A5032326570- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Hip disorders and treatments
- Rheumatoid Arthritis Research and Therapies
- Pelvic and Acetabular Injuries
- Bone health and osteoporosis research
- Venous Thromboembolism Diagnosis and Management
- Knee injuries and reconstruction techniques
- Health Systems, Economic Evaluations, Quality of Life
- Acute Myocardial Infarction Research
- Bone health and treatments
- Opioid Use Disorder Treatment
- Bone and Joint Diseases
- Bone fractures and treatments
- Sarcoma Diagnosis and Treatment
- Sports injuries and prevention
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Healthcare cost, quality, practices
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Lupus Erythematosus Research
Aarhus University Hospital
2016-2025
Aarhus University
2014-2025
Nestlé (Switzerland)
2024
Danish Pain Research Center
2009-2022
Slagelse Hospital
2019
Gigtforeningen
2019
Region Zealand
2019
Hvidovre Hospital
2019
Copenhagen University Hospital
2019
University of Southern Denmark
2017
Abstract: Missing data are ubiquitous in clinical epidemiological research. Individuals with missing may differ from those no terms of the outcome interest and prognosis general. often categorized into following three types: completely at random (MCAR), (MAR), not (MNAR). In research, seldom MCAR. can constitute considerable challenges analyses interpretation results potentially weaken validity conclusions. A number methods have been developed for dealing data. These include complete-case...
To compare mortality risks in patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD) and RA without ILD.Matched cohort study.The study was conducted Denmark, using nationwide, prospectively collected data.Among diagnosed between 2004 2016, 679 RA-ILD were matched for birth year, gender age at diagnosis 11 722 but ILD.Mortality assessed Kaplan-Meier curves, hazard rate ratios (HRRs) death estimated Cox proportional hazards regression models.The number of prevalent...
Background: Revision anterior cruciate ligament (ACL) reconstruction is poorly described because of its rare incidence and mainly small case series presented in the literature. The Danish ACL registry has monitored development revision since 2005. Hypothesis: We hypothesized that younger patients had a higher risk than older subjective clinical outcome was worse after primary reconstruction. Study Design: Cohort study; Level evidence, 2. Methods: All clinics performing reconstructions...
The risk of revision due to infection after primary total hip arthroplasty (THA) has been reported be increasing in Norway. We investigated whether this increase is a common feature the Nordic countries (Denmark, Finland, Norway, and Sweden).The study was based on Arthroplasty Register Association (NARA) dataset. 432,168 THAs from 1995 2009 were included (Denmark: 83,853, Finland 78,106, Norway 88,455, Sweden 181,754). Adjusted survival analyses performed using Cox regression models with as...
Background: We used the Nordic Arthroplasty Register Association database to evaluate whether age, sex, preoperative diagnosis, fixation, and implant design influence risk of revision arthroplasty due periprosthetic fracture within two years from operation a primary total hip replacement. Methods: Included in study were 325,730 cemented femoral stems 111,899 uncemented inserted 1995 2009. Seven frequently (two [Exeter Lubinus SP II] five [Bi-Metric, Corail, CLS Spotorno, ABG I, II])...
ABSTRACT In this international study, we examined the incidence of hip fractures, postfracture treatment, and all‐cause mortality following based on demographics, geography, calendar year. We used patient‐level healthcare data from 19 countries regions to identify patients aged 50 years older hospitalized with a fracture 2005 2018. The age‐ sex‐standardized rates post‐hip treatment (defined as proportion receiving anti‐osteoporosis medication various mechanisms action [bisphosphonates,...
Revision for prosthetic joint infection (PJI) has a major effect on patients' health but it remains unclear if early PJI after primary THA is associated with high mortality.(1) Do patients revision within 1 year of have increased mortality compared who do not undergo any reason THA? (2) an risk aseptic revision? (3) Are there particular bacteria among that are death?This population-based cohort study was based the longitudinally maintained Danish Hip Arthroplasty Register performed in...
Background and purpose The possibility of comparing results pooling the data has been limited for Nordic arthroplasty registries, because different registration systems questionnaires. We have established a common database, in order to compare demographics total hip replacement surgery between countries. In addition, we plan study patient groups which numbers are too small be studied individual countries.Material methods Primary replacements (THRs) from 1995–2006 were selected study....
Background and purpose The number of national arthroplasty registries is increasing. However, the methods registration, classification, analysis often differ. Methods We combined data from 3 Nordic knee registers, comparing demographics, methods, overall results. Primary arthroplasties during period 1997–2007 were included. Each register produced a dataset predefined variables, after which descriptive survival statistics produced. Results incidence increased in all countries, but most...
Background: The choice of graft for anterior cruciate ligament reconstruction (ACLR) remains controversial, and despite numerous studies, there is still an ongoing debate on this topic. 2 most widely used grafts are the hamstring tendon patellar tendon. Hypothesis: In study, we hypothesized that revision rate after primary ACLR greater when using compared with grafts. Study Design: Cohort study; Level evidence, 2. Methods: From nationwide population-based Danish Knee Ligament Reconstruction...
