Background: Candida species are a leading cause of fungal infections worldwide. Candidiasis, the disease caused by Candida, represents significant public health concern globally. albicans is most common causative agent, responsible for 50 - 90% invasive candidiasis cases. employs various virulence factors to adhere to, invade host tissues, and disease. Objectives: This study aimed detect compare C. albicans, including hydrophobicity, biofilm formation, ergosterol content, secretory enzymes,...

Oral candidiasis (OC) is one of the most common opportunistic fungal infections among people living with HIV/AIDS (PLWHA). The prevalence OC and Candida profiles HIV-infected patients might be changing in era Highly Active Antiretroviral Therapy (HAART). This study aimed to identify spp., determine associated risk factors for PLWHA.Oral was explored oral swabs 276 who referred consultation at Behavioral Diseases Counseling Center (BDCC). Clinical symptoms, culture molecular assays were used...

Diabetes mellitus as a chronic metabolic disease occurs in patients with partial or complete deficiency of insulin secretion disorder action on tissue. The is known to provide conditions for overgrowth Candida species. spp. cause candidiasis by many virulence factors such esterase, hemolysin and phospholipase.This study aimed compare esterase hemolytic activity various species isolated from oral cavity diabetic non-diabetic individuals.Swab samples were taken 95 diabetes (35 men 60 women)...

Background and Purpose:Ozone is an inorganic molecule with effective antimicrobial properties.Clinical treatment of ozonated water was used for the elimination Candida albicans, Enterococcus faecalis, endotoxins, biofilms from root canals.In addition, its therapeutic effects tinea pedis, ulcers, leishmaniasis were investigated.The purpose present study to evaluate fungicidal ozone on different forms C. albicans.In antifungal susceptibility profile strains assessed before after exposure...

Resistance to azole drugs has been observed in candidiasis due their long-term use and poor response treatment. Candida albicans isolates is controlled by several genes including ERG11, CDR1, CDR2, MDR1. In this study, the expression of mentioned was evaluated C. susceptible resistant fluconazole.After identifying using morphological molecular methods, minimum inhibitory concentration (MIC) drug susceptibility were determined European Committee on Antimicrobial Susceptibility Testing...

Background: Oral candidiasis is a common disease in cancer patients subject to chemotherapy. The aim of this study was evaluate the risk factors rising oral incidence and identify Candida species isolated from lesions their antifungal sensitivity. Materials Methods: A total 645 with were examined. Several specimens identified by morphological molecular methods. susceptibility isolates amphotericin B, fluconazole, nystatin also investigated. Results: 74 recovered cavity 61 candidiasis....

Onychomycosis is fungal infection of the nails with an overall increasing incidence, worldwide. The epidemiological aspects onychomycosis in Khuzestan, Iran, have not been established. In this study, we aimed to evaluate clinical and mycological status nail Khuzestan Province, Iran.The study population included 433 patients (143 males vs. 290 females). Nail samples underwent primary direct microscopy culture. isolated yeasts dermatophytes were then subjected additional molecular...

Oropharyngeal candidiasis is one of the most common opportunistic fungal infections among human immunodeficiency virus (HIV)-infected individuals. The cause Candida albicans, followed by non-albicans Candida. This study aimed to identify colonized species in HIV-infected patients from Ahvaz, Iran. Additionally, relationships between immunity-related factors, lifestyle, and colonization spp. were studied.Oral swabs taken 201 HIV-positive referred for consultations at Behavioral Modification...

Black Aspergillus strains including, niger and A. tubingensis, are the most cause of otomycosis with worldwide distribution. Although, amphotericin B was a Gold standard for treatment invasive fungal infection several decades, it gradually replaced by fluconazole /or voriconazole. Moreover, luliconazole, appears to offer best potential in vitro activity against black strains. The aim present study compare commonly used antifungals clinical environmental Aspergillus.Sixty seven (37 30...

Abstract Yeast species are a group of coexistent microorganisms in the oral cavity that can cause opportunistic infections vulnerable individuals, including addicts. This study aimed to identify yeast profile responsible for colonization (OYC) and associated risk factors patients with substance use disorder (SUD) Ahvaz, Iran. Oral samples were collected from drug users hospitalized 12 addiction treatment centers, related clinical information was mined. identified using 21-plex PCR sequencing...

