Albert Prats‐Uribe
A5007968730- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Health Systems, Economic Evaluations, Quality of Life
- Rheumatoid Arthritis Research and Therapies
- Genetic Associations and Epidemiology
- Total Knee Arthroplasty Outcomes
- COVID-19 epidemiological studies
- COVID-19 diagnosis using AI
- Sports injuries and prevention
- Machine Learning in Healthcare
- Cardiovascular Effects of Exercise
- Orthopaedic implants and arthroplasty
- Vaccine Coverage and Hesitancy
- Peripheral Neuropathies and Disorders
- Health disparities and outcomes
- Statistical Methods in Clinical Trials
- Venous Thromboembolism Diagnosis and Management
- Tracheal and airway disorders
- Healthcare cost, quality, practices
- Antibiotic Use and Resistance
- Shoulder Injury and Treatment
- Orthopedic Surgery and Rehabilitation
- Cardiovascular Disease and Adiposity
Nuffield Orthopaedic Centre
2019-2025
University of Oxford
2018-2024
Oxford BioMedica (United Kingdom)
2022-2024
NIHR Oxford Musculoskeletal Biomedical Research Centre
2024
Metropolitan University
2024
Case Western Reserve University
2023
Office for National Statistics
2020-2022
Parc de Salut
2018-2020
Hospital Del Mar
2018-2020
Hospital del Mar Research Institute
2019-2020
ABSTRACT In this international study, we examined the incidence of hip fractures, postfracture treatment, and all‐cause mortality following based on demographics, geography, calendar year. We used patient‐level healthcare data from 19 countries regions to identify patients aged 50 years older hospitalized with a fracture 2005 2018. The age‐ sex‐standardized rates post‐hip treatment (defined as proportion receiving anti‐osteoporosis medication various mechanisms action [bisphosphonates,...
Hydroxychloroquine, a drug commonly used in the treatment of rheumatoid arthritis, has received much negative publicity for adverse events associated with its authorisation emergency use to treat patients COVID-19 pneumonia. We studied safety hydroxychloroquine, alone and combination azithromycin, determine risk routine care arthritis.
The risk of venous thromboembolism (VTE) in ambulatory COVID-19 is controversial. In addition, the association vaccination with COVID-19-related VTE and relevant clinical genetic factors remain to be elucidated.To quantify between short-term VTE, study potential protective role vaccination, investigate for post-COVID-19 VTE.This population-based cohort patients from UK Biobank included participants SARS-CoV-2 infection that was confirmed by a positive polymerase chain test reaction result...
ABSTRACT Background Hydroxychloroquine has recently received Emergency Use Authorization by the FDA and is currently prescribed in combination with azithromycin for COVID-19 pneumonia. We studied safety of hydroxychloroquine, alone azithromycin. Methods New user cohort studies were conducted including 16 severe adverse events (SAEs). Rheumatoid arthritis patients aged 18+ initiating hydroxychloroquine compared to those sulfasalazine followed up over 30 days. Self-controlled case series...
Abstract Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use patients. Here, we describe characteristics adults COVID-19 compare them influenza We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) patients, summarising between 4811 11,643 unique aggregate characteristics. patients have been majority male in US Spain, predominantly female...
Abstract Background Before the COVID-19 pandemic, Sexually transmitted infections (STIs) were increasing in Europe, and Spain Catalonia not an exception. has been one of regions with highest number confirmed cases Spain. The objective this study was to estimate magnitude decline, due STI during lockdown de-escalation phases. Methods Interrupted time series analysis performed decline reported - chlamydia, gonorrhoea, syphilis, lymphogranuloma venereum- since historical data, from March 13th...
Abstract Objective To investigate the use of repurposed and adjuvant drugs in patients admitted to hospital with covid-19 across three continents. Design Multinational network cohort study. Setting Hospital electronic health records from United States, Spain, China, nationwide claims data South Korea. Participants 303 264 January 2020 December 2020. Main outcome measures Prescriptions or dispensations any drug on 30 days after date admission for covid-19. Results Of included, 290 131 were...
Abstract The natural history of coronavirus disease 2019 (COVID-19) has yet to be fully described. Here, we use patient-level data from the Information System for Research in Primary Care (SIDIAP) summarise COVID-19 outcomes Catalonia, Spain. We included 5,586,521 individuals general population. Of these, 102,002 had an outpatient diagnosis COVID-19, 16,901 were hospitalised with and 5273 died after either being diagnosed or between 1st March 6th May 2020. Older age, male, having...
To answer a national research priority by comparing the risk-benefit and costs associated with reverse total shoulder replacement (RTSR) anatomical (TSR) in patients having elective primary for osteoarthritis. Population based cohort study using data from National Joint Registry Hospital Episode Statistics England. Public hospitals publicly funded procedures at private England, 2012-20. Adults aged 60 years or older who underwent RTSR TSR osteoarthritis intact rotator cuff tendons. Patients...
