A5072028730- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Cardiac Imaging and Diagnostics
- Atomic and Subatomic Physics Research
- Medical Imaging Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Advanced NMR Techniques and Applications
- Cardiovascular Function and Risk Factors
- Electron Spin Resonance Studies
- Cardiac Valve Diseases and Treatments
- Cerebrovascular and Carotid Artery Diseases
- NMR spectroscopy and applications
- Photoacoustic and Ultrasonic Imaging
- Ultrasound Imaging and Elastography
- Radiomics and Machine Learning in Medical Imaging
- Acute Ischemic Stroke Management
- Congenital Heart Disease Studies
- Advanced X-ray Imaging Techniques
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Spectroscopy Techniques in Biomedical and Chemical Research
- Seismic Imaging and Inversion Techniques
- Prostate Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Lanthanide and Transition Metal Complexes
Philips (Germany)
2015-2025
Philips (Finland)
2025
Johns Hopkins Medicine
2013-2023
Johns Hopkins University
2013-2023
Philips (Spain)
2023
University Hospital Cologne
2015-2022
University of Cologne
2018-2022
University Hospital of Zurich
2020-2021
Emory University Hospital
2020
Resonance Research (United States)
2020
The aim of this study was to investigate the robustness and reproducibility radiomic features in different magnetic resonance imaging sequences.A phantom scanned on a clinical 3 T system using fluid-attenuated inversion recovery (FLAIR), T1-weighted (T1w), T2-weighted (T2w) sequences with low high matrix size. For retest data, scans were repeated after repositioning phantom. Test datasets segmented semiautomated approach. Intraobserver interobserver comparison performed. Radiomic extracted...
Thirty-two patients with clinically definite multiple sclerosis were evaluated neuropsychological procedures and magnetic resonance imaging (MRI). Neuropsychological evaluation included assessment of language, memory, cognition, visuospatial skills, depression. Significant impairment in any three areas, compatible diagnosis a dementia syndrome, was observed 28% these patients, lesser or no cognitive characterized the remaining patients. Magnetic used to evaluate number distribution lesions...
Background Among central and peripheral factors contributing to exercise intolerance (EI) in heart failure (HF), the extent which skeletal muscle (SM) energy metabolic abnormalities occur contribute EI increased fatigability HF patients with reduced or preserved ejection fraction (HFrEF HFpEF, respectively) are not known. An energetic plantar flexion test magnetic resonance spectroscopy were used probe mechanistic vivo relationships among SM high-energy phosphate concentrations,...
PurposeTo investigate the potential of combining Compressed Sensing (CS) and a newly developed AI-based super resolution reconstruction prototype consisting series convolutional neural networks (CNN) for complete five-minute 2D knee MRI protocol.MethodsIn this prospective study, 20 volunteers were examined using 3T-MRI-scanner (Ingenia Elition X, Philips). Similar to clinical practice, protocol consists fat-saturated 2D-proton-density-sequence in coronal, sagittal transversal orientation as...
BACKGROUND. Physical frailty in older individuals is characterized by subjective symptoms of fatigue and exercise intolerance (EI). Objective abnormalities skeletal muscle (SM) mitochondrial high-energy phosphate (HEP) metabolism contribute to EI inherited myopathies; however, their presence or link the frail adult unknown.
To evaluate a compressed sensing artificial intelligence framework (CSAI) to accelerate MRI acquisition of the ankle.Thirty patients were scanned at 3T. Axial T2-w, coronal T1-w, and coronal/sagittal intermediate-w scans with fat saturation acquired using only (12:44 min, CS), CSAI an acceleration factor 4.6-5.3 (6:45 CSAI2x), 6.9-7.7 (4:46 CSAI3x). Moreover, high-resolution axial T2-w scan was obtained similar duration compared CS. Depiction presence abnormalities graded. Signal-to-noise...
Before implementing radiomics in routine clinical practice, comprehensive knowledge about the repeatability and reproducibility of radiomic features is required. The aim this study was to systematically investigate influence image processing parameters on from magnetic resonance imaging (MRI) terms feature values as well test-retest repeatability.Utilizing a phantom consisting 4 onions, limes, kiwifruits, apples, we acquired dataset featuring 3 most commonly used MRI sequences T scanner,...
Compressed sensing accelerates magnetic resonance imaging (MRI) acquisition by undersampling of the k-space. Yet, excessive impairs image quality when using conventional reconstruction techniques. Deep-learning-based methods might allow for stronger and thus faster MRI scans without loss crucial quality. We compared approaches parallel (SENSE), a combination compressed (COMPRESSED SENSE, CS), CS deep-learning-based (CS AI) on raw k-space data acquired at different factors. 3D T2-weighted...
To evaluate the diagnostic performance of an automated reconstruction algorithm combining MR imaging acquired using compressed SENSE (CS) with deep learning (DL) in order to reconstruct denoised high-quality images from undersampled patients shoulder pain.Prospectively, thirty-eight (14 women, mean age 40.0 ± 15.2 years) pain underwent morphological MRI a pseudo-random, density-weighted k-space scheme acceleration factor 2.5 CS only. An DL-based (CS DL) was used create reconstructions same...
