A5054650161- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Hip disorders and treatments
- Machine Learning in Healthcare
- Sepsis Diagnosis and Treatment
- Shoulder Injury and Treatment
- Infectious Diseases and Tuberculosis
- Bacterial Identification and Susceptibility Testing
- Dupuytren's Contracture and Treatments
- Clinical Reasoning and Diagnostic Skills
- Nail Diseases and Treatments
- Musculoskeletal synovial abnormalities and treatments
- Orthopedic Surgery and Rehabilitation
- Infective Endocarditis Diagnosis and Management
- Sports injuries and prevention
- Musculoskeletal pain and rehabilitation
- Explainable Artificial Intelligence (XAI)
- Bone fractures and treatments
- Spine and Intervertebral Disc Pathology
- Genital Health and Disease
- Surgical Sutures and Adhesives
- Pelvic and Acetabular Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Spinal Fractures and Fixation Techniques
Aarhus University
2010-2025
Regional Hospital Horsens
2017-2025
Central Denmark Region
2023
Aarhus University Hospital
2010-2023
Lundbeck Foundation
2012-2019
Lundbeck (Denmark)
2015-2018
Regionshospitalet Silkeborg
2012-2017
Universität Greifswald
2012
Universitätsmedizin Greifswald
2003
Abstract Acute critical illness is often preceded by deterioration of routinely measured clinical parameters, e.g., blood pressure and heart rate. Early prediction typically based on manually calculated screening metrics that simply weigh these such as early warning scores (EWS). The predictive performance EWSs yields a tradeoff between sensitivity specificity can lead to negative outcomes for the patient. Previous work electronic health records (EHR) trained artificial intelligence (AI)...
The timeliness of detection a sepsis incidence in progress is crucial factor the outcome for patient. Machine learning models built from data electronic health records can be used as an effective tool improving this timeliness, but so far, potential clinical implementations has been largely limited to studies intensive care units. This study will employ richer set that expand applicability these beyond Furthermore, we circumvent several important limitations have found literature: (1) Model...
Problem framing is critical to developing risk prediction models because all subsequent development work and evaluation takes place within the context of how a problem has been framed explicit documentation choices makes it easier compare metrics between published studies. In this work, we introduce basic concepts framing, including windows, observation window shifts event-triggers for that strongly affects clinician fatigue caused by false positives. Building on this, apply four different...
Validated patient-reported outcome measures for patients with hip-abductor tendon pathology are lacking. Recent studies indicate that the Copenhagen Hip and Groin Outcome Score (HAGOS), in original or revised scoring format, Oxford (OHS) may be relevant use pathology. The objective of this study was to assess validity Danish version HAGOS, OHS psychometrically This involved six subscales standard one-factor two-factor OHS. We included individual responses HAGOS from 210 (17 men; 193 women;...
Very limited information is available regarding patient-reported health-related quality of life (HRQoL) and hip function following treatment for chronic periprosthetic joint infection (PJI). Patient-reported outcome measures provide essential to clinicians the impact a have on patient's lives. The purpose this study was examine patient reported HRQoL after completed re-implantation in 2-stage revision.82 patients were identified retrospectively National Patient Register. 57 alive asked...
Limited information is available regarding the treatment strategy and prognosis of non-selected patients treated for chronic periprosthetic hip joint infection. Such important as no head-to-head studies on strategies are available. The purpose this study to report a non-selected, consecutive patient population.We identified 130 in National Patient Registry, consecutively infection between 2003-2008 at 11 departments orthopaedic surgery. We extracted demographics, outcome. 82 were...
Aims The aim of this study was to analyze the prevalence culture-negative periprosthetic joint infections (PJIs) when adequate methods culture are used, and evaluate outcome in patients who were treated with antibiotics for a PJI compared those whom withheld. Methods A multicentre observational undertaken: 1,553 acute 1,556 chronic PJIs, diagnosed between 2013 2018, retrospectively analyzed. Culture-negative PJIs according Muskuloskeletal Infection Society (MSIS), International Consensus...
This study evaluates the diagnostic value of ultrasound as a first-line exam in carpal tunnel syndrome. In 16 patients with syndrome and 32 matched controls, evaluation median nerve was performed by cross-sectional area at wrist level wrist-forearm ratio. found statistically significant differences between controls both methods, showed high specificity positive predictive values. Optimal cut-off values were identified 14 mm(2) 1.6 implies that is valuable tool test used surgeon for...
Accurate prediction of outcome following hip arthroscopy is challenging and machine learning has the potential to improve our predictive capability. The purpose this study was determine if analysis Danish Hip Arthroscopy Registry (DHAR) can develop a clinically meaningful calculator for predicting probability patient undergoing subsequent revision surgery primary arthroscopy.Machine performed on DHAR. models within 1, 2, and/or 5 years after arthroscopy. Data were split randomly into...
Background and purpose — Percutaneous needle fasciotomy (PNF) is a minimally invasive treatment option for Dupuytren contracture, which has gained momentum worldwide in recent years. However, evidence regarding safety severe complications associated with PNF sparse. Thus, we evaluated of specific method the largest cohort reported literature. Patients methods This single-center, register-based, observational study on treatments between 2007 2015. The was identified by Danish National Patient...
The diagnosis of orthopedic implant-associated infections (OIAIs) caused by the slow-growing anaerobic bacterium
BackgroundPeriprosthetic Joint Infection (PJI) is a devastating complication in hip and knee joint arthroplasty. The "JS BACH" classification system was developed 2021 to stratify the complexity of PJI, more importantly, act as tool guide referrals specialist centers. has not been validated an external cohort. This study aimed do so using large prospective cohort from Australia New Zealand.MethodsWe applied JS-BACH Prosthetic Zealand Observational (PIANO) newly diagnosed PJI collected 2-year...
INTRODUCTION. Tendinopathy and tendon tears of the gluteus medius and/or minimus (GMM) insertion at greater trochanter are increasingly recognised internationally as a cause recalcitrant lateral hip pain (LHP). The purpose this study was to report first Danish results open surgical repair GMM in female patients. METHODS. In retrospective observational study, we included 67 women (68 hips) with mean (95% confidence interval (CI)) age 59 (56-61) years who underwent between September 2018 June...
Abstract Clinical trials have used antibiotic impregnated impacted bone allograft in revisions of infected arthroplasties. By this method high local concentration and good control infection was achieved. Toxicity studies, however, suggest that can impair osteoblast replication. We therefore asked whether impregnating morselized with different quantities tobramycin before impaction would implant fixation. implanted three cylindrical (10 mm × 6 mm) porous‐coated titanium implants into the...
Purpose Administrative discharge registers could be a valuable and easily accessible single-sources for research data on periprosthetic hip joint infection. The aim of this study was to estimate the positive predictive value International Classification Disease 10 th revision (ICD-10) infection diagnosis code in Danish National Patient Register. Methods Patients were identified with an ICD-10 T84.5 (“Infection inflammatory reaction due internal prosthesis”) association hip-joint associated...