Allergens from Fusarium solani Identified by Immunoblotting in Asthma Patients In Iran We extracted antigens to evaluate specific anti- F. IgE fifty-one patients with asthma (33 men and 18 women) 22 non-atopic healthy subjects (15 7 women). strains were cultured Sabouraud glucose agar subjected cell disruption using the freeze-and-thaw method. The obtained cytoplasmic extracts analysed sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). Sensitisation has been evaluated...

Background: Black walnut (Juglans nigra) is known to have antimicrobial and antifungal effects in vitro. Objectives: This study aimed compare the of extracts derived from green-husked with clotrimazole against Candida albicans female rats. Methods: In this study, 35 Wistar rats were randomly assigned 5 groups. A total 4 groups infected vaginally C. 1 group was not (negative control). The received following treatments: 2 vaginal creams containing 2% or 4% J. nigra extracts, respectively, 1%...

Ozone is an inorganic molecule with effective antimicrobial properties. Clinical treatment of ozonated water was used for the elimination Candidaalbicans, Enterococcus faecalis, endotoxins, and biofilms from root canals. In addition, its therapeutic effects tinea pedis, ulcers, leishmaniasis were investigated. The purpose present study to evaluate fungicidal ozone on different forms C. albicans. antifungal susceptibility profile strains assessed before after exposure ozone.Fifty albicans...

Abstract Objective: To evaluate the prevalence of Candida species in cancer patients with candidemia around world, and to identify related risk factors their antifungal resistance, an emphasis on non-albicans (NACs). Methods: The published papers subject were systematically searched databases MEDLINE (including PubMed), Web Science, Scopus, Science Direct, Google Scholar between 1 st January 2000 21 April 2021. Results: Among 4 546 records, 69 studies met inclusion criteria. pooled NACs was...

Oral candidiasis (OC) is the most frequent opportunistic fungal infection, which a predictive indicator of immunosuppression and disease progression among people living with HIV/AIDS (PLWHA). In present study, 109 Candida isolates were collected from 94 PLWHA afflicted oral infection (OCI) following highly active antiretroviral therapy (HAART). The susceptibility profiles Candidaspp. to six antifungal agents evaluated using CLSI broth microdilution. prevalence OCI was 34.06%. profile...

Propolis is known to have biological properties against numerous microorganisms of clinical interest. This important, because all Candida krusei (C. krusei) isolates are resistant azole drugs. The aims this study were determine the chemical composition and antifungal efficacy Iranian propolis C. strains isolated from patients with cutaneous mucosal candidiasis. Ethanolic extract (EEP) was prepared originating Mazandaran province, submitted analysis by high-resolution gas chromatography...

Systemic candidiasis is an opportunistic infection caused by Candida species in animals. The purpose of this study was to evaluate the pathogenicity different doses zeylanoides BALB/c mice. Thirty mice were selected study. Different yeast intravenously inoculated At first, clinical signs and survival time infected recorded. Then both mycological histological examinations performed for detection tissues. results showed that injection 1 × 10^8 cells C. high mortality (group 1). mortalities...

Background: Invasive fungal infections acquired in the hospital have progressively emerged as an important cause of life-threatening infection. In particular, airborne fungi hospitals are considered critical pathogens hospital-associated infections. Objectives: This study aimed to investigate indoor environments educational city Ahvaz, Iran. Methods: The air samples were taken from seven wards five using Quick Take 30 sample pump. A total 175 cultured into Sabouraud dextrose agar and...

Background: Candida yeast is a normal flora of the mucous membrane oral cavity. Various enzymes secreted by species play role virulence factors in different infections including cancer patients. Objectives: This study aimed at comparing phospholipase, proteinase, esterase, and hemolytic activities isolated from cavity patients people. Methods: was conducted on 36 healthy MspI restriction enzyme for PCR-RFLP method used to identify species. The enzymatic activity index (EAI) measured each...

Biofilm is an accumulation of cells, which are formed on mucosal surfaces the host as well medical devices. The inherent resistance Candida strains producing biofilms to antimicrobial agents important and key feature for biofilm growth, can lead treatment failure. This due regulatory increase output pumps, presence extracellular matrix, existence persister cells. Persister cells phenotypic variants that have MICs similar antibiotic-sensitive populations able tolerate high doses antibiotics....