A5057537033- Bone Tissue Engineering Materials
- Silk-based biomaterials and applications
- Osteoarthritis Treatment and Mechanisms
- Periodontal Regeneration and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Corneal Surgery and Treatments
- Collagen: Extraction and Characterization
- Proteoglycans and glycosaminoglycans research
- Food Quality and Safety Studies
- Tissue Engineering and Regenerative Medicine
- Analytical Methods in Pharmaceuticals
- Fungal Biology and Applications
- 3D Printing in Biomedical Research
- Drug Solubulity and Delivery Systems
- Ocular Surface and Contact Lens
- Retinal and Macular Surgery
- Spine and Intervertebral Disc Pathology
- Retinal Development and Disorders
- Polysaccharides Composition and Applications
- Dental Implant Techniques and Outcomes
- Medical Imaging and Analysis
- Polysaccharides and Plant Cell Walls
- Pharmacy and Medical Practices
- Chalcogenide Semiconductor Thin Films
- Healthcare and Venom Research
Jeonbuk National University
2016-2025
Korea Forest Service
2023
Catholic University of Daegu
2023
Seoul National University
2020-2021
Yonsei University
2017
Kangwon National University
2014-2016
Chonbuk National University Hospital
2012-2014
Yeouido St. Mary's Hospital
2013
Catholic University of Korea
2013
National University of Singapore
2013
Articular cartilage faces challenges in self-repair due to the lack of blood vessels and limited chondrocyte concentration. Polydeoxyribonucleotide (PDRN) shows promise for promoting growth regeneration, but its delivery has been injections. Continuous PDRN is crucial effective regeneration. This study explores using gelatin methacrylate (gelMA) hydrogel, crosslinked with visible light riboflavin 5′-phosphate sodium (RF) as a photoinitiator, sustained release. GelMA hydrogel’s synthesis was...
There is a significant rise in the bone grafts demand worldwide to treat defects owing continuous increase conditions such as injury, trauma, diseases, or infections. Therefore, development of three-dimensional scaffolds has evolved reliable technology address current limitations for tissue regeneration. Mimicking natural bone, this study, we have designed silk fibroin/hydroxyapatite scaffold inlaid with bioactive phytochemical (quercetin) at different concentrations promoting osteogenesis,...
Exosomes (EXs) are nanocarrier vesicles with 20-50 nm dimensions. They involved in cell proliferation and differentiation protecting the integrity of materials. can be isolated from plasma immunoreactive components. Recent studies demonstrated their potential role cartilage regeneration. To enhance regenerative effect, molecules like microRNA (miR-140) loaded EX that acts as RNA delivery systems. In this study, we combined miR-140 to by inducing membrane fusion consequent miRNA released into...
This study investigated the influence of pore sizes poly(lactic-co-glycolic acid) (PLGA) scaffolds on compressive strength tissue-engineered biodiscs and selection best suitable size for cells to grow in vivo. PLGA were fabricated by solvent casting/salt-leaching with 90-180, 180-250, 250-355 355-425 µm. Nucleus pulposus (NP) seeded various sizes. Each sample was harvested at each time point, after retrieval NP cells, which implanted into subcutaneous spaces nude mice 4 6 weeks. MTT assay,...
Treating critical-sized bone defects is an important issue in the field of tissue engineering and regeneration. From various biomaterials for regeneration, collagen widely used biomaterial biomedical applications, hence, it has numerous attractive properties including biocompatibility, hyper elastic behavior, prominent mechanical properties, support cell adhesion, proliferation, biodegradability. In present study, was extracted from duck's feet (DC) as a new source combined with quercetin...
Shape-memory polymers (SMPs) can be defined as a reversibly changing form through deformation and recovery by external stimuli. However, there remain application limitations of SMPs, such complicated preparation processes slow shape recovery. Here, we designed gelatin-based shape-memory scaffolds facile dipping method in tannic acid solution. The effect was attributed to the hydrogen bond between gelatin acid, which acts net point. Moreover, (Gel)/oxidized gellan gum (OGG)/calcium chloride...
Scrub typhus, a disease caused by Orientia tsutsugamushi, triggers systemic vasculitis and is prevalent in Eastern Southern Asia. This study aimed to uncover the relationship between scrub typhus autoimmune responses, focusing on antinuclear antibodies (ANAs) implications of elevated ANA titers during infection. Data from total 139 patients diagnosed with 30 healthy controls were retrospectively analyzed through serum samples assess levels ANAs related autoantibodies. The further examined...
Abstract Cu 2 ZnSn(S,Se) 4 (CZTSSe) thin‐film solar cells offer various advantages including excellent optical and electrical properties, nontoxic earth‐abundant raw materials, a simple fabrication process. However, these devices suffer from high deficit of the open‐circuit voltage ( V OC ), mainly caused by interface recombination, which increases with increasing surface roughness. In this study, to achieve enhance overall device performance, an additional heat treatment process was...
Herein, an injectable thermosensitive hydrogel was developed for a drug and cellular delivery system. The composite prepared by facile physical mixing of pluronic F-127 (PF) silk fibroin (SF) in aqueous solution. chemical structure, transparency, viscosity, injectability, degradation kinetic, cumulative release dexamethasone (Dex), type corticosteroid drug, size distribution the fabricated hydrogels were characterized. Cytotoxicity also studied to verify biocompatibility hydrogels. addition...
Polysaccharides isolated from the fruiting body of Inonotus obliquus (PFIO) are known to possess various pharmacological properties including antitumor activity. However, anti-metastatic effect and its underlying mechanistic signaling pathway involved these polysaccharides in human non-small cell lung carcinoma remain unknown. The present study therefore aimed determine potential pathways PFIO highly metastatic A549 cells. We found that suppressed migration invasive ability cells while...
Cornea endothelial cells (CEnCs) tissue engineering is a great challenge to repair diseased or damaged CEnCs and require an appropriate biomaterial support cell proliferation differentiation. Biomaterials for biocompatibility, tunable biodegradability, transparency, suitable mechanical properties. Silk fibroin-based film (SF) known meet these factors, but construction of functionalized graft bioengineering cornea still challenge. Herein, lysophosphatidic acid (LPA) used maintain increase the...
The cellular transplantation approach to treat damaged or diseased retina is limited because of poor survival, distribution, and integration cells after implantation the sub-retinal space. To overcome this, it important develop a cell delivery system. In this study, ternary hydrogel gelatin (Ge)/gellan gum (GG)/glycol chitosan (CS) suggested as carrier for retinal tissue engineering (TE). Physicochemical properties such porosity, swelling, sol fraction, weight loss were measured. mechanical...