Heba Alghoul

ORCID: 0000-0001-8234-5843
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • COVID-19 and healthcare impacts
  • Viral Infections and Outbreaks Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • COVID-19 diagnosis using AI
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 epidemiological studies
  • COVID-19 and Mental Health
  • Disaster Response and Management
  • Peripheral Neuropathies and Disorders
  • Rheumatoid Arthritis Research and Therapies
  • COVID-19 Impact on Reproduction
  • Drug-Induced Ocular Toxicity
  • Kawasaki Disease and Coronary Complications
  • Advances in Oncology and Radiotherapy
  • Machine Learning in Healthcare
  • Global Health and Surgery
  • Diversity and Career in Medicine
  • Global Security and Public Health
  • Inflammasome and immune disorders
  • Maternal Mental Health During Pregnancy and Postpartum
  • Global Cancer Incidence and Screening
  • Tuberculosis Research and Epidemiology
  • Optical Imaging and Spectroscopy Techniques

Texas Tech University Health Sciences Center
2022-2024

Texas Tech University
2022-2024

University of Dundee
2023

Uppsala University
2023

Lubbock Christian University
2023

Creative Commons
2023

Islamic University of Gaza
2020-2022

Harvard University
2020

University of Oxford
2020

Bond University
2020

Hydroxychloroquine, a drug commonly used in the treatment of rheumatoid arthritis, has received much negative publicity for adverse events associated with its authorisation emergency use to treat patients COVID-19 pneumonia. We studied safety hydroxychloroquine, alone and combination azithromycin, determine risk routine care arthritis.

10.1016/s2665-9913(20)30276-9 article EN cc-by The Lancet Rheumatology 2020-08-21

ABSTRACT Background Hydroxychloroquine has recently received Emergency Use Authorization by the FDA and is currently prescribed in combination with azithromycin for COVID-19 pneumonia. We studied safety of hydroxychloroquine, alone azithromycin. Methods New user cohort studies were conducted including 16 severe adverse events (SAEs). Rheumatoid arthritis patients aged 18+ initiating hydroxychloroquine compared to those sulfasalazine followed up over 30 days. Self-controlled case series...

10.1101/2020.04.08.20054551 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2020-04-10

Abstract Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use patients. Here, we describe characteristics adults COVID-19 compare them influenza We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) patients, summarising between 4811 11,643 unique aggregate characteristics. patients have been majority male in US Spain, predominantly female...

10.1038/s41467-020-18849-z article EN cc-by Nature Communications 2020-10-06

Abstract Objective To investigate the use of repurposed and adjuvant drugs in patients admitted to hospital with covid-19 across three continents. Design Multinational network cohort study. Setting Hospital electronic health records from United States, Spain, China, nationwide claims data South Korea. Participants 303 264 January 2020 December 2020. Main outcome measures Prescriptions or dispensations any drug on 30 days after date admission for covid-19. Results Of included, 290 131 were...

10.1136/bmj.n1038 article EN cc-by BMJ 2021-05-11

Abstract Objective Patients with autoimmune diseases were advised to shield avoid coronavirus disease 2019 (COVID-19), but information on their prognosis is lacking. We characterized 30-day outcomes and mortality after hospitalization COVID-19 among patients prevalent diseases, compared hospital admissions similar seasonal influenza. Methods A multinational network cohort study was conducted using electronic health records data from Columbia University Irving Medical Center [USA, Optum...

10.1093/rheumatology/keab250 article EN cc-by Lara D. Veeken 2021-03-11

OBJECTIVES To characterize the demographics, comorbidities, symptoms, in-hospital treatments, and health outcomes among children adolescents diagnosed or hospitalized with coronavirus disease 2019 (COVID-19) to compare them in secondary analyses patients previous seasonal influenza 2017–2018. METHODS International network cohort using real-world data from European primary care records (France, Germany, Spain), South Korean claims US claims, hospital databases. We included and/or COVID-19 at...

10.1542/peds.2020-042929 article EN cc-by PEDIATRICS 2021-05-28

Abstract Background In this study we phenotyped individuals hospitalised with coronavirus disease 2019 (COVID-19) in depth, summarising entire medical histories, including medications, as captured routinely collected data drawn from databases across three continents. We then compared COVID-19 to those previously influenza. Methods report demographics, recorded conditions and medication use of patients the US (Columbia University Irving Medical Center [CUIMC], Premier Healthcare Database...

10.1101/2020.04.22.20074336 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2020-04-25

Routinely collected real world data (RWD) have great utility in aiding the novel coronavirus disease (COVID-19) pandemic response. Here we present international Observational Health Data Sciences and Informatics (OHDSI) Characterizing Associated Risks Your Baseline Disease In SARS-COV-2 (CHARYBDIS) framework for standardisation analysis of COVID-19 RWD.

10.2147/clep.s323292 article EN cc-by-nc Clinical Epidemiology 2022-03-01

ABSTRACT Objectives To characterize the demographics, comorbidities, symptoms, in-hospital treatments, and health outcomes among children/adolescents diagnosed or hospitalized with COVID-19. Secondly, to describe amongst previous seasonal influenza. Design International network cohort. Setting Real-world data from European primary care records (France/Germany/Spain), South Korean claims US hospital databases. Participants Diagnosed and/or COVID-19 at age <18 between January June 2020;...

