Victòria Fumadó
A5030582896- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Kawasaki Disease and Coronary Complications
- SARS-CoV-2 detection and testing
- Child Welfare and Adoption
- Respiratory viral infections research
- Mosquito-borne diseases and control
- COVID-19 Impact on Reproduction
- Malaria Research and Control
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- Trypanosoma species research and implications
- Diabetes and associated disorders
- Attention Deficit Hyperactivity Disorder
- Immunodeficiency and Autoimmune Disorders
- interferon and immune responses
- Viral Infections and Vectors
- Parasites and Host Interactions
- Dermatological and COVID-19 studies
- COVID-19 and Mental Health
- Child and Adolescent Psychosocial and Emotional Development
- Respiratory Support and Mechanisms
- Child Abuse and Trauma
- Global Maternal and Child Health
- Oral Health Pathology and Treatment
Hospital Sant Joan de Déu Barcelona
2014-2025
Universitat de Barcelona
2009-2024
Institut de Recerca Sant Joan de Déu
2020-2024
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2023-2024
Departament de Salut
2023
Instituto de Salud Carlos III
2023
Centro de Investigación Biomédica en Red
2023
Spanish Clinical Research Network
2023
Hospital Universitario 12 De Octubre
2023
Sant Joan de Déu Research Foundation
2020-2022
Multisystem inflammatory syndrome associated with the SARS-CoV-2 pandemic has recently been described in children (MIS-C), partially overlapping Kawasaki disease (KD). We hypothesized that (a) MIS-C and prepandemic KD cytokine profiles may be unique justify clinical differences observed, (b) SARS-CoV-2–specific immune complexes (ICs) explain immunopathology of MIS-C. Seventy-four were included: 14 MIS-C, 9 patients positive for by PCR without (COVID), KD, 37 healthy controls (HCs)....
Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that follows benign COVID-19. We report autosomal recessive deficiencies of OAS1 , OAS2 or RNASEL five unrelated with MIS-C. The cytosolic double-stranded RNA (dsRNA)–sensing generate 2′-5′-linked oligoadenylates (2-5A) activate the single-stranded RNA–degrading ribonuclease L (RNase L). Monocytic cell lines primary myeloid cells OAS1, OAS2, RNase produce excessive amounts cytokines upon dsRNA acute...
We performed a prospective screening for Trypanosoma cruzi infection in 1350 Latin American pregnant women and their offspring Barcelona, Spain. The rate of seroprevalence was 3.4%, 7.3% the newborns were infected. Routine management programs maternity wards may be warranted.
Abstract Some clusters of children with a multisystem inflammatory syndrome (MIS-C) associated severe acute respiratory coronavirus 2 (SARS-CoV-2) infection have been reported. We describe the epidemiological and clinical features MIS-C in Spain. is potentially condition that presents recent SARS-CoV-2 infection.
Objectives To develop and validate a specific protocol for SARS-CoV-2 detection in breast milk matrix to determine the impact of maternal infection on presence, concentration persistence antibodies. Design patients This is prospective, multicentre longitudinal study (April–December 2020) 60 mothers with and/or who have recovered from COVID-19. A control group 13 women before pandemic were also included. Setting Seven health centres different provinces Spain. Main outcome measures Presence...
El 31 de diciembre 2019, la Comisión Municipal Salud y Sanidad Wuhan (provincia Hubei, China) informó sobre existencia 27 casos neumonía etiología desconocida con inicio síntomas el 8 diciembre, incluyendo 7 graves, exposición común a un mercado marisco, pescado animales vivos en ciudad Wuhan. enero 2020, las autoridades chinas identificaron como agente causante del brote nuevo tipo virus familia Coronaviridae, denominado temporalmente «nuevo coronavirus», 2019-nCoV. 30 2020 Organización...
Background Human milk and infant gut microbiota are essential for the immune system maturation protection against infections. There is scarce information on microbiological composition of breast in general, none from developing countries. The objective study was to characterize mothers infants southern Mozambique, where infections breastfeeding prevalent. Methods A community-based undertaken among 121 pairs women infants. Breast infant's faeces were analyzed by bacterial culture molecular...
In May 2004, after launching a screening programme to detect Trypanosoma cruzi infection in the Latin American population, case of congenital 2-year-old boy was discovered Barcelona. Few cases transmission have been described non-endemic areas and little is known about epidemiological clinical features Chagas disease this context. The increase immigrants Europe USA requires greater surveillance appropriate diagnostic techniques for managing T. infections.
