A5032436254- Impact of AI and Big Data on Business and Society
- Regional Socio-Economic Development Trends
- COVID-19, Geopolitics, Technology, Migration
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Tuberculosis Research and Epidemiology
- COVID-19 and Mental Health
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 detection and testing
- Machine Learning in Healthcare
- Mycobacterium research and diagnosis
- Health disparities and outcomes
- Data-Driven Disease Surveillance
- COVID-19 Digital Contact Tracing
- Influenza Virus Research Studies
- Infection Control and Ventilation
- COVID-19 Pandemic Impacts
- Health Systems, Economic Evaluations, Quality of Life
- Infectious Diseases and Tuberculosis
- Health, Environment, Cognitive Aging
- Human Mobility and Location-Based Analysis
- Chronic Disease Management Strategies
Nuffield Orthopaedic Centre
2021-2025
University of Oxford
2021-2025
Oxford BioMedica (United Kingdom)
2024
Metropolitan University
2024
Universitat Politècnica de Catalunya
2018-2023
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2020-2023
Vall d'Hebron Hospital Universitari
2021
BackgroundAlthough vaccines have proved effective to prevent severe COVID-19, their effect on preventing long-term symptoms is not yet fully understood. We aimed evaluate the overall of vaccination long COVID and assess comparative effectiveness most used (ChAdOx1 BNT162b2).MethodsWe conducted a staggered cohort study using primary care records from UK (Clinical Practice Research Datalink [CPRD] GOLD AURUM), Catalonia, Spain (Information System for in Primary Care [SIDIAP]), national health...
Short-term forecasts of infectious disease burden can contribute to situational awareness and aid capacity planning. Based on best practice in other fields recent insights epidemiology, one maximise the predictive performance such if multiple models are combined into an ensemble. Here, we report ensembles predicting COVID-19 cases deaths across Europe between 08 March 2021 07 2022.
Objective To study the association between COVID-19 vaccination and risk of post-COVID-19 cardiac thromboembolic complications. Methods We conducted a staggered cohort based on national campaigns using electronic health records from UK, Spain Estonia. Vaccine rollout was grouped into four stages with predefined enrolment periods. Each stage included all individuals eligible for vaccination, no previous SARS-CoV-2 infection or vaccine at start date. Vaccination status used as time-varying...
Introduction The COVID-19 pandemic had collateral effects on many health systems. Cancer screening and diagnostic tests were postponed, resulting in delays diagnosis treatment. This study assessed the impact of screening, diagnostics incidence breast, colorectal, lung, prostate cancer; whether rates returned to pre-pandemic levels by December, 2021. Methods is a cohort electronic records from United Kingdom (UK) primary care Clinical Practice Research Datalink (CPRD) GOLD database. included...
Abstract While wastewater-based epidemiology has proven a useful tool for epidemiological surveillance during the COVID-19 pandemic, few quantitative models comparing virus concentrations in wastewater samples and cumulative incidence have been established. In this work, simple mathematical model relating concentration full contagion waves was developed. The then used short-term forecasting compared to local linear model. Both scenarios were tested using dataset composed of from 32 treatment...
Bronchiolitis, mostly caused by Respiratory Syncytial Virus (RSV), and influenza among other respiratory infections, lead to seasonal saturation at healthcare centers in temperate areas. There is no gold standard characterize the stages of epidemics, nor risk infections growing. We aimed define a set indicators assess level viral based on both incidence their short-term dynamics, considering epidemical thresholds.
The appearance and fast spreading of Covid-19 took the international community by surprise. Collaboration between researchers, public health workers, politicians has been established to deal with epidemic. One important contribution from researchers in epidemiology is analysis trends so that both current state short-term future can be carefully evaluated. Gompertz model shown correctly describe dynamics cumulative confirmed cases, since it characterized a decrease growth rate showing effect...
To investigate the incidence of coronavirus disease 2019 (COVID-19) in a single-center cohort patients with MS and to explore contribution their comorbidities therapies outcome.A cross-sectional mixed-method study was conducted involving an email-based, self-administered questionnaire sent on May 21, 2020, 586 followed at Unit Hospital Clinic, University Barcelona, along telephone interview, review electronic medical records until June 18, 2020. The cumulative confirmed COVID-19 (positive...
Policymakers need clear, fast assessment of the real spread COVID-19 epidemic in each their respective countries. Standard measures situation provided by governments include reported positive cases and total deaths. While deaths indicate immediately that countries like Italy Spain had worst as mid-April, 2020, alone do not provide a complete picture situation. Different diagnose differently present very distinctive case fatality ratios. Similar levels incidence mortality might hide different...
Objective To assess the effectiveness of mandatory use face covering masks (FCMs) in schools during first term 2021–2022 academic year. Design A retrospective population-based study. Setting Schools Catalonia (Spain). Population 599 314 children aged 3–11 years attending preschool (3–5 years, without FCM mandate) and primary education (6–11 with mandate). Study period From 13 September to 22 December 2021 (before Omicron variant). Interventions quasi-experimental comparison between last...
