Jordi Casabona
A5090877463- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Sex work and related issues
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- Hepatitis C virus research
- Syphilis Diagnosis and Treatment
- Reproductive tract infections research
- HIV-related health complications and treatments
- Hepatitis B Virus Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS drug development and treatment
- COVID-19 Clinical Research Studies
- Viral-associated cancers and disorders
- HIV/AIDS oral health manifestations
- Sexuality, Behavior, and Technology
- Opioid Use Disorder Treatment
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS Impact and Responses
- Vaccine Coverage and Hesitancy
- Long-Term Effects of COVID-19
- Migration, Health and Trauma
- Poxvirus research and outbreaks
- COVID-19 Impact on Reproduction
Government of Catalonia
2016-2025
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2016-2025
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2016-2025
Instituto de Salud Carlos III
2011-2025
Universitat Autònoma de Barcelona
2016-2025
Centre for Omic Sciences
1998-2025
i2CAT
2023-2025
Departament de Salut
2014-2025
Comunidad de Madrid
1994-2025
Ministry of Health
2023-2024
Few studies have monitored late presentation (LP) of HIV infection over the European continent, including Eastern Europe. Study objectives were to explore impact LP on AIDS and mortality. was defined in Collaboration Observational Epidemiological Research Europe (COHERE) as diagnosis with a CD4 count <350/mm(3) or an within 6 months among persons presenting for care between 1 January 2000 30 June 2011. Logistic regression used identify factors associated Poisson AIDS/death. 84,524...
No effective treatments for coronavirus disease 2019 (COVID-19) exist. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be efficacious outpatients COVID-19.Multicenter open-label, randomized, controlled trial conducted in Catalonia, Spain, between 17 March and 26 May 2020. Patients recently diagnosed <5-day of symptom onset were assigned receive HCQ (800 mg on day 1 followed by 400 once daily 6 days) or usual care. Outcomes reduction viral load nasopharyngeal...
BackgroundCurrent strategies for preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited to nonpharmacologic interventions. Hydroxychloroquine has been proposed as a postexposure therapy prevent disease 2019 (Covid-19), but definitive evidence is lacking.MethodsWe conducted an open-label, cluster-randomized trial involving asymptomatic contacts of patients with polymerase-chain-reaction (PCR)–confirmed Covid-19 in Catalonia, Spain. We randomly assigned...
Most clinical guidelines recommend that AIDS-free, HIV-infected persons with CD4 cell counts below 0.350 × 10(9) cells/L initiate combined antiretroviral therapy (cART), but the optimal count at which cART should be initiated remains a matter of debate.To identify initiated.Prospective observational data from HIV-CAUSAL Collaboration and dynamic marginal structural models were used to compare initiation strategies for thresholds between 0.200 0.500 cells/L.HIV clinics in Europe Veterans...
To describe the CD4 cell count at start of combination antiretroviral therapy (cART) in low-income (LIC), lower middle-income (LMIC), upper (UMIC), and high-income (HIC) countries.Patients aged 16 years or older starting cART a clinic participating multicohort collaboration spanning 6 continents (International epidemiological Databases to Evaluate AIDS ART Cohort Collaboration) were eligible. Multilevel linear regression models adjusted for age, gender, calendar year; missing counts...
Background. Few studies consider the incidence of individual AIDS-defining illnesses (ADIs) at higher CD4 counts, relevant on a population level for monitoring and resource allocation.
Abstract Background The role of children in household transmission severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unclear. We describe the epidemiological and clinical characteristics with disease 2019 (COVID-19) Catalonia, Spain, investigate dynamics. Methods A prospective, observational, multicenter study was performed during summer school periods (1 July 2020–31 October 2020) to analyze features viral dynamics COVID-19 patients aged &lt;16 years. pediatric index...
Abstract Background Before the COVID-19 pandemic, Sexually transmitted infections (STIs) were increasing in Europe, and Spain Catalonia not an exception. has been one of regions with highest number confirmed cases Spain. The objective this study was to estimate magnitude decline, due STI during lockdown de-escalation phases. Methods Interrupted time series analysis performed decline reported - chlamydia, gonorrhoea, syphilis, lymphogranuloma venereum- since historical data, from March 13th...
