A5074433475- COVID-19 Clinical Research Studies
- Pharmacovigilance and Adverse Drug Reactions
- Global Cancer Incidence and Screening
- Pneumocystis jirovecii pneumonia detection and treatment
- Prostate Cancer Treatment and Research
- Cancer Genomics and Diagnostics
- Maternal Mental Health During Pregnancy and Postpartum
- Health Services Management and Policy
- Pancreatic and Hepatic Oncology Research
- Metabolomics and Mass Spectrometry Studies
- Nausea and vomiting management
- COVID-19 Impact on Reproduction
- BRCA gene mutations in cancer
- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Mechanical Circulatory Support Devices
- Radiation Dose and Imaging
- Appendicitis Diagnosis and Management
- Drug-Induced Adverse Reactions
- Healthcare Systems and Reforms
- HIV-related health complications and treatments
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Pharmaceutical Economics and Policy
- Prostate Cancer Diagnosis and Treatment
Northeastern University
2024
Knexus Research (United States)
2024
Bayer (United States)
2022
Johns Hopkins University
2006-2021
Regeneron (United States)
2020
Tehran University of Medical Sciences
2006-2008
World Health Organization Regional Office for the Eastern Mediterranean
2006
Purpose: The COVID-19 pandemic profoundly affected healthcare systems and patients. There is a need to comprehend the collateral effects of on non-communicable diseases. We examined impact short-term survival for common solid tumours, including breast, colorectal, head neck, liver, lung, oesophageal, pancreatic, prostate, stomach cancer in UK. Methods: This was population-based cohort study electronic health records from UK primary care Clinical Practice Research Datalink GOLD database. In...
Background: Pancreatic cancer is the seventh leading cause of related mortality worldwide and fifth in United Kingdom (UK), with incidence rates nearly matching mortality. Methods: We conducted a population-based cohort study using Clinical Practice Research Datalink (CPRD) GOLD Aurum databases including patients aged 18+ at least one year prior data, diagnosed between 2000 2021. estimated incidence, period prevalence, survival one, five, ten years, stratified by age, sex, calendar year....
Breast cancer is the most frequently diagnosed in females globally. However, we know relatively little about trends males. This study describes United Kingdom (UK) secular breast from 2000 to 2021 for both sexes. We describe a population-based cohort using UK primary care Clinical Practice Research Datalink (CPRD) GOLD and Aurum databases. There were 5,848,436 eligible 5,539,681 males aged 18+ years, with ≥ one year of prior data availability period. estimated crude incidence rates (IR),...
The administration of analgesics to patients with acute abdominal pain due appendicitis is controversial. A study was undertaken assess the analgesic effect morphine in appendicitis.A randomised double-blind clinical trial conducted Sina hospital, a general teaching from January 2004 March 2005. Patients scheduled for appendectomy were receive 0.1 mg/kg sulfate or saline (0.9%) maximum dose 10 mg over 5 min period. examined by surgeons not involved their care before and after drug intensity...
Underreporting of Adverse Drug Reactions (ADRs) reduces the sensitivity pharmacovigilance systems. We described ADR reporting and its trend from 1999 to 2017 estimated underreporting in Iranian Pharmacovigilance Center.We expressed number per inhabitants admissions their possible trends. Finally, percentages were by three approaches: prospective studies, literature review, stratification country; proportion was corrected.The 15.3 100 000 (95% CI: 15.2, 15.8) 10.0 9.8, 10.2) 2017, increasing...
Incidence, prevalence, and survival are pertinent measures to inform the management provision of prostate cancer care.
To estimate the proportion of patients hospitalized with COVID-19 who undergo dialysis, tracheostomy, and extracorporeal membrane oxygenation (ECMO). A network cohort study. Seven databases from United States containing routinely-collected patient data: HealthVerity, Premier, IQVIA Hospital CDM, Open Claims, Optum EHR, SES, VA-OMOP. Patients a clinical diagnosis or positive test result for COVID-19. Dialysis, ECMO. 842,928 were included (22,887 77,853 533,997 36,717 4,336 OPTUM 156,187...
ABSTRACT OBJECTIVES To describe comorbidities, symptoms at presentation, medication use, and 30-day outcomes after a diagnosis of COVID-19 in pregnant women, comparison to women with influenza. DESIGN Multinational network cohort SETTING A total 6 databases consisting electronic medical records claims data from France, Spain, the United States. PARTICIPANTS Pregnant ≥ 1 year contributing databases, diagnosed and/or tested positive, or hospitalized COVID-19. The influenza was derived...
Abstract Background Temporal pattern discovery (TPD) is a method of signal detection using electronic healthcare databases, serving as an alternative to spontaneous reporting adverse drug events. Here, we aimed replicate and optimise TPD approach previously used assess temporal signals statins with rhabdomyolysis (in The Health Improvement Network (THIN) database) by the OHDSI tools designed for OMOP data sources. Methods We from Truven MarketScan US Commercial Claims Encounters (CCAE)....
ABSTRACT Objective Most patients severely affected by COVID-19 have been elderly and with underlying chronic disease such as diabetes, cardiovascular disease, or respiratory disease. People living HIV (PLHIV) may greater risk of contracting developing severe due to the infection higher prevalence comorbidities. Design This is a cohort study, including PLHIV diagnosed, hospitalized, requiring intensive services for COVID-19. Methods Data sources include routine electronic medical record...