- Infective Endocarditis Diagnosis and Management
- Respiratory viral infections research
- Bacterial Identification and Susceptibility Testing
- Streptococcal Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Antibiotic Resistance in Bacteria
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Herpesvirus Infections and Treatments
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Antibiotics Pharmacokinetics and Efficacy
- SARS-CoV-2 detection and testing
- Cytomegalovirus and herpesvirus research
- Antifungal resistance and susceptibility
- Enterobacteriaceae and Cronobacter Research
- Antibiotic Use and Resistance
- Parvovirus B19 Infection Studies
- Mycobacterium research and diagnosis
- Long-Term Effects of COVID-19
- Central Venous Catheters and Hemodialysis
- Neonatal and Maternal Infections
- Fungal Infections and Studies
Marqués de Valdecilla University Hospital
2014-2025
Universidad de Los Andes
2025
Central University Hospital of Asturias
2024
Centro de Investigación Biomédica en Red
2022-2024
Hospital Universitario Virgen Macarena
2015-2024
Instituto de Biomedicina de Sevilla
2024
Universidad de Sevilla
2021-2024
Hospital Universitario La Paz
2014-2023
Instituto de Salud Carlos III
2022-2023
Hospital General Universitario Gregorio Marañón
1998-2023
BackgroundTreatment of multidrug-resistant Acinetobacter baumannii (MDRAB) infection presents a challenge because the scarcity available options. Even though combination therapy (CT) is frequently used in clinical practice, data are needed to support its use instead monotherapy (MT).
We report a rapid increase in enterovirus D68 (EV-D68) infections, with 139 cases reported from eight European countries between 31 July and 14 October 2021. This upsurge is line the seasonality of EV-D68 was presumably stimulated by widespread reopening after COVID-19 lockdown. Most were identified September, but more are to be expected coming months. Reinforcement clinical awareness, diagnostic capacities surveillance urgently needed Europe.
ObjectivesWe describe clinical and microbiological features of infections caused by OXA-48-producing Klebsiella pneumoniae (O48KP) in the setting a prolonged, hospital-wide outbreak detected January 2011.
Background: Real-time reverse transcription-quantitative polymerase chain reaction (RT-qPCR) is the reference laboratory method to diagnose SARS-CoV-2 infection then requires equipment and time-consuming. There a crucial demand for rapid techniques such as antigen detection test. Considering different diagnostic accuracy of tests with other respiratory viruses in adults children, test must be evaluated specifically children. Methods: The purpose this study was evaluate performance Panbio...
Extraintestinal pathogenic Escherichia coli (ExPEC) are a frequent cause of bacteremia and sepsis, but the role ExPEC genetic virulence factors (VFs) in sepsis development outcome is ill-defined. Prospective study including 120 adult patients with E. to investigate impact bacterial host on severity mortality. Patients' clinical demographic data were registered. Phylogenetic background isolates was analyzed by SNP pyrosequencing VFs PCR. The presented an epidemic population structure 6...
Human parechoviruses (HPeV) have been recently recognized as important viral agents in paediatric infections. The aims of this study were to investigate the HPeV infection prevalence infants <1 month Spain and, secondly, analyse clinical and epidemiological characteristics infected patients compared with those by enterovirus (EV). Infants neurological or systemic symptoms included a multicentre prospective study. EV detection RT-PCR genotyping performed cerebrospinal fluids (CSF), sera...
The epidemiology and clinical association of enterovirus (EV) parechovirus (HPeV) infections, as well the type‐distribution‐according‐to‐age, were determined during a 4‐year study period in Spain. During 2010–2013, total 21,832 samples screened for EV detection frequency was 6.5% (1,430). Of EV‐negative samples, only 1,873 from 2011 to 2013 available HPeV testing. detected 42 (2%) them. Positive genotyped using PCR sequencing. infections occurred all age groups patients: neonates (17%),...
IntroductionEnterovirus A71 (EV-A71) is an emerging pathogen that causes a wide range of disorders including severe neurological manifestations. In the past 20 years, this virus has been associated with large outbreaks hand, foot and mouth disease complications in Asia-Pacific region, while Europe mainly sporadic cases have reported. spring 2016, however, EV-A71 outbreak was reported Catalonia spread further to other Spanish regions.AimOur objective investigate epidemiology clinical...
Abstract Introduction and Objectives Atrial fibrillation (AF) is a highly prevalent condition, with projections indicating it will increase in the future. Various ablation techniques exist to try eliminate arrhythmia, but problem of recurrences need for reinterventions are not uncommon. We markers predict which patients benefit from these procedures recur despite our efforts. strain have emerged as novel tool assessing function degree atrial fibrosis, could improve patient selection success...
Abstract Introduction and Objectives Cardiac amyloidosis (AL) is a disease characterized by the abnormal accumulation of anomalous proteins in cardiac tissue, while atrial fibrillation (AF) an exceedingly prevalent arrhythmia current population, often related to amount fibrosis. The echocardiogram has emerged as fundamental tool diagnosis follow-up these patients, strain analysis techniques can provide highly useful additional information on function especially early stages disease. We...
Abstract Introduction and Objectives Cardiac amyloidosis (AL) is a disease characterized by the abnormal accumulation of anomalous proteins in cardiac tissue, while hypertrophic cardiomyopathy (HCM) hereditary thickening muscle, associated with tissue fibrosis dysfunction its natural progression. The echocardiogram has emerged as fundamental tool diagnosis follow-up these patients, strain analysis techniques can provide highly useful additional information on function especially early stages...
Focus group discussions (FGDs) differ from other qualitative data collection techniques because they offer unique insights into how collective sense-making occurs in real time social settings. However, systematic tools to analyze interaction FGDs and the richness of it yields remain scarce. In this article, we propose a seven indicator model, adapted previous studies on FGD quality, assess interaction. We apply model ( n = 12) conducted via instant messaging application WhatsApp as part...
Abstract Background Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging problem in the paediatric population worldwide with high mortality rates bloodstream infection (BSI). Objectives To evaluate predictors of 30 day CRE BSI a cohort. Methods A retrospective observational single-centre study (December 2005–August 2018) was conducted. Cases children 0 to 16 years were included. Microbiological identification (MALDI Biotyper) and antimicrobial susceptibility testing (Vitek2®...
During 2014, enterovirus D68 (EV-D68) outbreaks were described globally, causing severe respiratory diseases in children and, some cases, subsequent paralysis. In this study, the type characterization of (EV) detected illnesses and epidemiology clinical association EV-D68 infections Spain over a five-year period described. A total 546 EV-positive samples from hospitalized patients with included. was most frequently (46.6%, 191/410 typed EV). Other EV species (25.1%), B (27.8%) C (0.5%) also...