A5057013326- Pain Management and Placebo Effect
- Pain Mechanisms and Treatments
- Empathy and Medical Education
- Memory and Neural Mechanisms
- Neural and Behavioral Psychology Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Pediatric Pain Management Techniques
- Neuroscience, Education and Cognitive Function
- Heart Rate Variability and Autonomic Control
- Stress Responses and Cortisol
- Olfactory and Sensory Function Studies
- Neural dynamics and brain function
- Complementary and Alternative Medicine Studies
- Sleep and Wakefulness Research
- Vestibular and auditory disorders
- Psychosomatic Disorders and Their Treatments
- Neuroscience and Neuropharmacology Research
- Mental Health and Psychiatry
- Mindfulness and Compassion Interventions
- Acupuncture Treatment Research Studies
- COVID-19 and Mental Health
- Musculoskeletal pain and rehabilitation
- Pharmacology and Obesity Treatment
- Diet and metabolism studies
- Traumatic Brain Injury Research
Norwegian University of Science and Technology
2014-2024
UiT The Arctic University of Norway
2005-2020
Christie's
2006-2012
American Society for Investigative Pathology
2011
Ministry of Education and Research
2011
University Hospital of North Norway
2003
University of Bergen
1989-1991
Objective Administration of the muscle relaxant carisoprodol and placebo was crossed with information that agonistic or antagonistic to effect carisoprodol. It investigated whether alone induced physiological psychological responses, modified response drug. Methods Half subjects received capsules containing 525 mg together drug acted in a specific way (Groups Relaxant/C, Stimulant/C, No Information/C). The other half lactose Relaxant/L, Stimulant/L, Information/L). Dependent variables were...
Several studies have shown that male subjects report lower pain intensity to female compared experimenters. The present experiment examined whether experimenter gender also modulated autonomic responses. Sixty-four students (32 females) participated in a 2 Subject × Experimenter 15 Pain Tests mixed design. Six experimenters, three females and males collected data. Heat was +48 °C induced the right volar forearm. Subjective measurements consisted of intensity, unpleasantness, stress, arousal...
To examine whether there are gender differences in event-related potential (ERP) responses to painful stimulation after administration of placebo medication; and investigate medication reduces anticipatory stress if this reduction can explain the analgesic response. Several experimental clinical studies have shown that males report lower pain compared with females. There are, however, few reports analgesia.All subjects (n = 33; 17 women) participated both a natural history condition. ERPs...
Abstract The human startle response is modulated by emotional experiences, with potentiation associated negative affect. We used positron emission tomography 15 O‐water to study neural networks modulation phobic fear in a group of subjects specific snake or spider phobia, but not both, during exposure pictures their feared and non‐feared objects, paired unpaired acoustic stimuli. Measurement eye electromyographic activity confirmed the as compared non‐phobic condition. Employing factorial...
To examine whether reduction of negative emotions and associated autonomic activity could explain placebo analgesia, to test the effect experimenter gender on analgesic response.Sixty-three (n = 32 females) students participated in a within-subjects design where subjects were tested two separate days, one day for experimental condition (placebo) natural history condition. In condition, participants received capsules containing lactose with information that high dose potent painkiller....
Fear of pain (FOP) and its effect on placebo analgesia was investigated. It hypothesized that FOP should interfere with placebo-mediated inhibition result in weaker responding intensity, unpleasantness, stress, event-related potentials to contact heat pain. Thirty-three subjects participated a balanced 2 condition (natural history, placebo)×3 test (pretest, posttest 1, 2) within-subject design, tested separate days. measured by the Pain Questionnaire subjective stress Short Adjective Check...
TOC summary Induced fear abolished placebo analgesia in reported pain intensity and the acoustic startle reflex, this effect was strongest subjects highest self-reported fear. Fear induced by anticipation of electric shock order to investigate whether reduced effectiveness a intervention on reflex. Thirty-three participated 3 Condition (Natural History [NH], Placebo [P], + [PF]) × Test (Pretest, Posttest 1, 2) within-subject design, tested separate days. Measures were (FOP), measured Pain...
Objective The experiment tested whether the placebo and nocebo responses could be mediated via modulation of stress. Methods Ischemic pain was induced in healthy volunteers (N = 59). When reached "7" on a 10-point scale, two groups subjects received information that relieving (the Placebo group) or increasing Nocebo substance injected. All injections contained physiological saline. A third group no injection Natural History group). Pain ratings blood samples for analysis cortisol...
Abstract Background and aim Despite recent publications, practitioners remain unfamiliar with the current terminology related to placebo nocebo phenomena observed in clinical trials practice, nor factors that modulate them. To cover gap, European Headache Federation appointed a panel of experts clarify terms associated use trials. Methods The working group identified relevant questions agreed upon recommendations. Because no data were required answer questions, GRADE approach was not...
Abstract Several methods of quantifying prepulse inhibition (PPI) eyeblink responding were compared in adult volunteers. Blink‐eliciting stimuli noise bursts at 85 or 100 dB, and prepulses also bursts, 55 70 dB lead intervals 60 120 ms. PPI was evaluated by comparing reactivity on control trials within participants using the following methods: (1) difference between trials; (2) divided that (proportion control); (3) trials, from (4) range correction (maximum minus minimum reactivity,...
In a randomised placebo-controlled clinical trial it is assumed that psychosocial effects of the treatment, regression to mean and spontaneous remission are identical in drug placebo group. Consequently, any difference between groups can be ascribed pharmacological effects. Previous studies suggest side drugs enhance expectancies treatment group compared group, thereby increase responses The hypothesis was tested. Painful laser stimuli were delivered 20 healthy subjects before after...