A5078065410- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Synthesis and Biological Evaluation
- Insect and Pesticide Research
- Parasites and Host Interactions
- Vector-borne infectious diseases
- Insect Pest Control Strategies
- Vector-Borne Animal Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Insect symbiosis and bacterial influences
- Cardiovascular Issues in Pregnancy
- Dermatological diseases and infestations
- Orthoptera Research and Taxonomy
- Toxin Mechanisms and Immunotoxins
- Viral gastroenteritis research and epidemiology
- Antifungal resistance and susceptibility
- Hemophilia Treatment and Research
- Animal health and immunology
- Diptera species taxonomy and behavior
- Leptospirosis research and findings
- Parasitic Infections and Diagnostics
- Fossil Insects in Amber
- Insect Resistance and Genetics
- Helminth infection and control
- Hidradenitis Suppurativa and Treatments
Universitat de Barcelona
2015-2024
Instituto de Salud Carlos III
2020-2024
Centro de Investigación Biomédica en Red
2022-2024
Barcelona Institute for Global Health
2015-2024
Centre for Biomedical Network Research on Rare Diseases
2023
St. Claraspital
2023
University Hospital of Basel
2022
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2020
Centro Nacional de Epidemiología
2020
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2010-2020
ABSTRACT Chagas’ disease is an emerging public health problem in areas where the not endemic. Treatment with benznidazole has shown efficacy acute stage of disease, but its chronic remains controversial, and unwanted side effects are more frequent severe adults than children. This study describes profile a cohort Trypanosoma cruzi -infected patients European country.
We performed a prospective screening for Trypanosoma cruzi infection in 1350 Latin American pregnant women and their offspring Barcelona, Spain. The rate of seroprevalence was 3.4%, 7.3% the newborns were infected. Routine management programs maternity wards may be warranted.
American Trypanosomiasis or Chagas disease (CD) is a neglected that affects Latin people worldwide. Two old antiparasitic drugs, benznidazole and nifurtimox, are currently used for specific CD treatment with limited efficacy in chronic infections frequent side effects. New drugs needed patients as well immunosuppressed patients, whom the risk of reactivation life-threatening. We describe case systemic lupus erythematosus (SLE) required immunosuppression to control autoimmune process. It was...
The extent of cryptic leishmaniasis in blood donors from a Spanish endemic area, (Eivissa Island) was studied using various immunological and parasitological methods. Sera 656 were analysed: 16 (2.4%) positive by ELISA 50 (7.6%) Western blot. Peripheral mononuclear cells (PBMC) buffy coat (BC) samples, analyzed culture nested-PCR. DNA L. infantum amplified 27 (22.1%) 122 PBMC. Parasites isolated 3 (4.5%) 67 BC cultures the strains identified as zymodeme MON-28. No parasites PBMC culture....
A l'occasion de l'analyse écoépidémiologique d'un mésofoyer marocain leishmaniose cutanée à Leishmania tropica, 7 907 Phlébotomes ♀, capturés au piège CDC, ont été disséqués, l'été l'automne 1989. Parmi les espèces du genre Phlebotomus, seul P. sergenti était porteur promastigotes. Quatre-vingt-neuf souches, appartenant complexe L. ainsi isolées. La fréquence l'infestation vectorielle, nulle en juin, est passée 1,3 % août, pour atteindre 9,9 octobre, situant la période risque fin saison...
Visceral leishmaniasis (VL) caused by Leishmania infantum is a zoonotic disease endemic throughout the Mediterranean basin. The existence of asymptomatic human infection entails risk transmission blood transfusion.The prevalence was studied in 1437 donors from Balearic Islands (Majorca, Formentera, and Minorca) using immunologic (Western blot [WB] delayed-type hypersensitivity [DTH]), parasitologic (culture), molecular (nested polymerase chain reaction [PCR]) methods. In addition, efficiency...
SUMMARY The domestic dog is the reservoir host of Leishmania infantum , causative agent zoonotic visceral leishmaniasis endemic in Mediterranean Europe. Targeted control requires predictive risk maps canine (CanL), which are now explored. We databased 2187 published and unpublished surveys CanL southern A total 947 western met inclusion criteria for analysis, including serological identification infection (504, 369 dogs tested 1971–2006). Seroprevalence was 23 2% overall (median 10%)....