Abstract Objectives Recent data suggest higher COVID-19 rates and severity in Black, Asian, minority ethnic (BAME) communities. The mechanisms underlying such associations remain unclear. We aimed to study the association between ethnicity risk of infection disentangle any correlation with socioeconomic deprivation or previous comorbidity. Design Prospective cohort. Setting UK Biobank linked Hospital Episode Statistics (HES) tests until 14 April 2020. Participants participants from England,...
Abstract Objective Patients with autoimmune diseases were advised to shield avoid coronavirus disease 2019 (COVID-19), but information on their prognosis is lacking. We characterized 30-day outcomes and mortality after hospitalization COVID-19 among patients prevalent diseases, compared hospital admissions similar seasonal influenza. Methods A multinational network cohort study was conducted using electronic health records data from Columbia University Irving Medical Center [USA, Optum...
OBJECTIVES To characterize the demographics, comorbidities, symptoms, in-hospital treatments, and health outcomes among children adolescents diagnosed or hospitalized with coronavirus disease 2019 (COVID-19) to compare them in secondary analyses patients previous seasonal influenza 2017–2018. METHODS International network cohort using real-world data from European primary care records (France, Germany, Spain), South Korean claims US claims, hospital databases. We included and/or COVID-19 at...
Abstract Background We investigated whether we could use influenza data to develop prediction models for COVID-19 increase the speed at which can reliably be developed and validated early in a pandemic. Estimated Risk (COVER) scores that quantify patient’s risk of hospital admission with pneumonia (COVER-H), hospitalization requiring intensive services or death (COVER-I), fatality (COVER-F) 30-days following diagnosis using historical from patients flu-like symptoms tested this patients....
Abstract Background In this study we phenotyped individuals hospitalised with coronavirus disease 2019 (COVID-19) in depth, summarising entire medical histories, including medications, as captured routinely collected data drawn from databases across three continents. We then compared COVID-19 to those previously influenza. Methods report demographics, recorded conditions and medication use of patients the US (Columbia University Irving Medical Center [CUIMC], Premier Healthcare Database...
This study aims to estimate the prevalence of autism spectrum disorders (ASD) in 2017 and ASD diagnosis incidence between 2009 children living Catalonia region Spain, their temporal geographical variability. We used administrative data for all aged 2–17 years who were insured public Catalan Health System 2017. identified cases diagnosed (ICD‐9 codes 299.0, 299.1, 299.8, 299.9). estimated overall annual 2017, then stratified by sex, age group, healthcare area. Poisson regression models assess...
Concern has been raised in the rheumatology community regarding recent regulatory warnings that HCQ used coronavirus disease 2019 pandemic could cause acute psychiatric events. We aimed to study whether there is risk of incident depression, suicidal ideation or psychosis associated with as for RA.
Currently, there is a missing link in the natural history of COVID-19, from first (usually milder) symptoms to hospitalization and/or death. To fill this gap, we characterized COVID-19 patients at time which they were diagnosed outpatient settings and estimated 30-day hospital admission fatality rates.
Routinely collected real world data (RWD) have great utility in aiding the novel coronavirus disease (COVID-19) pandemic response. Here we present international Observational Health Data Sciences and Informatics (OHDSI) Characterizing Associated Risks Your Baseline Disease In SARS-COV-2 (CHARYBDIS) framework for standardisation analysis of COVID-19 RWD.
ABSTRACT Purpose The generation of representative disease phenotypes is important for ensuring the reliability findings observational studies. aim this manuscript to outline a reproducible framework reliable and traceable phenotype based on real world data use in Data Analysis Real‐World Interrogation Network (DARWIN EU). We illustrate by generating two diseases: pancreatic cancer systemic lupus erythematosus (SLE). Methods phenotyping process involves 14‐steps standard operating procedure...
To estimate the effect of intra-articular corticosteroid injection (IACI) for osteoarthritis on longer-term incidence pain medications. We conducted a cohort study patients registered in UK Clinical Practice Research Datalink (CPRD) GOLD primary care database with an incident diagnosis knee, hip, hand, or shoulder between 2005-2019. Exposure interest was single repeated use IACI (analysed separately). Main outcome measures were five-year uncombined opioids, opioid-nonopioid analgesic...
Introduction Electronic health records can be used to understand the diverse presentation of post-acute and long-term outcomes following COVID-19 infection. In England, UK Health Security Agency, in collaboration with University Oxford, has created Evaluation Outcomes (ECHOES) dataset monitor how an initial SARS-CoV-2 infection episode is associated changes risk that are recorded routinely collected data. Methods The ECHOES a national-level combining surveillance, administrative, healthcare...
ABSTRACT Background To date, characterisation studies of COVID-19 have focussed on hospitalised or intensive care patients. We report for the first time natural history disease from diagnosis, including both outpatient and hospital care. Methods Data was obtained SIDIAP, a primary records database covering >6 million people (>80% population Catalonia), linked to RT-PCR tests, emergency inpatient, mortality registers. All participants >=15 years, diagnosed with in between 15th March...