A5054028439- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Capillary Electrophoresis Applications
- Additive Manufacturing and 3D Printing Technologies
- Microfluidic and Bio-sensing Technologies
- Nanofabrication and Lithography Techniques
- Electrowetting and Microfluidic Technologies
- Advanced Thermodynamics and Statistical Mechanics
- Nonlinear Dynamics and Pattern Formation
- Aquatic and Environmental Studies
- Neuroscience and Neural Engineering
- Analytical Methods in Pharmaceuticals
- Pluripotent Stem Cells Research
- Genetics, Bioinformatics, and Biomedical Research
- Advanced Fiber Optic Sensors
- Gene Regulatory Network Analysis
- Electrophoretic Deposition in Materials Science
- Biosensors and Analytical Detection
- Poisoning and overdose treatments
- Analytical Chemistry and Chromatography
- Elasticity and Wave Propagation
- Bone Tissue Engineering Materials
- Mathematical Biology Tumor Growth
- Heat Transfer and Optimization
Dublin City University
2023
ARC Centre of Excellence for Electromaterials Science
2016-2020
University of Tasmania
2016-2020
KLA (Ireland)
2020
University of Glasgow
1977-2018
Australian Centre for Research on Separation Science
2018
University of Amsterdam
2018
Vrije Universiteit Amsterdam
2018
Institute for Molecular Science
2018
Hobart Private Hospital
2016
Three-dimensional (3D) printing has emerged as a potential revolutionary technology for the fabrication of microfluidic devices. A direct experimental comparison three 3D technologies dominating microfluidics was conducted using Y-junction device, design which optimized each printer: fused deposition molding (FDM), Polyjet, and digital light processing stereolithography (DLP-SLA). Printer performance evaluated in terms feature size, accuracy, suitability mass manufacturing; laminar flow...
3D printing enables the rapid and cost-efficient manufacturing of bespoke, complex prototypes. We show that biocompatibility needs to be considered carefully provide a specific assay effect.
One of the largest impediments in development microfluidic-based smart sensing systems is manufacturability integrated, complex devices. Here we propose multimaterial 3D printing for fabrication such devices a single step. A microfluidic device containing an integrated porous membrane and embedded liquid reagents was made by applied analysis nitrate soil. The manufacture sealed realized as print within 30 min. body printed transparent acrylonitrile butadiene styrene (ABS) contained 400 μm...
Multimaterial 3D printing provides a unique capability for the creation of highly complex integrated devices where complementary functionality is realized using differences in material properties. Using single and automated print process, microfluidic were fabricated containing (i) an optically transparent structure fluorescence detection, (ii) electrodes electrokinetic transport, (iii) primary membrane to remove particulates macromolecules including proteins, (iv) secondary concentrate...
Fluidic behavior in microfluidic devices is dictated by low Reynolds numbers, complicating mixing. Here, the effect of orientation extruded filament on fluidic investigated fused deposition modeling (FDM) printed devices. Devices were with orientations at 0°, 30°, 60°, and 90° to direction flow. The extent mixing was observed when pumping yellow blue solutions into inlets a Y-shaped device, measuring two colored under different angles flow rates 25, 50, 100 μL/min. 60° showed highest...
Implementations of Lab-on-a-Chip technologies for in-situ analysis small model organisms and embryos (both invertebrate vertebrate) are attracting an increasing interest. A significant hurdle to widespread applications microfluidic millifluidic devices is the access expensive clean room facilities complex microfabrication technologies. Furthermore, these resources require investments engineering know-how. For example, poly(dimethylsiloxane) soft lithography still largely unattainable gross...
Through optimization of the printing process and orientation, a suitably developed surface area has been realized upon 3D printed polymer substrate to facilitate chromatographic separations in planar configuration. Using an Objet Eden 260VS printer, thin layer chromatography platforms were directly fabricated without any additional functionalization successfully applied separation various dye protein mixtures. The print material was characterized using gas coupled mass spectrometry...
Synthetic micro-diamond-polydimethylsiloxane (PDMS) composite microfluidic chips and thin films were produced using indirect 3D printing spin coating fabrication techniques. Microfluidic containing up to 60 wt% micro-diamond successfully cast bonded. Physicochemical properties, including the dispersion pattern, hydrophobicity, chemical structure, elasticity thermal characteristics of both chip investigated. Scanning electron microscopy indicated that particles embedded interconnected within...
By virtue of its ruggedness, portability, rapid processing times, and ease-of-use, academic commercial interest in centrifugal microfluidic systems has soared over the last decade. A key advantage LoaD platform is ability to automate laboratory unit operations (LUOs) (mixing, metering, washing etc.) support direct translation 'on-bench' assays 'on-chip'. Additionally, requires just a low-cost spindle motor rather than specialized expensive pumps. Furthermore, when flow control (valves)...
A novel fibre-based microfluidic methodology was developed to move and isolate charged solutes, biomolecules, intact bacterial cells, based upon a multi-functional 3D printed platform.
This work describes a preliminary investigation of commercially available 3D printing technologies for rapid prototyping and low volume fabrication Lab-on-a-Chip devices. The main motivation the was to use off-the-shelf methods in order rapidly inexpensively build microfluidic devices with complex geometric features reduce need clear room environment conventional microfabrication techniques. Both multi-jet modelling (MJM) stereolithography (SLA) processes were explored. MJM printed...
Current microfabrication methods are often restricted to two-dimensional (2D) or two and a half dimensional (2.5D) structures. Those fabrication issues can be potentially addressed by emerging additive manufacturing technologies. Despite rapid growth of technologies in tissue engineering, microfluidics has seen relatively little developments with regards adopting 3D printing for complex chip-based devices. This been due major factors: lack sufficient resolution current rapid-prototyping...
3D printed micrometer-scale polymer mounts for single crystal analysis have been prepared by photopolymerization using digital light projection stereolithography (DLP-SLA), with a commercially available printer (US$4000) and 3DM-ABS resin (US$150 per liter). The were in batches of 49 1 h 15 min, which allowed rapid prototyping testing new mounting designs, cost 0.2¢ US mount. suitability the crystallography has demonstrated through their use Cu Kα X-ray diffraction experiments Rochelle salt...
We report upon a novel coplanar dielectrophoresis (DEP) based cell patterning system for generating transferrable hepatic constructs, resembling liver-lobule, in culture. The use of paper reinforced gel substrates provided sufficient strength to enable these constructs be transfered into 96-well plates long term functional studies, including the future, drug development studies. Experimental results showed that cells formed DEP field-induced structures corresponding an array lobule-mimetic...