A5062487780- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- Metabolism, Diabetes, and Cancer
- Chronic Disease Management Strategies
- Nutrition and Health in Aging
- COVID-19 diagnosis using AI
- SARS-CoV-2 and COVID-19 Research
- Cancer, Lipids, and Metabolism
- Climate Change and Health Impacts
- Machine Learning in Healthcare
- Health Promotion and Cardiovascular Prevention
- Global Public Health Policies and Epidemiology
- Air Quality and Health Impacts
- COVID-19 epidemiological studies
- Nutritional Studies and Diet
- Kawasaki Disease and Coronary Complications
- COVID-19 Impact on Reproduction
- Healthcare cost, quality, practices
- Maternal Mental Health During Pregnancy and Postpartum
- Pharmacological Receptor Mechanisms and Effects
- Medical Coding and Health Information
- Biosimilars and Bioanalytical Methods
Institut Universitari d'Investigació en Atenció Primària Jordi Gol
2019-2024
Universitat Autònoma de Barcelona
2019-2024
Erasmus MC
2024
Centre International de Recherche sur le Cancer
2022-2023
Idiap Research Institute
2022
Agència de Salut Pública de Catalunya
2019
Universitat Pompeu Fabra
2019
Abstract Background A high body mass index (BMI) has been associated with increased risk of several cancers; however, whether BMI is related to a larger number cancers than currently recognized unclear. Moreover, waist circumference (WC) more strongly specific not well established. We aimed investigate the associations between and 26 accounting for non-linearity residual confounding by smoking status as compare cancer estimates WC. Methods Prospective cohort study population-based electronic...
Abstract Objective To investigate the use of repurposed and adjuvant drugs in patients admitted to hospital with covid-19 across three continents. Design Multinational network cohort study. Setting Hospital electronic health records from United States, Spain, China, nationwide claims data South Korea. Participants 303 264 January 2020 December 2020. Main outcome measures Prescriptions or dispensations any drug on 30 days after date admission for covid-19. Results Of included, 290 131 were...
Abstract The natural history of coronavirus disease 2019 (COVID-19) has yet to be fully described. Here, we use patient-level data from the Information System for Research in Primary Care (SIDIAP) summarise COVID-19 outcomes Catalonia, Spain. We included 5,586,521 individuals general population. Of these, 102,002 had an outpatient diagnosis COVID-19, 16,901 were hospitalised with and 5273 died after either being diagnosed or between 1st March 6th May 2020. Older age, male, having...
Single body mass index (BMI) measurements have been associated with increased risk of 13 cancers. Whether life course adiposity-related exposures are more relevant cancer factors than baseline BMI (ie, at start follow-up for disease outcome) remains unclear. We conducted a cohort study from 2009 until 2018 population-based electronic health records in Catalonia, Spain. included 2,645,885 individuals aged ≥40 years and free 2009. After 9 follow-up, 225,396 participants were diagnosed cancer....
Abstract Objective Patients with autoimmune diseases were advised to shield avoid coronavirus disease 2019 (COVID-19), but information on their prognosis is lacking. We characterized 30-day outcomes and mortality after hospitalization COVID-19 among patients prevalent diseases, compared hospital admissions similar seasonal influenza. Methods A multinational network cohort study was conducted using electronic health records data from Columbia University Irving Medical Center [USA, Optum...
OBJECTIVES To characterize the demographics, comorbidities, symptoms, in-hospital treatments, and health outcomes among children adolescents diagnosed or hospitalized with coronavirus disease 2019 (COVID-19) to compare them in secondary analyses patients previous seasonal influenza 2017–2018. METHODS International network cohort using real-world data from European primary care records (France, Germany, Spain), South Korean claims US claims, hospital databases. We included and/or COVID-19 at...
Background Metabolic syndrome (MS) is the simultaneous occurrence of a cluster predefined cardiovascular risk factors. Although individual MS components are associated with increased cancer, it still unclear whether association between and cancer differs from cancer. The aim this matched case-control study was to estimate 13 types (1) (2) diagnosis 0, 1 or 2 components. Methods Cases included 183,248 patients ≥40 years SIDIAP database incident diagnosed January 2008-December 2017. Each case...
Routinely collected real world data (RWD) have great utility in aiding the novel coronavirus disease (COVID-19) pandemic response. Here we present international Observational Health Data Sciences and Informatics (OHDSI) Characterizing Associated Risks Your Baseline Disease In SARS-COV-2 (CHARYBDIS) framework for standardisation analysis of COVID-19 RWD.
Electronic health records are becoming an increasingly valuable resource for epidemiology but their data quality needs to be quantified. We aimed validate twenty-five types of incident cancer cases in the Information System Research Primary Care (SIDIAP) Catalonia with population-based registries Girona and Tarragona as gold-standard.We calculated sensitivity, positive predictive values (PPV), time-difference between date diagnosis entered into SIDIAP registries. added hospital discharge...
