- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- vaccines and immunoinformatics approaches
- Circular RNAs in diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Immune Response and Inflammation
- Adenosine and Purinergic Signaling
- Quinazolinone synthesis and applications
- interferon and immune responses
- Glaucoma and retinal disorders
- Lung Cancer Diagnosis and Treatment
- Retinopathy of Prematurity Studies
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Inflammasome and immune disorders
- Extracellular vesicles in disease
- Intraocular Surgery and Lenses
University of California, Los Angeles
2025
Emory University
2019-2021
Atlanta VA Health Care System
2020
The University of Texas Southwestern Medical Center
2014
Nontuberculous Mycobacteria (NTM) are a heterogeneous group of environmental microorganisms with distinct human pathogenesis. Their incidence and prevalence rising worldwide, due in part to elevated antimicrobial resistance which complicates treatment potential successful outcomes. Although information exists on the clinical significance NTMs, little is known about host immune response infection. NTM infections alter macrophage mitochondrial capacity decrease ATP production, efficient...
Purpose: To report demographic and ocular features of pediatric glaucoma suspects in an ethnically diverse population North Central Texas. Design: Retrospective cross-sectional chart review. Participants: Subjects included 75 (136 eyes) suspects. Patients with one or more the following risk factors were included: cup-to disc (C/D) ratio ≥0.6; intraocular pressure (IOP) ≥21 mmHg; family history glaucoma; congenital opposite eye; blunt trauma to either presence Sturge–Weber Axenfeld–Rieger...
Non-tuberculous mycobacteria (NTM) have been recognized as a causative agent of various human diseases, including severe infections in immunocompromised patients, such people living with HIV. The most common species identified is the Mycobacterium avium-intracellulare complex (MAI/MAC), accounting for majority infections. Despite abundant information detailing clinical significance NTM, little known about host–pathogen interactions NTM infection. MicroRNAs (miRs) serve important...
P. aeruginosa is an opportunistic pathogen and a significant contributor of recalcitrant multidrug resistant infections. Immunocompromised hospitalized patients are especially susceptible to rapid incessant Therapies modulating innate immune defenses the host urgently needed for managing We have previously shown that respiratory epithelium important defense against it's (quorum sensing) QS molecule N‐3‐oxo‐dodecanoyl‐L‐Homoserine lactone (C12‐HSL). Infection with PAO1 as well C12‐HSL...