Susana Monge
A5034034762- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS Research and Interventions
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- HIV Research and Treatment
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- HIV, Drug Use, Sexual Risk
- COVID-19 epidemiological studies
- Respiratory viral infections research
- COVID-19 Clinical Research Studies
- Data-Driven Disease Surveillance
- Pneumonia and Respiratory Infections
- COVID-19 and Mental Health
- Sex work and related issues
- Pneumocystis jirovecii pneumonia detection and treatment
- Migraine and Headache Studies
- Mosquito-borne diseases and control
- SARS-CoV-2 detection and testing
- Viral gastroenteritis research and epidemiology
- COVID-19 and healthcare impacts
- Hepatitis C virus research
- Viral Infections and Vectors
- Emergency and Acute Care Studies
- Migration, Health and Trauma
Instituto de Salud Carlos III
2009-2025
Centre for Biomedical Network Research on Rare Diseases
2013-2025
Centro de Investigación Biomédica en Red
2022-2025
Centro Nacional de Epidemiología
2011-2024
European Centre for Disease Prevention and Control
2018-2023
Ministry of Health
2020-2023
Ministerio de Ciencia, Innovación y Universidades
2022
Ministero della Salute
2021
Ministerio de Agricultura, Pesca y Alimentación
2021
National Institute for Public Health and the Environment
2018-2020
<h2>Summary</h2><h3>Background</h3> Antiretroviral therapy (ART) is crucial for controlling HIV-1 infection through wide-scale treatment as prevention and pre-exposure prophylaxis (PrEP). Potent tenofovir disoproxil fumarate-containing regimens are increasingly used to treat prevent HIV, although few data exist frequency risk factors of acquired drug resistance in regions hardest hit by the HIV pandemic. We aimed do a global assessment after virological failure with first-line...
We offer an overview of the COVID-19 -driven air quality changes across 11 metropolises in Spain with focus on lessons learned how continuing abating pollution. Traffic flow decreased by up to 80% during lockdown and remained relatively low full relaxation (June July). After a significant shift from public transport private vehicles (+21% Barcelona) persisted due pervasive fear that using might increase risk SARS-CoV-2 infection, which need be reverted as soon possible. NO2 levels fell below...
BackgroundRespiratory syncytial virus (RSV) causes substantial morbidity in infants < 1 year. In October 2023, Spain recommended the monoclonal antibody nirsevimab to all children born since April at birth or as catch-up if before 2023.AimWe estimated effectiveness preventing RSV hospitalisations during 2023/24 season.MethodsWe conducted a nationwide population-based matched case-control study. Cases were hospitalised for lower respiratory tract infection who PCR-positive. For each case, we...
High early mortality in patients with HIV-1 starting antiretroviral therapy (ART) sub-Saharan Africa, compared to Europe and North America, is well documented. Longer-term comparisons between settings have been limited by poor ascertainment of high burden African settings. This study aimed compare up four years on ART South Europe, America.Data from cohorts which lost follow-up (LTF) could be linked the national population register determine vital status were combined data America....
Residents in long-term care facilities (LTCF) experienced a large morbidity and mortality during the COVID-19 pandemic Spain were prioritised for early vaccination. We used screening method population-based data sources to obtain estimates of mRNA vaccine effectiveness elderly LTCF residents. The 71% (95% CI: 56–82%), 88% 75–95%), 97% 92-99%), against SARS-CoV-2 infections (symptomatic asymptomatic), hospitalisations deaths, respectively.
Effect estimates may be biased when the study design or data analysis is conditional on a collider—a variable that caused by two other variables. Causal directed acyclic graphs are helpful tool to identify colliders introduce selection bias in observational research.
With more than 7500 cases reported since April 2022, Spain has experienced the highest incidence of mpox in Europe. From 12 July onward, modified vaccinia Ankara-Bavaria Nordic (MVA-BN) smallpox vaccine was offered as pre-exposure prophylaxis for those receiving human immunodeficiency virus (HIV-PrEP). Our aim to assess effectiveness 1 dose MVA-BN against (MPXV) infection persons on HIV-PrEP.
Recent observational studies have found a higher risk of reinfection with the omicron variant SARS-CoV-2 in people who received third covid-19 booster dose. This finding has been interpreted as evidence immune imprinting vaccines. article proposes an alternative explanation: that increased individuals vaccinated compared no is result selection bias and expected to arise even absence imprinting. To clarify this explanation, describes how previous analyses were attempt estimate direct effect...