10.1101/2020.10.29.20222083 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2020-10-30

Abstract Background The COVID-19 pandemic threatens to overwhelm the capacity of a vulnerable healthcare system in occupied Palestinian territory (oPt). We aimed evaluate availability personal protective equipment (PPE) and level preparedness among HCWs oPt. Methods A cross-sectional study was conducted using validated online questionnaire distributed through convenient sampling between March 30, 2020 April 12, 2020. Outcomes were PPE, workers (HCWs) oPt for pandemic, regional hospital...

10.1186/s12913-021-06804-7 article EN cc-by BMC Health Services Research 2021-08-03

Abstract Background A detailed characterization of patients with COVID-19 living obesity has not yet been undertaken. We aimed to describe and compare the demographics, medical conditions, outcomes (PLWO) those without obesity. Methods conducted a cohort study based on outpatient/inpatient care claims data from January June 2020 Spain, UK, US. used six databases standardized OMOP common model. defined two non-mutually exclusive cohorts diagnosed and/or hospitalized COVID-19; were followed...

10.1038/s41366-021-00893-4 article EN cc-by International Journal of Obesity 2021-07-15

ABSTRACT Early identification of symptoms and comorbidities most predictive COVID-19 is critical to identify infection, guide policies effectively contain the pandemic, improve health systems’ response. Here, we characterised socio-demographics comorbidity in 3,316,107persons tested 219,072 persons positive for SARS-CoV-2 since January 2020, their key outcomes month following first test. Routine care data from primary electronic records (EHR) Spain, hospital EHR United States (US), claims...

10.1101/2020.10.25.20218875 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-10-27

To estimate the proportion of patients hospitalized with COVID-19 who undergo dialysis, tracheostomy, and extracorporeal membrane oxygenation (ECMO). A network cohort study. Seven databases from United States containing routinely-collected patient data: HealthVerity, Premier, IQVIA Hospital CDM, Open Claims, Optum EHR, SES, VA-OMOP. Patients a clinical diagnosis or positive test result for COVID-19. Dialysis, ECMO. 842,928 were included (22,887 77,853 533,997 36,717 4,336 OPTUM 156,187...

10.1101/2020.11.25.20229088 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2020-11-27

Abstract Background: We described the demographics, cancer subtypes, comorbidities, and outcomes of patients with a history coronavirus disease 2019 (COVID-19). Second, we compared hospitalized COVID-19 to diagnosed influenza. Methods: conducted cohort study using eight routinely collected health care databases from Spain United States, standardized Observational Medical Outcome Partnership common data model. Three cohorts were included: (i) COVID-19, (ii) (iii) influenza in 2017 2018....

10.1158/1055-9965.epi-21-0266 article EN cc-by-nc-nd Cancer Epidemiology Biomarkers & Prevention 2021-07-16

Objective: Large international comparisons describing the clinical characteristics of patients with COVID-19 are limited. The aim study was to perform a large-scale descriptive characterization asthma.Methods: We included nine databases contributing data from January June 2020 US, South Korea (KR), Spain, UK and Netherlands. defined two cohorts ('diagnosed' 'hospitalized') based on disease codes. followed index date 30 days or death. performed analysis reported frequency outcomes in people...

10.1080/02770903.2021.2025392 article EN cc-by Journal of Asthma 2022-01-11

Background Completion cholecystectomy (CC) is performed for recurrent or persistent biliary symptoms following subtotal (STC) incomplete (IC). Due to its complexity, cases are often referred hepato-pancreato-biliary (HBP) surgeons. There little published literature on indications outcomes of CC. Methods between 2016 and 2021 by the sole HPB surgeon covering a rural referral base >250-mile radius in West Texas were included. Primary variables interest include Results Of eleven patients...

10.1177/00031348221124331 article EN The American Surgeon 2022-08-27

<ns3:p><ns3:bold>Background</ns3:bold>: Characterization studies of COVID-19 patients with chronic obstructive pulmonary disease (COPD) are limited in size and scope. The aim the study is to provide a large-scale characterization COPD.</ns3:p><ns3:p> <ns3:bold>Methods</ns3:bold>: We included thirteen databases contributing data from January-June 2020 North America (US), Europe Asia. defined two cohorts namely ‘diagnosed’ ‘hospitalized’ cohort. followed index date 30 days or death. performed...

10.12688/wellcomeopenres.17403.3 preprint EN cc-by Wellcome Open Research 2023-01-10

Abstract Background: Routinely collected real world data (RWD) have great utility in aiding the novel coronavirus disease (COVID-19) pandemic response [1,2]. Here we present international Observational Health Data Sciences and Informatics (OHDSI) [3] Characterizing Associated Risks, Your Baseline Disease In SARS-COV-2 (CHARYBDIS) framework for standardisation analysis of COVID-19 RWD. Methods: We conducted a descriptive cohort study using federated network partners United States, Europe (the...

10.21203/rs.3.rs-279400/v1 preprint EN cc-by Research Square (Research Square) 2021-03-01

As the SARS-CoV-2 virus (COVID-19) continues to affect people across globe, there is limited understanding of long term implications for infected patients 1–3 . While some these have documented follow-ups on clinical records, or participate in longitudinal surveys, datasets are usually designed by clinicians, and not granular enough understand natural history patient experiences ‘long COVID’. In order get a complete picture, need use generated data track long-term impact COVID-19 recovered...

10.1101/2021.07.13.21260449 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-07-15
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