<b>Objective </b>To assess the failure rate of cemented, uncemented, hybrid, and reverse hybrid total hip replacements in patients aged 55 years or older. <b>Design</b> Register study. <b>Setting</b> Nordic Arthroplasty Association database (combined data from Sweden, Norway, Denmark, Finland). <b>Participants</b> 347 899 performed during 1995-2011. <b>Main outcome measures</b> Probability implant survival (Kaplan-Meier analysis) along with revision for any reason as endpoint (Cox multiple...
Background and purpose — The increased use of patient-reported outcomes (PROs) in orthopedics requires data on estimated minimal clinically important improvements (MCIIs) patient-acceptable symptom states (PASSs). We wanted to find cut-points corresponding PRO change score the acceptable postoperative score, by estimating MCII PASS 1 year after total hip arthroplasty (THA) for Hip Dysfunction Osteoarthritis Outcome Score (HOOS) EQ-5D.Patients methods THA patients from 16 different...
Background and purpose — It has been suggested that the risk of prosthetic joint infection (PJI) in patients with total hip arthroplasty (THA) may be underestimated if based only on registry data. We therefore wanted to estimate "true" incidence PJI THA using several data sources. Patients methods searched Danish Hip Arthroplasty Register (DHR) for primary THAs performed between 2005 2011. Using DHR National (NRP), we identified first revisions any reason those were due PJI. PJIs also an...
There has been a limited amount of research on risk factors for revision due to infection following total hip arthroplasty (THA), probably low absolute numbers revisions. We therefore studied patient- and surgery-related after primary THA in population-based setting.Using the Danish Hip Arthroplasty Registry, we identified 80,756 THAs performed Denmark between Jan 1, 1995 Dec 31, 2008. used Cox regression analysis compute crude adjusted relative (RR) infection. Revision was defined as...
It is envisaged that guidelines for statistical analysis and presentation of results will improve the quality value research. The Nordic Arthroplasty Register Association (NARA) has therefore developed arthroplasty register data. are divided into two parts, one with an introduction a discussion background to (, see pages x-y in this issue), more technical on how specific problems can be handled. This second part contains (1) recommendations interpretation methods used calculate survival, (2)...
Background: Data on the risk factors for venous thromboembolism among patients undergoing total hip replacement and receiving pharmacological thromboprophylaxis are limited. The purpose of this study was to examine potential patient-related following in a nationwide follow-up study. Methods: Using medical databases, we identified all who underwent primary received Denmark from 1995 2006. outcome measure hospitalization with within ninety days surgery. We considered age, sex, indication...
Routinely recorded health data have evolved from mere by-products of care delivery or billing into a powerful research tool for studying and improving patient through clinical epidemiologic research. Big in the context means large interlinkable sets within single country networks multinational databases. Several Nordic, European, other collaborations are now well established. Advantages big epidemiology include improved precision estimates, which is especially important reassuring ("null")...
We examined the risk of thrombotic and major bleeding events in patients undergoing total hip knee replacement (THR TKR) treated with thromboprophylaxis, using nationwide population-based databases. identified 83 756 primary procedures performed between 1997 2011. The outcomes were symptomatic venous thromboembolism (VTE), myocardial infarction (MI), stroke, death requiring hospitalisation within 90 days surgery. A 1114 (1.3%) 483 (0.6%) experienced VTE bleeding, respectively. annual varied...
Background and purpose An earlier Nordic Arthroplasty Register Association (NARA) report on 280,201 total hip replacements (THRs) based data from 1995–2006, Sweden, Norway, Denmark, was published in 2009. The present study assessed THR survival according to country, the NARA database with Finnish included. Material methods 438,733 THRs performed during period 1995–2011 Finland were Kaplan-Meier analysis used calculate probabilities 95% confidence interval (CI). Cox multiple regression,...
Background: The dual-mobility acetabular cup (DMC) has an additional bearing consisting of a mobile polyethylene component between the prosthetic head and outer metal shell. This design gained popularity in revision total hip arthroplasty (THA) primary treatment femoral neck fractures with anticipation reduced risk THA instability. Our aim was to evaluate overall these cups on basis data from Nordic Arthroplasty Register Association (NARA) database, our secondary study specific causes...
Importance Despite increased use of antibiotic-loaded bone cement (ALBC) in joint arthroplasty over recent decades, current evidence for prophylactic ALBC to reduce risk periprosthetic infection (PJI) is insufficient. Objective To compare the rate revision attributed PJI following primary total knee (TKA) using vs plain cement. Design, Setting, and Participants This international cohort study used data from 14 national or regional registries Australia, Denmark, Finland, Germany, Italy, New...