Most countries have enacted some restrictions to reduce social contacts slow down disease transmission during the COVID-19 pandemic. For nearly two years, individuals likely also adopted new behaviours avoid pathogen exposure based on personal circumstances. We aimed understand way in which different factors affect - a critical step improving future pandemic responses.The analysis was repeated cross-sectional contact survey data collected standardized international study from 21 European...
We conducted a multicentric national study (SEIMC-CEME-22), to describe the clinical and epidemiological profile of mpox outbreak in Spain, including management disease.
The practice of using drugs to modulate experiences is a well-documented phenomenon worldwide, particularly among men who have sex with (MSM). This study aims describe patterns drug combinations used by Brazilian MSM, embracing detailed examination the context, which may inspire research elsewhere while enriching global panorama on MSM use. By focusing sheds light specific use combinations, help in development effective, culturally sensitive public health strategies. investigation was...
Background There is a co-occurrence of adolescents’ substance use and sexual practices, with an important impact on their health behaviours; however, limited research conducted adolescents. The aim this study was to estimate the prevalence (alcohol and/or other substances) in contexts identify its associated factors among adolescents, comparing boys girls. Methods Cross-sectional data from 6352 adolescents aged 14–18 years DESKcohort project. Prevalence alcohol (OSUSC) stratified by sex...
Abstract Background Health inequality in Latin America is particularly severe for individuals living with HIV (PLHIV) and key populations, such as men who have sex men, transgender women, people use drugs, workers. Despite regional programs aimed at reducing health inequalities, the Sustainable Development Goals Agenda Americas 2018–2030, COVID-19 crisis has exposed significant shortcomings national healthcare systems PLHIV populations. The multi-country, community-based research program,...
The advent of effective combination antiretroviral therapy (ART) in 1996 resulted fewer patients experiencing clinical events, so that some prognostic analyses individual cohort studies human immunodeficiency virus-infected individuals had low statistical power. Because this, the Antiretroviral Therapy Cohort Collaboration (ART-CC) HIV Europe and North America was established 2000, with aim studying prognosis for events acquired immune deficiency syndrome (AIDS) mortality adult treated HIV-1...
We compared Kaposi sarcoma (KS) risk in adults who started antiretroviral therapy (ART) across the Asia-Pacific, South Africa, Europe, Latin, and North America.
The aim of this study was to assess differences in the prevalence HIV and HCV infection associated risk factors between new (injecting for ≤5 years) long-term injectors estimate HIV/HCV incidence among injectors.Cross-sectional people who inject drugs (PWID) attended harm reduction centers Catalonia 2010-11. Anonymous questionnaires oral fluid samples were collected. Poisson regression models applied determine association factors.Of 761 participants, 21.4% injectors. New younger than (mean...
Abstract We aimed to identify risk factors for Kaposi's sarcoma (KS) among HIV‐positive patients and behaviors associated with human Herpesvirus 8 (HHV‐8) infection, as well assess KS incidence mortality rates longitudinally. To fulfill the first objective, a European case‐control study was designed in early 1990s (each case matched 2 controls another AIDS indicative disease). After discovery of HHV‐8, serology testing enabled us development HHV‐8 HIV‐1 coinfected men who have sex (MSM),...
To estimate the prevalence of HIV testing among patients diagnosed with an indicator condition (IC) for HIV, seen in primary care (PC) Catalonia, and to infection those patients.Cross-sectional population-based study aged between 16 65 IC within PC Catalonia.Data used this were extracted from a large public health database Spain, Information System Development Research Primary Care (SIDIAP). All participants registered SIDIAP 1 January 2010 31 August 2012 diagnosis screened identify test...
ABSTRACT Background Current strategies for preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are limited to non-pharmacological interventions. Hydroxychloroquine (HCQ) has been proposed as a postexposure therapy prevent Coronavirus disease 2019 (Covid-19) but definitive evidence is lacking. Methods We conducted an open-label, cluster-randomized trial including asymptomatic contacts exposed PCR-positive Covid-19 case in Catalonia, Spain. Clusters were...