- Cardiac Imaging and Diagnostics
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Inflammatory mediators and NSAID effects
- Infective Endocarditis Diagnosis and Management
- Drug-Induced Adverse Reactions
- Advanced MRI Techniques and Applications
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- Cardiac Health and Mental Health
- MRI in cancer diagnosis
- Cardiac electrophysiology and arrhythmias
- Pharmacovigilance and Adverse Drug Reactions
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Estrogen and related hormone effects
- Cerebrovascular and Carotid Artery Diseases
- Coronary Artery Anomalies
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac tumors and thrombi
- Peptidase Inhibition and Analysis
- Coronary Interventions and Diagnostics
- Aortic Disease and Treatment Approaches
University Hospital Cologne
2024-2025
University of Cologne
2024-2025
University Medical Centre Mannheim
2018-2022
Heidelberg University
2018-2022
University of Mannheim
2021
University Hospital Heidelberg
2019-2020
German Centre for Cardiovascular Research
2019-2020
Health First
2019
Eastbourne District General Hospital
1977
Objective Relaxation-Enhanced Angiography without Contrast and Triggering (REACT) is a novel 3D isotropic flow-independent non-contrast-enhanced MRA (non-CE-MRA) has shown promising results in imaging of the thoracic aorta, primarily patients prior aortic surgery. The purpose this study was to evaluate performance REACT after surgery root and/or ascending aorta by performing an intraindividual comparison CE-MRA. Material methods This retrospective single center included 58 MRI studies 34...
OBJECTIVE--To assess whether, on the basis of one blood test, penicillin allergy might be excluded sufficiently for general practitioners to give oral patients claiming a history allergy. DESIGN--Prospective study referred by practitioners. SETTING--Outpatient clinic in district hospital. PATIENTS--175 who gave immediate type reaction penicillin, whom 144 attended as requested and 132 completed investigations. MAIN OUTCOME MEASURES--History examination, serum radioallergosorbent test...
A novel echocardiography-based definition of atrial functional tricuspid regurgitation (A-FTR) has shown superior outcomes in patients undergoing conservative treatment or valve transcatheter edge-to-edge repair. Its prognostic significance for annuloplasty (TTVA) is unknown. This study sought to investigate prognostic, clinical, and technical implications A-FTR phenotype TTVA. multicenter investigated clinical echocardiographic up 1 year 165 consecutive who underwent TTVA (characterized by...
Abstract Recent studies have reported that takotsubo syndrome (TTS) patients are suffering from life-threatening arrhythmias. The aim of our study was to understand the short and long-term usefulness cardiac implantable electronic devices in TTS patients.We constituted a collective 142 bi-centric diagnosed with between 2003 2017. patient groups, divided according treatment (n = 9, 6.3%) or without 133, 93.7%), were followed-up determine importance its complications. One treated permanent...
Thromboembolic events are a common complication in Takotsubo syndrome (TTS). However, their long-term incidence compared with acute coronary (ACS) is lacking. In-hospital and of thromboembolic 138 consecutive patients TTS were sex- age-matched ACS. Predictors analyzed. The was 2-fold higher than ACS (21% vs 9%; P < .01) over mean follow-up 5 years. Although the left ventricular ejection fraction (LVEF) at event significantly lower (38% [9%] 54% [11%]; .01), LVEF comparable. Patients...
Fibromas are rare primary benign cardiac tumours that can become symptomatic due to expansive growth, ventricular rhythm disturbances, and sudden death. Distinguishing fibromas from other (malign) masses is essential for accurate diagnosis treatment. While there some experience in management of children, adult patients unknown.
The pathophysiology of takotsubo syndrome (TTS) is unclear so far. There strong association the occurrence TTS and malignant diseases. An between diseases myocardial infarction (MI) was found recently ascribed to common molecular lifestyle mechanisms.To compare outcome patients with MI or in a matched cohort.Patients (n = 138 per group) were for age sex assessed retrospectively prospectively. Occurrence clinical followed up over 4 years.At time index event, 8 (5.8%) 17 (12.3%) already...
