A5009462648- Cell Image Analysis Techniques
- Single-cell and spatial transcriptomics
- Image Processing Techniques and Applications
- 3D Printing in Biomedical Research
- Biomimetic flight and propulsion mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Physiological and biochemical adaptations
- Advanced Fluorescence Microscopy Techniques
- Zebrafish Biomedical Research Applications
Broad Institute
2019-2023
Boston College
2018
Abstract Segmenting the nuclei of cells in microscopy images is often first step quantitative analysis imaging data for biological and biomedical applications. Many bioimage tools can segment but need to be selected configured every experiment. The 2018 Data Science Bowl attracted 3,891 teams worldwide make attempt build a segmentation method that could applied any two-dimensional light image stained across experiments, with no human interaction. Top participants challenge succeeded this...
Abstract Image-based profiling has emerged as a powerful technology for various steps in basic biological and pharmaceutical discovery, but the community lacked large, public reference set of data from chemical genetic perturbations. Here we present generated by Joint Undertaking Morphological Profiling (JUMP)-Cell Painting Consortium, collaboration between 10 companies, six supporting two non-profit partners. When completed, dataset will contain images profiles Cell assay over 116,750...
Forums and email lists play a major role in assisting scientists using software. Previously, each open-source bioimaging software package had its own distinct forum or list. Although provided access to experts from various teams, this fragmentation resulted many not knowing where begin with their projects. Thus, the scientific imaging community lacked central platform solutions could be discussed an open, software-independent manner. In response, we introduce Scientific Community Image...
The skin of aquatic vertebrates surrounds all the mechanical lineages body and must, therefore, play an important role in locomotion. A cross‐woven collagenous dermal design has converged across several clades vertebrates. Despite this intriguing pattern, biomechanical swimming fishes remains largely unknown. direct force transmission for fish been proposed, a hypothesis that is supported by arrangement connective tissues linking to axial musculature. To evaluate force‐transmission...