A5000642907- Heart Failure Treatment and Management
- Blood properties and coagulation
- Potassium and Related Disorders
- Platelet Disorders and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular and exercise physiology
- Cardiovascular Function and Risk Factors
- Inflammatory Biomarkers in Disease Prognosis
- Congenital Heart Disease Studies
- Clinical Laboratory Practices and Quality Control
- Venous Thromboembolism Diagnosis and Management
- Emergency and Acute Care Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Diverse Scientific Research Studies
- Genetics, Bioinformatics, and Biomedical Research
- Psoriasis: Treatment and Pathogenesis
- Cardiovascular and Diving-Related Complications
- Vascular Tumors and Angiosarcomas
- Drug-Induced Ocular Toxicity
- Liver Diseases and Immunity
- Cardiac, Anesthesia and Surgical Outcomes
- Dermatology and Skin Diseases
- Biomarkers in Disease Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Organizational Leadership and Management Strategies
Royal London Hospital
2024-2025
Ziauddin University
2018-2024
Ziauddin Hospital
2018-2024
Fox Chase Cancer Center
2019-2021
University of Nottingham
2021
Temple University
2021
Iqra University
2019
Royal United Hospital
2018
Homerton University Hospital NHS Foundation Trust
2017-2018
Foundation University Medical College
2017
While thrombocytopenia's link to mortality is known, the prognostic impact of longitudinal trajectories platelet indices in combination with analysis mediating role remains unexplored. This first study that addresses this significant gap by investigating association between seven trajectory subphenotypes and ICU mortality, considering influence.
Immature platelet fraction (IPF) estimation is a non-invasive and sensitive test that available on recently introduced Sysmex XN-series of automated haematology analysers. It direct cellular indicator thrombopoiesis. The aim this study was to establish reference intervals for IPF, both absolute (A-IPF) percentage (%-IPF) measurements.A total 2366 samples met the inclusion criteria were assayed full blood count XN-10 non-parametric percentile method used calculating intervals.After outliers...
This study aimed to define the sex-divided reference intervals for platelet indices (mean volume (MPV), distribution width (PDW), large cell ratio (P-LCR) and plateletcrit (PCT)) on Sysmex XN-10.A total of 2376 samples were assayed full blood count XN-10 haematology analyzer. After removing outliers, calculated using mean±2SD. The P value 0.05 was adopted denote statistical significance.There a significance (α=0.05) between MPV (p=0.007), P-LCR (p=0.015) PCT (p<0.001), thus separate these...
Introduction The management of non-alcoholic steatohepatitis (NASH) is an unmet clinical need. Misoprostol, a structural analogue naturally occurring prostaglandin E1, has been reported to decrease proinflammatory cytokine production and may have potential role in treating NASH. We aimed evaluate the efficacy safety misoprostol patients with Methods In this phase 2, double-blind, randomised, placebo-controlled trial, NASH were randomly assigned 1:1 ratio receive 200 µg or placebo thrice...
Objective: To ascertain the diagnostic accuracy of serum PCT as an early biomarker neonatal sepsis using blood culture gold standard, so that condition could be diagnosed and managed to prevent reduce morbidity mortality in neonates.Study Design: Cross-sectional study.
Objective: To find factors related with delayed diagnosis of pulmonary tuberculosis in patients presenting to the hospitals Rawalpindi. Methods: A cross sectional observation study was carried out Benazir Bhutto Hospital, District head quarter Fauji Foundation Military Hospital and Holy Family Rawalpindi from February 2016 September 2016. total one hundred ninety were interviewed through convenient sampling by a formulated questionnaire. Results: Mean delay 114.48 days whereas median 53.5...
Background The Immature Platelet Fraction (IPF) is an indicator of thrombopoiesis which a useful parameter in thrombocytopenia. It demonstrates compensatory mechanisms production platelets, but currently not implemented routine clinical practice. aim this study was to establish the reproducibility and stability IPF, for both percentage (%-IPF) absolute (A-IPF) measurements.Material/methods: A total 71 samples, 45 26 analysis, were assayed full blood count using Sysmex XN-10 analyser at room...
This is the first study in which impact of platelet transfusions on seven indices was evaluated transfusion-dependent patients admitted ICU.
Introduction Cerebral air embolism (CAE) is a rare but serious complication of cardiac procedure, often leading to significant neurological deficits. The study presents case CAE after coronary artery bypass graft (CABG) and systematic review highlight the incidence, symptom presentation, outcomes associated with following surgeries interventions. Case Presentation We present 71‐year‐old African‐American male past medical history hypertension, hyperlipidemia, high‐degree AV block pacemaker,...
Background: Insulin resistance, a major pathogenic factor in Gestational Diabetes Mellitus (GDM), has an inverse correlation with adiponectin; therefore, the role of adiponectin pathogenesis GDM been suggested. The study aimed to determine mean levels and frequency hypoadiponectinemia patients GDM. Methods: was carried out at Dr. Ziauddin University Hospital, Karachi from June 2016 December 2017. A total 99 women age group 15-45 years diagnosed on Oral Glucose Tolerance Test (OGTT) 24-28...