Asieh Golozar
- COVID-19 Clinical Research Studies
- Prostate Cancer Treatment and Research
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Global Cancer Incidence and Screening
- Esophageal Cancer Research and Treatment
- Radiopharmaceutical Chemistry and Applications
- Statistical Methods in Clinical Trials
- Health Systems, Economic Evaluations, Quality of Life
- Liver Disease Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Healthcare cost, quality, practices
- Economic and Financial Impacts of Cancer
- Nonmelanoma Skin Cancer Studies
- Hedgehog Signaling Pathway Studies
- SARS-CoV-2 and COVID-19 Research
- Colorectal Cancer Screening and Detection
- Lipoproteins and Cardiovascular Health
- Prostate Cancer Diagnosis and Treatment
- COVID-19 diagnosis using AI
- Radiomics and Machine Learning in Medical Imaging
- Ethics in Clinical Research
- Meta-analysis and systematic reviews
- COVID-19 epidemiological studies
Boston University
2024
Northeastern University
2023-2024
Knexus Research (United States)
2024
Johns Hopkins University
2012-2023
Regeneron (United States)
2020-2023
AstraZeneca (United States)
2020
AstraZeneca (Japan)
2019
Bayer (Germany)
2018
Tehran University of Medical Sciences
2011-2017
Shariati Hospital
2011-2017
There is considerable variation in hypertension prevalence and awareness, their correlates, across different geographic locations ethnic groups. We performed this cross-sectional analysis on data from the Golestan Cohort Study (GCS).
Background Among central and peripheral factors contributing to exercise intolerance (EI) in heart failure (HF), the extent which skeletal muscle (SM) energy metabolic abnormalities occur contribute EI increased fatigability HF patients with reduced or preserved ejection fraction (HFrEF HFpEF, respectively) are not known. An energetic plantar flexion test magnetic resonance spectroscopy were used probe mechanistic vivo relationships among SM high-energy phosphate concentrations,...
Background: Recent recommendations favoring nonfasting lipid assessment may affect low-density lipoprotein cholesterol (LDL-C) estimation. The novel method of LDL-C estimation (LDL-C N ) uses a flexible approach to derive patient-specific ratios triglycerides very cholesterol. This adaptability confer an accuracy advantage in patients over the fixed classic Friedewald F ). Methods: We used US cross-sectional sample 1 545 634 (959 153 fasting ≥10–12 hours; 586 481 nonfasting) from second...
Abstract Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use patients. Here, we describe characteristics adults COVID-19 compare them influenza We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) patients, summarising between 4811 11,643 unique aggregate characteristics. patients have been majority male in US Spain, predominantly female...
Abstract Objective To investigate the use of repurposed and adjuvant drugs in patients admitted to hospital with covid-19 across three continents. Design Multinational network cohort study. Setting Hospital electronic health records from United States, Spain, China, nationwide claims data South Korea. Participants 303 264 January 2020 December 2020. Main outcome measures Prescriptions or dispensations any drug on 30 days after date admission for covid-19. Results Of included, 290 131 were...
A) To characterize the incidence of kidney failure associated with intravitreal anti-vascular endothelial growth factor (VEGF) exposure, and B) compare risk in patients treated ranibizumab, aflibercept, or bevacizumab. Retrospective cohort study across 12 databases Observational Health Data Sciences Informatics (OHDSI) network. Subjects aged ≥18 years ≥3 monthly anti-VEGF medications for a blinding disease (diabetic retinopathy, diabetic macular edema, exudative age-related degeneration,...
Refined grains and white rice have been associated with elevated risk of type 2 diabetes mellitus (T2DM). In this study, we sought to quantify the effect intake on incident T2DM in two prospective population-based cohort studies from Iran, where is one main staple. We used follow-up data 9,182 participants Golestan Cohort Study (GCS, 2004–2007, conducted mainly rural areas) 2,173 Tehran Lipid Glucose (TLGS, 2004–2006) who did not other chronic diseases at baseline. Diet was assessed using...
Background Mutations in STK11 (STK11m) and frequently co-occurring KRAS mutations (KRASm/STK11m) are associated with poor survival metastatic NSCLC (mNSCLC) immuno-oncology trials. There limited data regarding the prognostic significance of these a real-world setting. Methods This retrospective cohort study analyzed de-identified electronic medical records from Flatiron Clinico-Genomic database to identify patients mNSCLC who had initiated first-line immunotherapy (IO; alone or combination)...