Abstract Objective To describe the burden, clinical characteristics and prognostic factors of severe malnutrition in children under age 5 years. Design Retrospective study hospital-based data systematically collected from January 2001 to December 2010. Setting Rural Mozambican district hospital. Subjects All aged <5 years admitted with malnutrition. Results During 10-year long surveillance, 274 813 belonging Manhiça's Demographic Surveillance System were seen at out-patient clinics,...
Most children and adolescents infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain asymptomatic or develop a mild disease 2019 (COVID-19) that usually does not require medical intervention. However, small proportion of pediatric patients clinical condition, multisystem inflammatory in (MIS-C). The involvement epigenetics control immune response viral activity prompted us to carry out an epigenomic study uncover target loci regulated by DNA methylation could...
COVID-19 affects children to a lesser extent than adults but they can still get infected and transmit SARS-CoV-2 their contacts. Field deployable non-invasive sensitive diagnostic techniques are needed evaluate the infectivity dynamics of in pediatric populations guide public health interventions, particularly if this population is not fully vaccinated. We evaluated utility high-throughput Luminex assays quantify saliva IgM, IgA IgG antibodies against five spike (S) nucleocapsid (N) antigens...
Abstract Background Understanding the role of children in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission is critical to guide decision-making for schools pandemic. We aimed describe SARS-CoV-2 among and adult staff summer schools. Methods During July 2020, we prospectively recruited attending Barcelona who had infection. Primary infections were identified through (1) a surveillance program 22 1905 participants, involving weekly saliva sampling reverse-transcription...
We aimed to identify risk factors causing critical disease in hospitalized children with COVID-19 and build a predictive model anticipate the probability of need for care.We conducted multicenter, prospective study SARS-CoV-2 infection 52 Spanish hospitals. The primary outcome was care. used multivariable Bayesian estimate needing care.The enrolled 350 from March 12, 2020, July 1, 2020: 292 (83.4%) 214 (73.7%) were considered have relevant COVID-19, whom 24.2% required Four major clinical...
There is little evidence regarding the management of refractory giardiasis after treatment with nitroimidazoles. This study estimates proportion persistent in 3 hospitals Barcelona, describes associated risk factors and genotype, evaluates efficacy rate quinacrine those giardiasis.A clinical, prospective, observational was conducted patients treated Those were provided quinacrine. Molecular characterization Giardia isolates performed by polymerase chain reaction amplification a fragment tpi...
Fever without source (FWS) in infants is a frequent cause of consultation at the emergency department, and emergence SARS-CoV-2 could affect approach to those infants. The aim this study define clinical characteristics rates bacterial coinfections < 90 days with FWS as first manifestation infection. This cross-sectional under age positive SARS-CoV2 PCR nasopharyngeal swab/aspirate, attended departments 49 Spanish hospitals (EPICO-AEP cohort) from March 1 June 26, 2020. Three hundred...
Background Despite their clear lesser vulnerability to COVID-19, the extent by which children are susceptible getting infected SARS-CoV-2 and capacity transmit infection other people remains inadequately characterized. We aimed evaluate role of school reopening preventive strategies in place at schools terms overall risk for community transmission, comparing transmission rates as detected a COVID-19 surveillance platform Catalonian Schools incidence level. Methods findings Infections Catalan...
The increased incidence of COVID-19 cases and deaths in Spain March 2020 led to the declaration by Spanish government a state emergency imposing strict confinement measures on population. objective this study was characterize nasopharyngeal microbiota children adults its relation SARS-CoV-2 infection severity during pandemic lockdown Spain. This cross-sectional included family households located metropolitan Barcelona, Spain, with one adult previous confirmed episode or more exposed...
Internationally adopted children seem to be more likely show ADHD-like symptoms than non-adopted children. The aims of this study were explore the existence and/or diagnosis in a sample internationally depending on their country origin and describe links that may exist between display these observed narrative-based attachment patterns. A Catalan 58 aged 7–8 (24 from Eastern Europe, 23 China, 11 Ethiopia) was assessed with Behavioral Assessment System for Children identify symptoms, Friends...
ABSTRACT The attachment pattern of a sample 168 internationally adopted children was explored in this study using the semi‐structured Friends and Family Interview . analysed relation to development adaptive skills as an expression children's resilience. secure rates were slightly lower insecure patterns considerably higher than those normative samples from previous studies. Eastern Europe demonstrated more (odds ratio [OR]= 2.46; confidence interval [CI]= 1.23–3.94), their scores on scales...