Background Decreasing MRI scan time is a key factor to increase patient comfort and compliance as well the productivity of scanners. Purpose/Hypothesis Compressed sensing (CS) should significantly accelerate 3D scans. This study evaluated clinical application cost effectiveness accelerated T 2 sequences lumbar spine. Study Type Prospective, cross‐sectional, observational. Population Twenty healthy volunteers 10 patients. Field Strength/Sequence A TSE sequence, identical with three different...
Three-dimensional time-resolved phase-contrast cardiovascular magnetic resonance (4D flow CMR) enables the quantification and visualisation of blood flow, but its clinical applicability remains hampered by long scan time. The aim this study was to evaluate use compressed sensing (CS) with on-line reconstruction accelerate acquisition 4D CMR thoracic aorta. aorta acquired in 20 healthy subjects using CS acceleration factors ranging from 4 10. As a reference, conventional parallel imaging...
Abstract Objectives To evaluate and compare the diagnostic performance of CT-like images based on a 3D T1-weighted spoiled gradient-echo sequence (T1 GRE), an ultra-short echo time (UTE), multi-echo (FRACTURE) with conventional CT in patients suspected osseous shoulder pathologies. Materials methods Patients traumatic dislocation ( n = 46, mean age 40 ± 14.5 years, 19 women) were prospectively recruited received 3-T MR imaging including T1 GRE, UTE, FRACTURE sequences. was performed acute...
To evaluate the utility of nerve diffusion tensor imaging (DTI), cross-sectional area, and muscle magnetic resonance (MRI) multiecho Dixon for assessing proximal injury in chronic inflammatory demyelinating polyneuropathy (CIDP).In this prospective observational cohort study, 11 patients with CIDP healthy controls underwent a multiparametric MRI protocol DTI sciatic assessment proton-density fat fraction biceps femoris quadriceps muscles by MRI. Patients were longitudinally evaluated MRI,...
To assess the performance of prospectively accelerated and deep learning (DL) reconstructed T2-weighted (T2w) imaging in volunteers patients with histologically proven prostate cancer (PCa).Prospectively undersampled T2w datasets were acquired acceleration factors 1.7 (reference), 3.4 4.8 10 healthy 23 PCa. Image reconstructions using compressed SENSE (C-SENSE) a combination C-SENSE DL-based artificial intelligence (C-SENSE AI) analyzed. Qualitative image comparison was performed 6-point...
In stroke magnetic resonance imaging (MRI), contrast-enhanced angiography (CE-MRA) is the clinical standard to depict extracranial arteries but native MRA techniques are of increased interest facilitate practice. The purpose this study was assess detection internal carotid artery (ICA) stenosis and plaques as well image quality cervical between a novel flow-independent relaxation-enhanced without contrast triggering (REACT) sequence CE-MRA in acute ischemic (AIS).In retrospective,...
Abstract Purpose T 1 mapping is a widely used quantitative MRI technique, but its tissue‐specific values remain inconsistent across protocols, sites, and vendors. The ISMRM Reproducible Research Quantitative MR study groups jointly launched challenge to assess the reproducibility of well‐established inversion‐recovery using acquisition details from seminal paper on standardized phantom in human brains. Methods protocol Barral et al. (2010). Researchers collected data ISMRM/NIST and/or Data...
Abstract Background We evaluated the acceleration of a three-dimensional isotropic flow-independent magnetic resonance angiography (MRA) (relaxation-enhanced without contrast and triggering, REACT) neck arteries using compressed SENSE (CS) combined with deep learning (adaptive intelligence, AI)-based reconstruction (CS-AI). Methods Thirty-four volunteers received 3-T REACT MRA, acquired threefold: (i) CS factor 7 (CS7), scan time 1:20 min:s; (ii) 10 (CS10), 0:55 (iii) CS-AI (CS10-AI), min:s....
A fast T1 mapping method of the whole pancreas remains a challenge, due to complex anatomy organ. In addition, technique for water is needed, since biased in presence fat. The purpose this work accelerate acquisition selective (wT1) at 3 T. proposed combines continuous inversion-recovery Look-Locker with single-shot gradient echo spiral readout, water-fat separation and dictionary matching wT1 bias fat was evaluated phantom by comparing modified (MOLLI) MRS measurements. present validated 11...
Objective Relaxation-Enhanced Angiography without Contrast and Triggering (REACT) is a novel 3D isotropic flow-independent non-contrast-enhanced MRA (non-CE-MRA) has shown promising results in imaging of the thoracic aorta, primarily patients prior aortic surgery. The purpose this study was to evaluate performance REACT after surgery root and/or ascending aorta by performing an intraindividual comparison CE-MRA. Material methods This retrospective single center included 58 MRI studies 34...