Background: SARS-CoV-2 variations as well immune protection after previous infections and/or vaccination may have altered the incidence of multisystemic inflammatory syndrome in children (MIS-C). We aimed to report an international time-series analysis MIS-C determine if there was a shift regions or countries included into study. Methods: This is multicenter, international, cross-sectional collected from participant and for period July 2020 November 2021. assessed ratio between cases...
Persistent symptoms following the acute phase of COVID-19 present a major burden to both affected and wider community. We conducted cohort study including over 856,840 first cases, 72,422 re-infections more than 3.1 million negative-test controls from primary care electronic health records Spain UK (Sept 2020 Jan 2022 (UK)/March (Spain)). characterised post-acute identified key associated with persistent disease. estimated incidence rates persisting in general population among patients time....
Abstract Accurate short-term predictions of COVID-19 cases with empirical models allow Health Officials to prepare for hospital contingencies in a two–three week window given the delay between case reporting and admission patients hospital. We investigate ability Gompertz-type empiric provide accurate prediction up two three weeks give large preparation surge virus transmission. stability its accuracy using bi-weekly during last trimester 2020 2021. Using data from 2020, we show that...
Question addressed by the study A radiological index capable of quantifying pulmonary tuberculosis (TB) disease progression on standard Chest X-Ray (CXR) could enhance clinical management and inform therapeutic decision-making. Our objectives were: to develop a that quantitatively assesses TB in patients over course treatment follow-up, evaluate its usefulness using CXRs from cohort patients, validate it with an independent patients. Materials/patients methods An was developed identify...
Introduction Electronic health records can be used to understand the diverse presentation of post-acute and long-term outcomes following COVID-19 infection. In England, UK Health Security Agency, in collaboration with University Oxford, has created Evaluation Outcomes (ECHOES) dataset monitor how an initial SARS-CoV-2 infection episode is associated changes risk that are recorded routinely collected data. Methods The ECHOES a national-level combining surveillance, administrative, healthcare...
Abstract Background Understanding the role of children in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission is critical to guide decision-making for schools pandemic. We aimed describe SARS-CoV-2 among and adult staff summer schools. Methods During July 2020, we prospectively recruited attending Barcelona who had infection. Primary infections were identified through (1) a surveillance program 22 1905 participants, involving weekly saliva sampling reverse-transcription...
The COVID-19 pandemic is changing the world in unprecedented and unpredictable ways. Human mobility, being greatest facilitator for spread of virus, at epicenter this change. In order to study mobility under COVID-19, evaluate efficiency restriction policies, facilitate a better response future crisis, we need understand all possible data sources our disposal. Our work studies private sources, gathered from mobile-phones released by large technological companies. These are special interest...
Background: While vaccines have proved effective to prevent severe COVID-19, their impact long-term symptoms is not yet fully understood. Methods: We conducted staggered cohort studies using primary care records from both the UK and Catalonia (Spain) national health claims Estonia. All adults registered for at least 180 days as of 01/2021 (UK), 02/2021 (Estonia) comprised source population. Vaccination status was used a time-varying exposure, by vaccine rollout period. Vaccinated people were...
Ten million cases of tuberculosis (TB) were reported in 2018 with a further 1.5 deaths attributed to the disease. Improved vaccination strategies are urgently required tackle ongoing global TB epidemic. In absence validated correlate protection, highly characterised pre-clinical models assess protective efficacy new strategies. this study, we demonstrate application rhesus macaque ultra-low dose (ULD) aerosol M. challenge model for evaluation by directly comparing immunogenicity and...
The epidemiological situation generated by COVID-19 has highlighted the importance of applying non-pharmacological measures in management epidemic. Mass screening asymptomatic general population been established as a priority strategy carrying out diagnostic tests to detect possible cases, isolate contacts, cut transmission chains and thus limit spread virus.To evaluate economic impact mass screenings an during first second wave epidemic Catalonia, Spain.Cost-Benefit Analysis based on...
(1) Background: In epidemiological terms, it has been possible to calculate the savings in health resources and reduction effects of COVID vaccines. Conducting an economic evaluation, some studies have estimated its cost-effectiveness; vaccination shows highly favorable results, cost-saving cases. (2) Methods: Cost-benefit analysis campaign North Metropolitan Health Region (Catalonia). An model based on observational data before after comparison is used. The information doses used assigned...
We aim to compare the severity of infections between omicron and delta variants in 609,352 SARS-CoV-2 positive cases using local hospitalization, vaccination, data from Catalan Health Care System (which covers around 7. 8 million people). performed a substitution model establish increase transmissibility variant screening primary care practices (PCP) hospital admissions. In addition, we used this PCP two periods when were, respectively, dominant (above 95% cases). After that,...
Background Despite their clear lesser vulnerability to COVID-19, the extent by which children are susceptible getting infected SARS-CoV-2 and capacity transmit infection other people remains inadequately characterized. We aimed evaluate role of school reopening preventive strategies in place at schools terms overall risk for community transmission, comparing transmission rates as detected a COVID-19 surveillance platform Catalonian Schools incidence level. Methods findings Infections Catalan...