- Global Maternal and Child Health
- Primary Care and Health Outcomes
- Child Nutrition and Water Access
- Emergency and Acute Care Studies
- Healthcare Systems and Technology
- Data Stream Mining Techniques
- Privacy-Preserving Technologies in Data
- Caching and Content Delivery
- interferon and immune responses
- Soft tissue tumors and treatment
- Malaria Research and Control
- MRI in cancer diagnosis
- Respiratory and Cough-Related Research
- Breast Cancer Treatment Studies
- Pneumonia and Respiratory Infections
- Sepsis Diagnosis and Treatment
- Mosquito-borne diseases and control
- Hemoglobinopathies and Related Disorders
- Health Policy Implementation Science
- Cytomegalovirus and herpesvirus research
- Vascular Tumors and Angiosarcomas
- Trace Elements in Health
- Data-Driven Disease Surveillance
- Viral gastroenteritis research and epidemiology
- Infant Development and Preterm Care
Strathmore University
2025
University of Würzburg
2022
Kenya Medical Research Institute
2015-2019
Wellcome Trust
2016
In many low income countries health information systems are poorly equipped to provide detailed on hospital care and outcomes. Information is thus rarely used support practice improvement. We describe efforts tackle this challenge foster learning concerning collection use of information. This could improve services in Kenya. developing a Clinical Network, collaboration spanning 14 hospitals, policy makers researchers with the goal improving available quality inpatient paediatric across...
Management of pneumonia in many low-income and middle-income countries is based on WHO guidelines that classify children according to clinical signs define thresholds risk. We aimed establish whether some categorised as eligible for outpatient treatment might have a risk death warranting their hospital.
Background Lack of detailed information about hospital activities, processes and outcomes hampers planning, performance monitoring improvement in low-income countries (LIC). Clinical networks offer one means to advance methods for data collection use, informing wider health system development time, but are rare LIC. We report baseline from a new Information Network (CIN) Kenya seeking promote data-informed learning. Methods Data 13 hospitals engaged the Kenyan CIN between April 2014 March...
In 2002, we identified major shortcomings in the management of sick newborns and children at first referral or district hospital level Kenya.1 Failure dissemination knowledge skills (and thus translation evidence informed policy) was a fundamental problem. To address this challenge between 2005 2012 developed, implemented studied: 1. the national evidence-based clinical practice guidelines form protocol booklets that can be disseminated scale have recently described how process matured over...
Background Implementing small and sick newborn care (SSNC) requires skilled health workers; however, there is a shortage, adversely impacting patient outcomes worker well-being. There are limited data no current WHO standards for staff-to-baby ratios in neonatal units low- middle-income countries (LMICs) to inform policy, planning, investment. Methods In 65 (36 Malawi, 13 Kenya, 7 Tanzania, 9 Nigeria), facility assessment (HFA) SSNC government-led quality improvement (QI) processes were...
There is increasing focus on the strength of primary health care systems in low and middle-income countries (LMIC). are important roles for higher quality district hospital within these systems. These hospitals also sources information considerable importance to systems, but this role, as with wider hospitals, has been neglected. As we make efforts develop LMIC highlight critical focusing here how data mortality offers value: i) understanding disease burden; ii) part surveillance impact...
Severe anemia is a leading indication for blood transfusion and major cause of hospital admission mortality in African children. Failure to initiate rapidly enough contributes deaths sub-Saharan Africa. This article examines delays accessing outcomes transfused children Kenyan hospitals. Children admitted with nonsurgical conditions 10 county hospitals participating the Clinical Information Network who had ordered from September 2013 March 2016 were studied. The delay was calculated date...
Audit and feedback (A&F) is widely used in healthcare but there are few examples of how to deploy it at scale low-income countries. Establishing the Clinical Information Network (CIN) Kenya provided an opportunity examine effect A&F delivered as part a wider set activities promote paediatric guideline adherence.We analysed data collected from medical records on discharge for children aged 2-59 months 14 Kenyan hospitals CIN. Hospitals joined CIN phases each we their initial 25 participation...
An observational study of monitoring vital signs in children admitted to Kenyan hospitals: an insight into the quality nursing care?Background Measurement and correct interpretation is part routine clinical care.Repeated measurement enhances early recognition deterioration, may help prevent morbidity mortality a standard care most countries.Objective To examine documentation by clinicians for admissions paediatric wards hospitals, describe frequency nurses explore factors influencing...
Diarrhoea causes many deaths in children younger than 5 years and identification of risk factors for death is considered a global priority. The effectiveness currently recommended fluid management dehydration routine settings has also not been examined.
The World Health Organization (WHO) revised its clinical guidelines for management of childhood pneumonia in 2013. Significant delays have occurred during previous introductions new into routine practice low- and middle-income countries (LMIC). We therefore examined whether providing enhanced audit feedback as opposed to standard might accelerate adoption the by teams within hospitals a low-income setting. In this parallel group cluster randomized controlled trial, 12 were assigned either (n...
Up to 90 % of the global burden malaria morbidity and mortality occurs in sub-Saharan Africa children under-five bear a disproportionately high burden. Effective inpatient case management can reduce severe morbidity, but there are few reports how successfully international national recommendations adopted childhood malaria. A descriptive cross-sectional study practices was conducted using data collected over 24 months five hospitals from risk areas participating Clinical Information Network...
Abstract Objective To examine trends in prescription of cough medicines over the period 2002–2015 children aged 1 month to 12 years admitted Kenyan hospitals with cough, difficulty breathing or diagnosed a respiratory tract infection. Methods We reviewed hospitalisation records included four studies providing cross‐sectional prevalence estimates from government for six time periods between 2002 and 2015. Children an atopic illness were excluded. Amongst eligible children, we determined...
An audit of randomly selected case records 810 patients admitted to 13 hospitals between December 2015 and November 2016 was done. Prevalence dehydration 19.7% (2293 11 636) [95% CI: 17.1-22.6%], range across 9.4% 27.0%. Most cases with were clinically diagnosed (82 153; 53.6%), followed by excessive weight loss (54 35.3%) abnormal urea/electrolytes/creatinine (23 15.0%). Documentation fluids prescribed poor but, where data available, Ringers lactate (30 19.6%) 10% dextrose (18 11.8%) mostly...
Examining the effectiveness of zinc treatment in children admitted with diarrhoea Kenya's public hospitals: an observational comparative study Background Kenyan paediatric protocols recommend use supplement for all diarrhoea.However, there is limited evidence benefit young aged 1-5 months and those who are well-nourished.We examine supplementation to Kenya' s hospitals different nutritional age categories.This determine whether current policy where prescribed appropriate. MethodsWe explore...