we show IL-4 regulates only frequency function also Eomes reactivity naïve cells. Lack responsiveness attenuates capacity mount robust LCMV infection, with both quantitative qualitative effects on...

We previously demonstrated that Bordetella bronchiseptica (B. bronchiseptica) antigen (Ag) enhances the Mycoplasma hyopneumoniae Ag-specific immune response. The focus of this study was whether acellular bacterin B. could be used as an adjuvant to increase antigen-presenting capability dendritic cells (DCs) by increasing level activation. metabolic activity DCs increased bronchiseptica, similar lipopolysaccharide (LPS). Flow cytometry analysis revealed increases expression major...

This study was performed to investigate the expression of cathepsin B mRNA and protein in eutopic ectopic endometrial tissues patients with endometriosis normal clarify association between endometriosis. A total 40 women histologically confirmed were recruited for group. For controls, 20 undergoing operative treatment uterine myoma, cervical intraepithelial neoplasia (CIN) or benign gynecologic conditions other than recruited. Eutopic both groups tissue group collected during operations. We...

Fenbendazole (FBZ) is a benzimidazole anthelmintic widely used to treat parasitic infections. The anticancer effect of FBZ has been recently highlighted leading its consideration as potential agent. Although previous studies have demonstrated the on cancer cells, there paucity lymphoma cells and normal immune cells. Herein, we investigated effects mouse cell line, EL-4 spleen using vincristine positive control. cellular metabolic activity was decreased by FBZ, but that not decreased....

5-Fluorouracil, doxorubicin, and vincristine are chemotherapy agents used to treat various cancers, such as breast cancer lymphoma for decades, their effects on have been proven. On the other hand, these anti-cancer drugs cause fatal side effects, including immunosuppression. This study investigated whether sonicated Bordetella bronchiseptica bacterin can attenuate immunosuppression of spleen cells induced by which subsets were affected. B. increased metabolic activity treated with 3 drugs....

In article number 2009553, Hyomin Lee, Chang-Hyung Choi, and co-workers present hydrogel microcapsules with an intermediate thin oil layer that enable the smart release of a broad range hydrophilic cargoes triggered via diverse stimuli. The osmotic pressure overall stiffness can be fine-tuned to control onset time behavior multi-cargo encapsulated either simultaneous or selective.

Biosilica is a silica-based substance derived from the cell walls (frustules) of diatoms. Recently, research into biosilica’s biological functions underway, but little has been reported on effects biosilica immune cells. In this study, we investigated effect ionized water (iBW) dendritic cells (DCs), which play crucial roles as antigen (Ag)-presenting Treatment with iBW increased expression response-related markers, closely connected to maturation DCs, and production tumor necrosis...