Takotsubo Syndrome (TTS) is an acute reversible left ventricular dysfunction. Recently published studies have highlighted a similar mortality rate as coronary syndrome (ACS). We compared the impact of gender differences on outcome TTS patients to ACS patient.We included collective 138 between 2003 and 2016 at our institution. Patients were divided according their into two groups (Males n=21, 15% females, n=117, 85%). They with cohort 300 diagnosis ACS.On phase, in male TTS, treatment...
The prognosis for patients diagnosed with Takotsubo syndrome (TTS) has generally been considered to be favourable. Nevertheless, recently published data indicate that TTS is associated ventricular fibrillation, cardiogenic shock, right involvement, and thrombo-embolic events.1 Stroke a similarly debilitating complication, which recognized increasingly relevant in acute coronary (ACS) patients,2 thus prompting us explore compare the relationship of stroke too. In our present analysis, we...
Background Takotsubo syndrome (TTS) and acute coronary (ACS) patients have a similar mortality rate. In this study, we sought to determine the short- long-term outcome of TTS as compared ACS both treated with beta-blockers. Objectives present study described data 5 years follow up 103 422 Methods Data from were included retrospectively prospectively, retrospectively. All been followed for five years. The end point in was occurrence death. Results affected significantly more women (87.4%)...
Recent studies have highlighted that Takotsubo syndrome (TTS), mimicking acute coronary (ACS), is associated with poor clinical outcome. TTS different repolarization disorders including ST-segment elevation. ST elevation myocardial infarction (STEMI) in ACS declined prognosis. However, the and prognostic impact of on remains lacking.The aim this study was to determine short- long-term patients as compared STEMI patients.Our institutional database constituted a consecutive cohort 138 matched...
Background: A considerable amount of evidence has shown that acute cardiovascular diseases exhibit specific temporal patterns in their onset. Aim: This study was performed to determine if takotsubo syndrome (TTS) shows chronobiological variations with short and long-term impacts on adverse events. Design: Our institutional database constituted a collective 114 consecutive TTS patients between 2003 2015. Methods: Patients were divided into groups defined by the onset as per time day, day...
Abstract Background Bleeding is the most common complication after percutaneous leaflet-based tricuspid valve repair and associated with acute kidney injury (AKI) adverse outcome. TTVA Cardioband system a technically more complex procedure; however, frequency prognostic impact of postinterventional bleeding renal complications have not been thoroughly examined. Aims This study was performed to determine incidence clinical (MVARC criteria) (KDIGO following transcatheter annuloplasty (TTVA)....
Abstract Background Previous studies revealed that patients with Takotsubo syndrome (TTS) have a higher mortality rate than the general population and comparable to acute coronary (ACS). Repolarisation abnormalities, namely T‐wave amplitude, may provide incremental prognostic information, in addition traditional risk factors ACS. This study was performed determine short‐ long‐term impact of inverted T‐waves TTS patients, as compared ACS patients. Methods results Our institutional database...
Background/Aim: The association between ejection fraction (EF) and mortality in TTS patients as compared to ACS is limited. This study aims investigate the EF clinical outcomes with ACS. Patients Methods: in-hospital, long-term incidence of for 5 years was composed two groups EF≥35% EF<35%. Results: significantly higher (18.1% vs. 7.7%, log-Rank; p<0.01). Irrespective EF, a non-cardiovascular death EF≥35 (6.4% 2.1%; p=0.02) EF<35% (21.4% 7.5%; p=0.03). Conclusion: dominated by cause...
The pathophysiology of Takotsubo Syndrome (TTS) is not completely understood and the trigger sudden cardiac death (SCD) in TTS clear either. We therefore sought to find an association between primary electrical diseases. A total 148 patients were analyzed 2003 2017 a bi-centric manner. Additionally, literature review was performed. included ongoing retrospective cohort database. coexistence diseases confirmed five cases as following: catecholaminergic polymorphic ventricular tachycardia...