ABSTRACT Chagas disease has spread to areas that are nonendemic for the with human migration. Since no single reference standard test is available, serological diagnosis of chronic requires at least two tests. New-generation techniques have significantly improved accuracy by use a large mixture recombinant antigens different detection systems, such as chemiluminescence. The aim present study was assess overall new-generation kit, Architect (cutoff, ≥1 sample relative light units/cutoff value...
Abstract Purpose Screening for dysphagia at the intensive care unit (ICU) soon after extubation can prevent aspiration, pneumonia, lower mortality, and shorten re-feeding interval. This study aimed to modify Gugging Swallowing Screen (GUSS), which was developed acute stroke patients, validate it extubated patients in ICU. Methods In this prospective study, forty-five who had been intubated least 24 h were recruited consecutively earliest extubation. The modified GUSS-ICU performed twice by...
Journal Article Leishmania tropica in Morocco: infection dogs Get access J. Dereure, Dereure 1Laboratoire de Parasitologie, 163 rue Auguste-Broussonnet, Montpellier, France Search for other works by this author on: Oxford Academic PubMed Google Scholar J.-A. Rioux, Rioux M. Gallego, Gallego 2Departamento Parasitologia, Facultad Farmacia, Barcelona, Spain Perières, Perières F. Pratlong, Pratlong Mahjour, Mahjour 3Service Ministère la Santé Publique, Rabat, Morocco H. Saddiki Transactions of...
Here we report a documented case of congenital transmission Trypanosoma cruzi from Bolivian mother with chronic Chagas disease living in Spain. The serology and blood nested polymerase chain reaction (PCR) were positive for the mother, amastigote forms observed histopathological study placenta umbilical cord. Direct examination, culture, PCR neonate. At age 8 days, neonate began treatment 5-7.5 mg/kg/day benznidazol, which was continued 60 days. negative to T. 20 days after start remained 4...
The Mediterranean basin is an endemic region for canine leishmaniosis (CanL), where it represents a major veterinary problem and raises human health concerns. However, the distribution of disease heterogeneous not all countries locations have been equally studied characterized. This work describes situation CanL in Girona province (Catalonia, Spain), which no data has previously reported, presents relevant study to exemplify other areas with similar characteristics across region. Four...
L'analyse écoépidémiologique d'un foyer marocain de leishmaniose cutanée à Leishmania tropica a permis d'observer un important polymorphisme enzymatique. Sept zymodemes, appartenant ce complexe, ont été identifiés sur la base 149 souches, isolées l'Homme, du Chien et vecteur Phlebotomus sergenti. Les parasites se répartissent en trois sous-groupes dont deux composés zymodèmes « petits variants ». Cette diversité paraît rapport avec l'ancienneté l'infestation qui aurait colonisation même par...
Currently the universally accepted standard procedure for characterizing and identifying strains of Leishmania is isoenzyme analysis. However, in Mediterranean area, despite their very wide geographical distribution, most infantum belong to zymodeme MON-1. In order increase our understanding polymorphism L. infantum, we developed PCR assays amplifying 10 microsatellites sequenced products. The discriminative power microsatellite analysis was tested by using a panel 50 collected from patients...
Background/Aims The epidemiology of Chagas disease, until recently confined to areas continental Latin America, has undergone considerable changes in recent decades due migration other parts the world, including Spain. We studied prevalence disease American patients treated at a health center Barcelona and evaluated its clinical phase. make some recommendations for screening disease. Methodology/Principal Findings performed an observational, cross-sectional study by means...
ABSTRACT Human leishmaniases are widespread diseases with different clinical forms caused by about 20 species within the Leishmania genus. identification is relevant for therapeutic management and prognosis, especially cutaneous mucocutaneous forms. Several methods available to identify from culture, but they have not been standardized majority of currently described species, exception multilocus enzyme electrophoresis. Moreover, these techniques expensive, time-consuming, in all...