A5101878707- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Advanced Algorithms and Applications
- Antibiotics Pharmacokinetics and Efficacy
- Vector-borne infectious diseases
- Nanoparticle-Based Drug Delivery
- Carbon Dioxide Capture Technologies
- Urinary Tract Infections Management
- Autoimmune and Inflammatory Disorders Research
- Acute Kidney Injury Research
- Peripheral Neuropathies and Disorders
- Thermochemical Biomass Conversion Processes
- Ubiquitin and proteasome pathways
- Studies on Chitinases and Chitosanases
- Power Systems and Renewable Energy
- Protein Interaction Studies and Fluorescence Analysis
- Education and Work Dynamics
- Coal and Its By-products
- Coal Combustion and Slurry Processing
- Coal Properties and Utilization
- Antibiotic Resistance in Bacteria
- Electric and Hybrid Vehicle Technologies
- Nanoplatforms for cancer theranostics
- Iron and Steelmaking Processes
- Effects of Radiation Exposure
University of Electronic Science and Technology of China
2024
First Affiliated Hospital of Anhui Medical University
2023
Anhui Medical University
2023
Fudan University
2019-2021
Nanjing University of Chinese Medicine
2019-2020
Jiangsu Province Hospital
2019-2020
Guangzhou Center for Disease Control and Prevention
2013-2020
Nanjing Library
2019
Anhui Business College
2009-2013
Sun Yat-sen University
2011-2012
Environmental antibiotic resistance genes (ARGs) have received much attention, while the characteristics of ARGs carried by particulate matter (PM) as a function urban functional region are almost unknown. In this study, PM2.5 and PM10 in an hospital, nearby community nearest suburban were detected using metagenomics. total, 643 ARG subtypes belonging to 22 different types identified. The chloramphenicol exporter gene, sul1, bacA, lnuA most abundant all air samples. hospital exhibited higher...
Podophyllotoxin (PPT), a toxic polyphenol extracted from the roots of Podophyllum species, showed remarkable activity against P-glycoprotein (P-gp) mediated multidrug resistant (MDR) cancer cells. Many PPT-prodrugs based on nano-technology have been developed for increasing aqueous solubility and reducing side effects PPT; however, sensitive linkers in almost all were ester bonds, resulting slow incomplete drug release. We redox/pH double-sensitive tumor active targeted delivery system PPT...
The re-emergence of dengue virus 4 (DENV-4) has become a public health concern in South America, Southeast Asia and Asia. However, it not been known to have caused local outbreak China for the past 20 years. purpose this study was elucidate epidemiology one community by DENV-4 Guangzhou city, China, 2010; determine molecular characteristics genotype II involved.During September October 2010, imported case, resident who travelled back from Thailand, resulted 18 secondary autochthonous cases...
Multidrug resistance (MDR) of cancer cells is a significant challenge in chemotherapy, highlighting the urgent medical need for simple and reproducible strategies to reverse this process. Here, we report development an active tumor-targeting redox-responsive nanoplatform (PA-ss-NP) using hyaluronic acid-g-cystamine dihydrochloride-poly-ε-(benzyloxycarbonyl)-L-lysine (HA-ss-PLLZ) co-deliver paclitaxel (PTX) apatinib (APA) effective reversal MDR. This smart specifically bound CD44 receptors,...
After an absence of 29 years, dengue virus type 3 (DENV-3) re-emerged in Guangzhou 2009 and again 2010. However, the geographical route by which entered city, how it has changed genetically, remain unclear. Therefore, we carried out a comprehensive investigation into molecular characteristics DENV-3 involved.The envelope (E) genes viruses isolated from patients during 2009-2010 epidemics were sequenced compared with previously published E gene sequences global representative strains...
Co-combustion of coal and natural gas is a promising technology in the production active lime.For this technology, proper fuel proportion (α) one key parameters that requires significant thought.By means numerical simulation, contrast studies on co-combustion with five different proportions were carried out.This paper firstly puts forward models used to describe system based actual conditions.Then, simulation results analysed detail illustrate process velocity temperature distribution...
In this paper, the energy consumption and its distribution of forklift in various working conditions are analyzed through experiments, main factors found, which can find a breakthrough for system saving provide theoretical basis subsequent research. According to measured battery output voltage current electric forklift, walking accounts about 42.7% overall hydraulic system, steering 13% pitch 0.3% lifting largest proportion reaching 44%.
LYSC98 is a vancomycin derivative used for gram-positive bacterial infections therapy. We reported the pharmacokinetic/pharmacodynamic (PK/PD) targets of against Staphylococcus aureus using murine thigh infection model. Three strains were utilized. Single-dose plasma pharmacokinetics determined in infected mice after tail vein injection 2, 4, and 8mg/kg. The results showed maximum concentration (C max ) 11466.67 - 48866.67 ng/mL, area under concentration-time curve from 0 to 24 h(AUC 0-24...