- Congenital Heart Disease Studies
- Renal and related cancers
- Tumors and Oncological Cases
- Congenital Diaphragmatic Hernia Studies
- Sexual Differentiation and Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Sperm and Testicular Function
- Intestinal Malrotation and Obstruction Disorders
- Cardiomyopathy and Myosin Studies
- Congenital Anomalies and Fetal Surgery
- Pediatric Urology and Nephrology Studies
- Hedgehog Signaling Pathway Studies
- Cytomegalovirus and herpesvirus research
- Airway Management and Intubation Techniques
- Cancer and Skin Lesions
- Tracheal and airway disorders
- Cardiac Valve Diseases and Treatments
- MicroRNA in disease regulation
- Neonatal Respiratory Health Research
- Liver Disease Diagnosis and Treatment
- Teratomas and Epidermoid Cysts
- Thyroid Cancer Diagnosis and Treatment
- Testicular diseases and treatments
- RNA regulation and disease
IILM Institute for Higher Education
2021-2023
Children's National
1992-2004
George Washington University
1984-2001
Washington University Medical Center
1980-2001
Inoue Hospital
2001
National Institutes of Health
1976-1998
National Cancer Institute
1987-1998
Brigham and Women's Hospital
1995
Harvard University
1995
University of Miami
1994
Early reports of pediatric HIV-1-associated neuropathology described the presence viral particles in some astrocytes, implicating direct infection immature nervous system as a contributing factor to observed neuropathology. Several recent suggest that those astrocytes infected with HIV-1, level antigenic expression proviral genome is below sensitivity limits conventional histochemical techniques. Identification these would instead require use highly sensitive radiolabeled DNA or RNA probe...
PURPOSE: To compare the sensitivity and specificity of technetium-99m dimercaptosuccinic acid (DMSA) single photon emission computed tomography (SPECT), spiral (CT), magnetic resonance (MR) imaging, power Doppler ultrasonography (US) for detection localization acute pyelonephritis by using histopathologic findings as standard reference. MATERIALS AND METHODS: Bilateral vesicoureteric reflux was surgically created in 35 piglets (70 kidneys). One week later, a liquid bacterial culture...
No AccessJournal of Urology1 Nov 1988Evaluation 99Mtechnetium-Dimercapto-Succinic Acid Renal Scans in Experimental Acute Pyelonephritis Piglets H. Gil Rushton, Massoud Majd, Roma Chandra, and Dae Yim RushtonH. Rushton More articles by this author , MajdMassoud Majd ChandraRoma Chandra YimDae View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)41992-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We evaluated...
We have developed methods to use anticyclin A, B, and E antibodies as reagents specifically detect proliferating cells in specific phases of the cell cycle formalin-fixed, paraffin-embedded sections tissues cells. Staining 48 archival cases breast cancer showed that these estimate tumor proliferation fraction therefore are potentially useful for prediction prognosis. A subset cancers had a high frequency expressing cyclins E, out proportion other markers, suggesting tumors may deregulated...
Solid and papillary epithelial neoplasms of the pancreas from six female patients were studied using immunohistochemistry electron microscopy to define better their histogenesis. The tumors ranged in diameter 5 15 cm (average: 9 cm), and, on cross section, most had areas hemorrhage necrosis, sometimes extensive. Microscopically, there was a solid pseudopapillary pattern, with tumor cells typically having ovoid nuclei delicate folding indistinct nucleoli. Of note following: relatively low...
The differential diagnoses of childhood and adolescent tumors composed small round cells include a distinctive clinicopathological entity called malignant cell tumor (MSCT) the thoracopulmonary region in childhood. In present study, 15 such that fulfilled criteria by Askin et al. were examined for features possible neural differentiation light electron microscopy (EM). With hematoxylin-eosin stain (H&E) made up undifferentiated cells; rosette formation was noticed four cases. By...
Brain heterotopias are rare congenital malformations embryologically related to encephaloceles. They present as a mass in or about the nose (nasal glioma) nasopharynx. We clinical and pathological features of 5 cases heterotopic brain tissue. Four nasal gliomas consisted mature neuroglial tissue, including neurons 2 cases, embedded fibrovascular stroma. A nasopharyngeal heterotopia showed histologic tissue ependymal-lined cystic structures. The finding from head neck region raises three...
A varicocele is a common cause of adult male infertility, and surgical ligation generally accepted mode therapy. However, the guidelines for management adolescent with are not clearly defined. Herein, we describe histologic abnormalities noted on testis biopsy in nine 24 boys moderate to large varicoceles. Surgical recommended when there volume loss ipsilateral varicocele. All others should be reexamined periodically, an attempt made obtain baseline semen analysis.
The immunocompetence of six infants with the clinical form Letterer-Siwe disease and seven older children in various phases histiocytosis was evaluated. In most patients, delayed hypersensitivity, lymphocyte blastogenesis to mitogens allogeneic cells, bactericidal killing, leukocyte nitroblue tetrozolium dye reduction were found be within normal limits. One patient infantile one child could not sensitized DNFB. lymphocytes from two hyporeactive mitogeninduced stimulation. This reverted after...
Barakat, A. Y., Papadopoulou, Z. L., Chandra, R. S., Hollerman, C. E., and Calcagno, P. L.: Pseudohermaphroditism, nephron disorder, Wilms' tumor: A unifying concept. Pediatrics, 54:366, 1974. The authors inadvertently omitted to credit Figure 3 (p. 368) Dr. Robert W. Miller.
A newborn infant with cardiac failure resulting from a rhabdomyoma of the left ventricle obstructing aortic outflow tract is described. Mild subvalvular pulmonary stenosis was also present because tumor in ventricular septum. Tuberous sclerosis occurs at least half infants such tumors and pathologically this child, although not apparent clinically. Rhabdomyomas must be considered differential diagnosis heart disease may associated tuberous even when nervous system cutaneous signs are present.
Five children were noted to have arteriohepatic dysplasia (Alagille's syndrome) between 3 and 7 months of age. Prior diagnosis, four underwent Kasai procedures after intraoperative cholangiograms failed demonstrate patency the extrahepatic bile ducts. In three patients, a focal proximal hypoplasia common hepatic duct was demonstrated with fibrosis increased vascularity. Hypoplasia gallbladder occurred in two patients. Changes observed porta hepatis. Eighty 208 micrometers ducts associated...