A5072560978- Global Maternal and Child Health
- Emergency and Acute Care Studies
- Family and Patient Care in Intensive Care Units
- Antibiotic Use and Resistance
- Geriatric Care and Nursing Homes
- Child Nutrition and Water Access
- Healthcare Policy and Management
- Neonatal Respiratory Health Research
- Patient Satisfaction in Healthcare
- Primary Care and Health Outcomes
- Maternal and Neonatal Healthcare
- Healthcare Systems and Reforms
- Pneumonia and Respiratory Infections
- Infant Development and Preterm Care
- Global Health Workforce Issues
- Lysosomal Storage Disorders Research
- COVID-19 and healthcare impacts
- Glycogen Storage Diseases and Myoclonus
- Trypanosoma species research and implications
- Respiratory viral infections research
- Electronic Health Records Systems
- Palliative Care and End-of-Life Issues
- COVID-19 epidemiological studies
- Child and Adolescent Health
- Nursing education and management
Kenya Medical Research Institute
2016-2025
Wellcome Trust
2018-2025
University of Oxford
2023
London School of Hygiene & Tropical Medicine
2023
University of Amsterdam
2019-2021
Amsterdam University Medical Centers
2019-2020
University of Nairobi
2018
University of Maiduguri
2017
Moi University
2016
ObjectiveTo examine prescription patterns and explore to what extent guidelines are available how they might influence treatment appropriateness among hospitalised patients in Kenyan hospitals.MethodsData on antimicrobial usage were collected from across 14 public hospitals. For each prescription, of was defined using local international through consensus with medical specialists. Association between appropriate treatment, guideline availability other possible explanatory factors explored...
<title>Abstract</title> Limited or absent genetic counseling and testing resources in low- medium-income countries lead to missed late diagnoses for treatable metabolic conditions with irreversible complications. In some communities, misunderstanding about the etiology of a condition may women whose children are affected be viewed as bad omen become stigmatized ostracized from their community. Mucopolysaccharidosis type II (MPS II), Hunter syndrome, is lysosomal storage disorder which...
Reliable health information systems (HIS) are critical for effective decision-making in the delivery of Primary Health Care and Reproductive, Maternal, Newborn, Child, Adolescent Nutrition (PHC/RMNCAH+N) services. In Kenya, District Information Software 2 (DHIS2) platform serves as primary HIS tracking indicators. This study explored perceptions DHIS2 data quality use among PHC/RMNCAH+N stakeholders across 15 counties Kenya. A qualitative design was used, incorporating interviews with 88 key...
<title>Abstract</title> <bold>Background: </bold>Infection prevention and control (IPC) is a critical component of neonatal care, particularly in low- middle-income countries (LMICs), where healthcare settings face unique challenges. Neonates, especially preterm low birth-weight infants, are at higher risk for infections, including healthcare-associated infections. In Kenya, units struggle with limited resources, understaffing, shortages essential supplies, significantly impeding effective...
Asthma is a global health burden, with over 300 million people affected. Guidelines provide framework of reference by healthcare workers for the management and improvement care patients. The Ministry Health has provided Kenya Management to help reduce mortality morbidity asthma. This study assessed adherence national asthma guidelines short-term patient outcomes at Mama Lucy Kibaki Hospital (MLKH), identified barriers their implementation. A mixed-methods conducted included retrospective...
Audit and feedback (A&F) is widely used in healthcare but there are few examples of how to deploy it at scale low-income countries. Establishing the Clinical Information Network (CIN) Kenya provided an opportunity examine effect A&F delivered as part a wider set activities promote paediatric guideline adherence.We analysed data collected from medical records on discharge for children aged 2-59 months 14 Kenyan hospitals CIN. Hospitals joined CIN phases each we their initial 25 participation...
In Kenya, maternal and child health accounts for a large proportion of the expenditures made towards healthcare. It is estimated that one in every five Kenyans has some form insurance. Availability insurance may protect families from catastrophic spending on health. The study intended to determine factors affecting uptake among pregnant women rural Kenyan district.This was cross-sectional sampled 139 attending antenatal clinic at level 5 hospital district. information collected through...
Background Water Sanitation and Hygiene (WASH) in healthcare facilities is critical the provision of safe quality care. Poor WASH increases hospital-associated infections contributes to rise antimicrobial resistance (AMR). It therefore essential for governments hospital managers know state these set priorities allocate resources. Methods Using a recently developed survey tool scoring approach, we assessed across four domains 14 public hospitals Kenya (65 indicators) with specific assessments...
Pragmatic randomized trials aim to examine the effects of interventions in full spectrum patients seen by clinicians who receive routine care. Such should be employed parallel with efforts implement many which appear promising but where evidence effectiveness is limited. We illustrate this need taking case essential reduce inpatient neonatal mortality low and middle income countries (LMIC) suggest arguments are applicable most clinical areas. A set basic have been defined, based on available...
Essential interventions to reduce neonatal deaths that can be effectively delivered in hospitals have been identified. Improving information systems may support routine monitoring of the delivery these and outcomes at scale. We used cycles audit feedback (A&F) coupled with use a standardised newborn admission record (NAR) form explore potential for creating common inpatient data platform illustrate its prescribing accuracy. Revised NARs were introduced high volume, unit Kenya together 13 A&F...
### Summary box Antimicrobial resistance (AMR) is a significant public health threat that expected to worsen as more drug-resistant organisms emerge.1 This situation further exacerbated by the low rate of discovery new antimicrobial agents could act against micro-organisms. AMR retard economic growth in low-income countries and delay attainment sustainable development goals.2 There are multiple drivers AMR, but one key has been irrational use agents.3 In hospitals, lack timely accurate...
There are minimal data to define normal oxygen saturation (SpO<sub>2</sub>) levels for infants within the first 24 hours of life and even fewer generalisable 7% global population that resides at an altitude >1500 m. The aim this study was establish reference range SpO<sub>2</sub> in healthy term preterm neonates Nairobi, Kenya, located 1800 A random sample clinically well had measured once hours. total 555 were enrolled. 5th–95th percentile preductal postductal 89%–97% birthweight groups,...
<ns4:p><ns4:bold>Background: </ns4:bold>Infection prevention and control, water sanitation hygiene have an essential role in ensuring the quality of care patient outcomes hospitals. Using a modification World Health Organization’s facility improvement tool, we undertook assessments 14 public hospitals Kenya 2018. The received written feedback on areas where they could make improvements. Following first confirmed cases COVID-19 Kenya, were drawn to ask whether results our pre-pandemic survey...
Background Poor water sanitation and hygiene (WASH) in health care facilities increases hospital-associated infections, the resulting greater use of second-line antibiotics drives antimicrobial resistance. Recognising existing gaps, World Health Organisations' Water Sanitation for Facility Improvement Tool (WASH-FIT) was designed self-assessment. The tool small primary mainly providing outpatient limited inpatient not to compare hospital performance. Together with technical experts, we...
Attention has turned to improving the quality and safety of healthcare within health facilities reduce avoidable mortality morbidity. Interventions should be tested in system environments that can support their adoption if successful. To successful, interventions often require changes multiple behaviours making consequences unpredictable. Here, we focus on this challenge change at mesolevel or microlevel. Drawing insights from theory our own empirical work, highlight importance engaging...
Neonatal mortality remains significant in low-income and middle-income countries (LMICs) with in-hospital rates similar to those following discharge from healthcare facilities. Care continuity interventions have been suggested as a way of reducing postdischarge by better linking care between facilities communities. This scoping review aims map describe used LMICs improve for newborns after examine assumptions underpinning the design delivery continuity.