Abstract Objective Patients with autoimmune diseases were advised to shield avoid coronavirus disease 2019 (COVID-19), but information on their prognosis is lacking. We characterized 30-day outcomes and mortality after hospitalization COVID-19 among patients prevalent diseases, compared hospital admissions similar seasonal influenza. Methods A multinational network cohort study was conducted using electronic health records data from Columbia University Irving Medical Center [USA, Optum...
OBJECTIVES To characterize the demographics, comorbidities, symptoms, in-hospital treatments, and health outcomes among children adolescents diagnosed or hospitalized with coronavirus disease 2019 (COVID-19) to compare them in secondary analyses patients previous seasonal influenza 2017–2018. METHODS International network cohort using real-world data from European primary care records (France, Germany, Spain), South Korean claims US claims, hospital databases. We included and/or COVID-19 at...
The rising epidemic of diabetes imposes a substantial economic burden on the Middle East. Using baseline data from population based cohort study, we aimed to identify correlates mellitus (DM) in mainly rural Iran. Between 2004 and 2007, 50044 adults between 30 87 years old Golestan Province located Northeast Iran were enrolled Cohort Study. Demographic health-related information was collected using questionnaires. Individuals' body sizes at ages 15 assessed by validated pictograms ranging 1...
Abstract Background In this study we phenotyped individuals hospitalised with coronavirus disease 2019 (COVID-19) in depth, summarising entire medical histories, including medications, as captured routinely collected data drawn from databases across three continents. We then compared COVID-19 to those previously influenza. Methods report demographics, recorded conditions and medication use of patients the US (Columbia University Irving Medical Center [CUIMC], Premier Healthcare Database...
Routinely collected real world data (RWD) have great utility in aiding the novel coronavirus disease (COVID-19) pandemic response. Here we present international Observational Health Data Sciences and Informatics (OHDSI) Characterizing Associated Risks Your Baseline Disease In SARS-COV-2 (CHARYBDIS) framework for standardisation analysis of COVID-19 RWD.
Background: The management of colorectal cancer (CRC) is evolving, with advances in screening and treatment. Objective: To leverage population-based data to generate up-to-date UK estimates age sex-specific incidence overall survival for the period 2000-2021. Design: We analysed nationally representative primary care records from Clinical Practice Research Datalink (CPRD) GOLD replicated CPRD Aurum. calculated rates, short- long-term stratified by age, sex, diagnosis year. Results: Overall...
Water-pipe and smokeless tobacco use have been associated with several adverse health outcomes. However, little information is available on the association between water-pipe heart disease (HD). Therefore, we investigated of smoking chewing nass (a mixture tobacco, lime ash) prevalent HD.
ABSTRACT Objectives To characterize the demographics, comorbidities, symptoms, in-hospital treatments, and health outcomes among children/adolescents diagnosed or hospitalized with COVID-19. Secondly, to describe amongst previous seasonal influenza. Design International network cohort. Setting Real-world data from European primary care records (France/Germany/Spain), South Korean claims US hospital databases. Participants Diagnosed and/or COVID-19 at age <18 between January June 2020;...
In China, esophageal cancer is the fourth leading cause of death where essentially all cases are histologically squamous cell carcinoma (ESCC), in contrast to adenocarcinoma West.Globally, ESCC 2.4 times more common among men than women and recently it has been suggested that sex hormones may be associated with risk ESCC.We examined association between genetic variants hormone metabolic genes a population from north central China high-incidence rates.A total 1026 1452 controls were genotyped...
Abstract Background A detailed characterization of patients with COVID-19 living obesity has not yet been undertaken. We aimed to describe and compare the demographics, medical conditions, outcomes (PLWO) those without obesity. Methods conducted a cohort study based on outpatient/inpatient care claims data from January June 2020 Spain, UK, US. used six databases standardized OMOP common model. defined two non-mutually exclusive cohorts diagnosed and/or hospitalized COVID-19; were followed...
Cooking practices and water sources have been associated with an increased risk of cancer, mainly through exposure to carcinogens such as heterocyclic amines, polycyclic aromatic hydrocarbons, nitrates. Using data from the Golestan case–control study, carried out between 2003 2007 in a high-risk region for esophageal squamous cell carcinoma (ESCC), we sought investigate association food preparation drinking ESCC. Information on methods, water, dietary habits was gathered 300 cases 571...
Trustworthy clinical practice guidelines require reliable systematic reviews of the evidence to support recommendations. Since 2016, American Academy Ophthalmology (AAO) has partnered with Cochrane Eyes and Vision US Satellite update their guidelines, Preferred Practice Patterns (PPP).To describe experiences findings related identifying that topics likely be addressed in 2016 2011 AAO PPP on cataract adult eye.Cross-sectional study. Systematic management were searched for an established...