ABSTRACT Objectives To characterize the demographics, comorbidities, symptoms, in-hospital treatments, and health outcomes among children/adolescents diagnosed or hospitalized with COVID-19. Secondly, to describe amongst previous seasonal influenza. Design International network cohort. Setting Real-world data from European primary care records (France/Germany/Spain), South Korean claims US hospital databases. Participants Diagnosed and/or COVID-19 at age <18 between January June 2020;...
Abstract The relationship between cancer and coronavirus disease 2019 (COVID‐19) infection severity remains poorly understood. We conducted a population‐based cohort study 1 March 6 May 2020 describing the associations risk of COVID‐19 diagnosis, hospitalisation COVID‐19‐related death. Data were obtained from Information System for Research in Primary Care (SIDIAP) database, including primary care electronic health records ~80% population Catalonia, Spain. Cancer was defined as any invasive...
Abstract Context A comprehensive understanding of the association between body mass index (BMI) and coronavirus disease 2019 (COVID-19) is still lacking. Objective To investigate associations BMI risk COVID-19 diagnosis, hospitalization with COVID-19, death after a diagnosis or (subsequent death), accounting for potential effect modification by age sex. Design Population-based cohort study. Setting Primary care records covering &gt;80% Catalan population, linked to regionwide testing,...
Abstract Background A detailed characterization of patients with COVID-19 living obesity has not yet been undertaken. We aimed to describe and compare the demographics, medical conditions, outcomes (PLWO) those without obesity. Methods conducted a cohort study based on outpatient/inpatient care claims data from January June 2020 Spain, UK, US. used six databases standardized OMOP common model. defined two non-mutually exclusive cohorts diagnosed and/or hospitalized COVID-19; were followed...
The primary aim of this work was to convert the Information System for Research in Primary Care (SIDIAP) from Catalonia, Spain, Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM). Our second provide a descriptive analysis COVID-19-related outcomes among general population.We mapped patient-level data SIDIAP OMOP CDM and we performed more than 3,400 quality checks assess its readiness research. We established population cohort as 1st March 2020 identified outpatient...
Abstract Background The natural history of Coronavirus Disease 2019 (COVID-19) has yet to be fully described, with most previous reports focusing on hospitalised patients. Using linked patient-level data, we set out describe the associations between age, gender, and comorbidities risk outpatient COVID-19 diagnosis, hospitalisation, and/or related mortality. Methods A population-based cohort study including all individuals registered in Information System for Research Primary Care (SIDIAP)....
Objective We aimed to estimate how longitudinal trends in cardiovascular disease, hypertension and type 2 diabetes mellitus incidence Catalonia, Spain from 2009 2018 may differ by age, sex socioeconomic deprivation. Design Cohort study using prospectively collected data. Setting Electronic health records primary healthcare centres Spain. Participants 3 247 244 adults (≥40 years). Outcome measures calculated the annual (per 1000 persons-year) rate ratios (IRR) between three time periods of...
To characterise patients with and without prevalent hypertension COVID-19 to assess adverse outcomes in both inpatients outpatients.
Abstract Background Metabolic syndrome (MS) has emerged as a significant global health concern. The relationship between MS and the risk of cancer doesn‘t seem clear, whether examining by components or in combination. objective this study is to examine MS, its components, overall cancer, including 13 specific types. Methods We included 3,918,781 individuals aged 40 years older sourced from SIDIAP database 2008 2017. Cox models were employed with their combinations. A subsample was created...
Abstract Background Few datasets have been established that capture the full breadth of COVID-19 patient interactions with a health system. Our first objective was to create dataset linked primary care data testing, hospitalisation, and mortality at level. second provide descriptive analysis outcomes among general population describe characteristics affected individuals. Methods We mapped patient-level from Catalonia, Spain, Observational Medical Outcomes Partnership (OMOP) Common Data Model...
Abstract Background We investigated the association between body mass index (BMI) and obesity‐related cancer risk among individuals with/without incident hypertension (HTN), type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD) joint associations of overweight/obesity (BMI ≥25 kg/m ) each cardiometabolic condition with Methods conducted a population‐based cohort ( n = 1,774,904 aged ≥40 years free conditions at baseline) study 2010 2018 electronic health records from Spain. Our main...
ABSTRACT Early identification of symptoms and comorbidities most predictive COVID-19 is critical to identify infection, guide policies effectively contain the pandemic, improve health systems’ response. Here, we characterised socio-demographics comorbidity in 3,316,107persons tested 219,072 persons positive for SARS-CoV-2 since January 2020, their key outcomes month following first test. Routine care data from primary electronic records (EHR) Spain, hospital EHR United States (US), claims...