A5004091567- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Testicular diseases and treatments
- Health Systems, Economic Evaluations, Quality of Life
- Cancer, Lipids, and Metabolism
- Delphi Technique in Research
- Clinical practice guidelines implementation
- Hormonal and reproductive studies
- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Bone health and treatments
- Bladder and Urothelial Cancer Treatments
- Chemotherapy-induced cardiotoxicity and mitigation
- Radiopharmaceutical Chemistry and Applications
- Genital Health and Disease
- Urologic and reproductive health conditions
- Pharmacological Effects and Toxicity Studies
- MRI in cancer diagnosis
- Statistical Methods in Clinical Trials
- Venous Thromboembolism Diagnosis and Management
- Renal cell carcinoma treatment
- Management of metastatic bone disease
- Cancer survivorship and care
- Cardiac, Anesthesia and Surgical Outcomes
- Radiomics and Machine Learning in Medical Imaging
University Medical Center Utrecht
2019-2024
European Association of Urology
2020-2024
Utrecht University
2018-2024
University of Turin
2023
Tufts Medical Center
2023
Cancer Genomics Centre
2023
Heidelberg University
2019-2023
University Hospital Heidelberg
2019-2023
Erasmus MC
2017-2022
Leiden University
2013-2014
Harmonisation of outcome reporting and definitions for clinical trials routine patient records can enable health care systems to provide more efficient outcome-driven patient-centred interventions. We report on the work PIONEER Consortium in this context prostate cancer (PCa).To update integrate existing core sets (COS) PCa different stages disease, assess their applicability, develop standardised prioritised outcomes.We followed a four-stage process involving: (1) systematic reviews; (2)...
To investigate the effect of reader experience and zonal location on occurrence false positives (FPs) in PIRADS (V2) 3, 4, 5 lesions multiparametric (MP)-MRI prostate.This retrospective study included 139 patients who had consecutively undergone an MP-MRI prostate combination with a transrectal ultrasound MRI fusion-guided biopsy between 2014 2017. exams were prospectively read by group inexperienced radiologists (cohort 1; 54 patients) experienced radiologist 2; 85 patients). Multivariable...
Background. Testicular cancer survivors treated with chemotherapy are at increased risk for metabolic syndrome (MetS) and cardiovascular disease (CVD). We explored acute effects of by assessing factors, abdominal fat volume, hepatic triglyceride content (HTC) aortic wall stiffness. Material methods. studied 19 testicular patients (age 20–54 years) before, three nine months after the start chemotherapy. Blood serum was analyzed lipids, glucose insulin. Abdominal visceral subcutaneous volume...
Our aim was to analyze grading variation between pathology laboratories and pathologists within individual using nationwide real-life data.We retrieved synoptic (n = 13,397) narrative 29,377) needle biopsy reports from the Dutch Pathology Registry prostate-specific antigen values The Netherlands Cancer Registration for prostate cancer patients diagnosed January 2017 December 2019. We determined laboratory-specific proportions per histologic grade unadjusted odds ratios (ORs) International...
Conservative management is an option for prostate cancer (PCa) patients either with the objective of delaying or even avoiding curative therapy, to wait until palliative treatment needed. PIONEER, funded by European Commission Innovative Medicines Initiative, aims at improving PCa care across Europe through application big data analytics. To describe clinical characteristics and long-term outcomes on conservative using international large network real-world data. From initial cohort >100 000...