- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Advanced MRI Techniques and Applications
- Medical Imaging Techniques and Applications
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Disease and Adiposity
- Viral Infections and Immunology Research
- Photoacoustic and Ultrasonic Imaging
- Liver Disease Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Atomic and Subatomic Physics Research
- Cerebrovascular and Carotid Artery Diseases
- Aortic aneurysm repair treatments
- Cardiovascular Effects of Exercise
- Liver Disease and Transplantation
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Radiology practices and education
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Diagnosis and Treatment
Johannes Gutenberg University Mainz
2016-2025
Medical University of South Carolina
2020-2025
German Centre for Cardiovascular Research
2020-2025
University Medical Center of the Johannes Gutenberg University Mainz
2014-2025
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
2014-2025
University Hospital Cologne
2025
Ludwig-Maximilians-Universität München
2024
Siemens (Germany)
2024
University Medical Center
2020-2023
Felix Platter-Hospital
2023
Background The coronavirus disease 2019 (COVID-19) pandemic led to far-reaching restrictions of social and professional life, affecting societies all over the world. To contain virus, medical schools had restructure their curriculum by switching online learning. However, only few implemented such novel learning concepts. We aimed evaluate students’ attitudes provide a broad scientific basis guide future development education. Methods Overall, 3286 students from 12 different countries...
Background Coronary CT angiography is a first-line test in coronary artery disease but limited by severe calcifications. Photon-counting-detector (PCD) improves spatial resolution. Purpose To investigate the effect of improved resolution on stenosis assessment and reclassification. Materials Methods stenoses were evaluated prospectively vessel phantom (in vitro) containing two (25%, 50%), retrospectively patients vivo) who underwent ultrahigh-spatial-resolution cardiac PCD (from July 2022 to...
Calcium blooming causes stenosis overestimation on coronary CTA.
The aim of this study was to evaluate coronary computed tomography angiography (CCTA)-based in vitro and vivo artery calcium scoring (CACS) using a novel virtual noniodine reconstruction (PureCalcium) on clinical first-generation photon-counting detector-computed system compared with noncontrast (VNC) reconstructions true (TNC) acquisitions.Although CACS CCTA are well-established techniques for the assessment disease, they complementary acquisitions, translating into increased scan time...
Photon-counting detector computed tomography (PCD-CT) has the potential to significantly improve CT imaging in many ways including, but not limited to, low-dose high-resolution (HRCT) of lung. The aim this study was perform an intrapatient comparison radiation dose and image quality PCD-CT compared with conventional energy-integrating (EID-CT).A total 32 consecutive patients available EID-CT HRCT scans were included final analysis. index (CTDI vol ) extracted from patient reports....
The aim of this study was to evaluate strategies reduce contrast media volumes for coronary computed tomography (CT) angiography on a clinical first-generation dual-source photon-counting detector (PCD)-CT system using dynamic circulation phantom.Coronary CT angiograph is an established method the assessment artery disease that relies administration iodinated media. Reduction while maintaining diagnostic image quality desirable. In study, phantom containing 3-dimensional-printed model...
Background Photon-counting detector (PCD) CT provides comprehensive spectral data with every acquisition, but studies evaluating myocardial extracellular volume (ECV) quantification use of PCD compared an MRI reference remain lacking. Purpose To compare ECV for tissue characterization between a first-generation system and cardiac MRI. Materials Methods In this single-center prospective study, adults without contraindication to iodine-based contrast media underwent same-day native...
The aim of this study was to evaluate the impact virtual monoenergetic imaging (VMI) and quantum iterative reconstruction (QIR) on accuracy coronary artery calcium scoring (CACS) using a noniodine (VNI) algorithm first-generation, clinical, photon counting detector computed tomography system.Coronary evaluated in an anthropomorphic chest phantom simulating 3 different patient sizes by 2 extension rings (small: 300 × 200 mm, medium: 350 250 large: 400 mm) patients (n = 61; final analyses only...
Abstract Background Beam hardening (BH) artifacts negatively influence computed tomography (CT) measurements, especially when due to dense materials or with high effective atomic numbers. Photon-counting detectors (PCD) are more susceptible BH equal weighting of photons regardless their energies. The problem is further confounded by the use contrast agents (CAs) K -edge in diagnostic CT energy range. We quantified effect different comparing energy-integrating detector (EID)-CT and PCD-CT....
Please see the Editorial Comment by Edwin F. Donnelly discussing this article.
BACKGROUND: A recent simulation study proposed that stenosis measurements on coronary computed tomography (CT) angiography are influenced by the improved spatial resolution of photon-counting detector (PCD)-CT. The aim current was to evaluate impact ultrahigh-spatial-resolution (UHR) and Coronary Artery Disease Reporting Data System (CAD-RADS) reclassification rates in patients undergoing CT both PCD-CT energy-integrating (EID)-CT compare against quantitative angiography. METHODS: Patients...
To compare coronary artery calcium volume and score (CACS) between photon-counting detector (PCD) conventional energy integrating (EID) computed tomography (CT) in a phantom prospective patient study. A commercially available CACS was scanned with standard protocol (120 kVp, slice thickness/increment 3/1.5 mm, quantitative Qr36 kernel), filtered back projection on the EID-CT, monoenergetic reconstruction at 70 keV quantum iterative off PCD-CT. The same settings were used to prospectively...
Diagnosing myocarditis relies on multimodal data, including cardiovascular magnetic resonance (CMR), clinical symptoms, and blood values. The correct interpretation integration of CMR findings require radiological expertise knowledge. We aimed to investigate the performance Generative Pre-trained Transformer 4 (GPT-4), a large language model, for report-based medical decision-making in context cardiac MRI suspected myocarditis.