ABSTRACT Using a common protocol across seven countries in the European Union/European Economic Area, we estimated XBB.1.5 monovalent vaccine effectiveness (VE) against COVID‐19 hospitalisation and death booster‐eligible ≥ 65‐year‐olds, during October–November 2023. We linked electronic records to construct retrospective cohorts used Cox models estimate adjusted hazard ratios derive VE. VE for was, respectively, 67% (95%CI: 58–74) 42–81) 65‐ 79‐year‐olds 66% 57–73) 72% 51–85) 80‐year‐olds....
Human immunodeficiency virus type 1 (HIV-1) subtype may influence disease progression. We compared CD4 lymphocyte cell count levels at seroconversion, decline rates and viral load set point in individuals infected with different HIV-1 subtypes.We used data from the Concerted Action on SeroConversion to AIDS Death Europe (CASCADE) collaboration, restricted those since 1996, aged ≥15 years, applied mixed effects models for median regression (mean level 6-24 months seroconversion).The analysis...
Migrants are considered a key group at risk for HIV infection. This study describes the epidemiology of and distribution late presentation among migrants within European Union/European Economic Area during 2007-2012.HIV cases reported to Surveillance System (TESSy) were analyzed. defined as people whose geographical origin was different than reporting country. Multiple logistic regression used model presentation.Overall, 156,817 reported, which 60,446 (38%) migrants. Of these, 53% from...
ObjectivesTo analyze the impact of late presentation (LP) on overall mortality and causes death describe LP trends risk factors (2004–2013).MethodsCox models logistic regression were used to data from a nation-wide cohort in Spain. is defined as being diagnosed when CD4 < 350 cells/ml or AIDS.ResultsOf 7165 new HIV diagnoses, 46.9% (CI95%:45.7–48.0) LP, 240 patients died.First-year was highest (aHRLP.vs.nLP = 10.3[CI95%:5.5–19.3]); between 1 4 years post-diagnosis, aHRLP.vs.nLP 1.9(1.2–3.0);...
We conducted a registries-based cohort study of long-term care facility residents >65 years age offered vaccination against severe acute respiratory syndrome coronavirus 2 before March 10, 2021, in Spain. Risk for infection vaccinated and nonvaccinated persons was compared with risk the same period campaign, adjusted by daily-varying incidence reproduction number. selected 299,209 persons; 99.0% had >1 dose, 92.6% doses, 99.8% vaccines were Pfizer/BioNTech (BNT162b2). For no previous...
ABSTRACT Background Data from the sentinel surveillance system of severe acute respiratory infections in Spain were used to estimate impact administration nirsevimab children born 1 April 2023 onwards. Methods Estimated RSV hospitalisations < 1‐year‐olds during weeks 40, 2023, 8, 2024, compared number that would be expected after accounting for background change circulation 2023/24 season, 2022/23. Results We estimated 9364–9875 less than expected, corresponding a 74%–75% reduction.
Inverse probability weights used to fit marginal structural models are typically estimated using logistic regression. However, a data‐adaptive procedure may be able better exploit information available in measured covariates. By combining predictions from multiple algorithms, ensemble learning offers an alternative regression modeling further reduce bias model parameters. We describe the application of two approaches estimating stabilized weights: super (SL), machine approach that relies on...
We compared Kaposi sarcoma (KS) risk in adults who started antiretroviral therapy (ART) across the Asia-Pacific, South Africa, Europe, Latin, and North America.
This study compares the severity of SARS-CoV-2 infections caused by Alpha, Delta or Omicron variants in periods co-circulation Spain, and estimates variant-specific association vaccination with severe disease.
Introducción: Es esencial conocer la carga de enfermedad infección respiratoria aguda por Virus Respiratorio Sincitial (VRS) antes implementación cualquier medida preventiva. El objetivo este estudio es describir epidemiología VRS y estimar su en España a partir del Sistema Vigilancia Infección Respiratoria Aguda (SiVIRA). Método: Con datos SiVIRA se estimaron casos Atención Primaria hospitalizaciones VRS, grupo edad, las temporadas 2021-22 2022-23. Las estimadas con compararon altas...
Migrants are overrepresented in the European HIV epidemic. We aimed to understand barriers and facilitators testing current treatment healthcare needs of migrants living with Europe.A cross-sectional study was conducted 57 clinics nine countries (Belgium, Germany, Greece, Italy, The Netherlands, Portugal, Spain, Switzerland United Kingdom), July 2013 2015. HIV-positive patients were eligible for inclusion if they as follows: 18 years or older; foreign-born residents diagnosed within five...