A5023048261- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Urinary Tract Infections Management
- Urinary Bladder and Prostate Research
- Congenital gastrointestinal and neural anomalies
- Kidney Stones and Urolithiasis Treatments
- Ureteral procedures and complications
- Testicular diseases and treatments
- Pelvic floor disorders treatments
- Urologic and reproductive health conditions
- Ethics and Legal Issues in Pediatric Healthcare
- Urinary and Genital Oncology Studies
- Bladder and Urothelial Cancer Treatments
- Tissue Engineering and Regenerative Medicine
- Congenital Anomalies and Fetal Surgery
- Spinal Dysraphism and Malformations
- Renal and Vascular Pathologies
- Neonatal Health and Biochemistry
- Childhood Cancer Survivors' Quality of Life
- Anorectal Disease Treatments and Outcomes
- Genital Health and Disease
- Adolescent and Pediatric Healthcare
- Sexual Differentiation and Disorders
- Diverticular Disease and Complications
- Hernia repair and management
Children's National
2016-2025
George Washington University
2009-2024
National Hospital
2021
Henry Ford Hospital
2014
The University of Texas Southwestern Medical Center
2002-2011
Oregon Health & Science University
2011
American Urological Association
2010
Harvard University
2002-2005
Boston Children's Hospital
2003-2005
Hospital for Sick Children
2004
Children with febrile urinary tract infection commonly have vesicoureteral reflux. Because trial results been limited and inconsistent, the use of antimicrobial prophylaxis to prevent recurrences in children reflux remains controversial.
Clinical dogma is that healthy urine sterile and the presence of bacteria with an inflammatory response indicative urinary tract infection (UTI). Asymptomatic bacteriuria (ABU) represents state in which are present but negligible. Differentiating ABU from UTI diagnostically challenging, critical because overtreatment can perpetuate antimicrobial resistance while undertreatment result increased morbidity mortality. In this study, we describe key characteristics microbiomes utilizing 16S rRNA...
OBJECTIVES: To identify risk factors for recurrent urinary tract infection (UTI) and renal scarring in children who have had 1 or 2 febrile symptomatic UTIs received no antimicrobial prophylaxis. METHODS: This 2-year, multisite prospective cohort study included 305 aged to 71 months with vesicoureteral reflux (VUR) receiving placebo the RIVUR (Randomized Intervention Vesicoureteral Reflux) 195 VUR observed CUTIE (Careful Urinary Tract Infection Evaluation) study. Primary exposure was...
PURPOSE: To compare the sensitivity and specificity of technetium-99m dimercaptosuccinic acid (DMSA) single photon emission computed tomography (SPECT), spiral (CT), magnetic resonance (MR) imaging, power Doppler ultrasonography (US) for detection localization acute pyelonephritis by using histopathologic findings as standard reference. MATERIALS AND METHODS: Bilateral vesicoureteric reflux was surgically created in 35 piglets (70 kidneys). One week later, a liquid bacterial culture...
Tumor registries, urological textbooks and literature surveys all assert that yolk sac tumors are the most common primary testicular in boys 12 years younger. In contrast, several individual institutions have reported benign more than malignant tumors. To clarify these discordant findings, we surveyed pathology records from 4 major pediatric centers.The of contributing centers were culled for masses Older those with either paratesticular or leukemia excluded. The prevalence each histological...
Little generalizable information is available on the outcomes of children diagnosed with bladder and bowel dysfunction (BBD) after a urinary tract infection (UTI). Our objectives were to describe clinical characteristics BBD examine effects patient in without vesicoureteral reflux (VUR).We combined data from 2 longitudinal studies (Randomized Intervention for Children With Vesicoureteral Reflux Careful Urinary Tract Infection Evaluation) which <6 years age first or second UTI followed years....
A child's health, positive perceptions of the research team and consent process, altruistic motives play significant roles in decision-making process for parents who their child to enroll clinical research. This study identified that nonconsenting were better educated, had private insurance, showed lower levels altruism, less understanding design.To determine factors associated with parental participation a randomized, placebo-controlled trial.Cross-sectional survey conducted from July 2008...
Purpose: Compared to the microbiome of other body sites, urinary remains poorly understood. Although noninvasive voided urine specimens are convenient, contamination by urethral microbiota may confound understanding bladder microbiome. Herein we compared voiding- versus catheterization-associated healthy men and women.Methods: An asymptomatic, cohort 6 women 14 underwent midstream collection, followed sterile catheterization after refilling. Urine samples dipstick testing conventional...
We isolated multipotential mesenchymal stem cells (MSC) from human postnatal dermal tissues. The were expanded and maintained for over 100 population doublings with retention of their chromosomal complement potential multilineage differentiation. Progeny cell lines established a single MSC could be differentiated into adipogenic, osteogenic, myogenic lineages, consistent the conclusion that we clonal, multipotential, somatic line. This study is first to show growth can used engineering...
We determined parental preferences for the treatment of vesicoureteral reflux in their child.Parents children with were prospectively recruited to evaluate choices management. In each case a standard questionnaire that described options was administered. Parents asked choose between long-term antibacterial prophylaxis annual radiography studies and open or endoscopic at 1 5 years followup. They also given choice treatment. Annual resolution and/or correction rates provided medical, surgical...
We used the PathoScope platform to perform species level analyses of publicly available, 16S rRNA pyrosequenced, asymptomatic urine data determine relationships between microbiomes, and clinical functional phenotypes.We reanalyzed previously reported, cross-sectionally acquired samples from 47 subjects, including 23 controls 24 subjects with neuropathic bladder. Urine was originally collected by usual method bladder drainage analyzed urinalysis, culture pyrosequencing. Urinalysis values were...
Children in whom nonsurgical management for vesicoureteral reflux fails are considered candidates surgical intervention. An option is endoscopic treatment with Deflux(R). We reviewed our experience febrile urinary tract infections children following initial successful of Deflux and identified factors predictive post-Deflux infections. also analyzed the incidence delayed recurrence these patients.We performed a retrospective chart review all from 2002 to 2006 diagnosed grades I IV who were...
We sought to define features that describe the dynamic information in diuresis renograms for early detection of clinically significant hydronephrosis caused by ureteropelvic junction obstruction.We studied renogram 55 patients with a mean ± SD age 75 66 days who had congenital at initial presentation. Five bilaterally affected kidneys total 60 renograms. Surgery was performed on 35 kidneys. extracted 45 based curve shape and wavelet analysis from drainage curves recorded after furosemide...
No AccessJournal of UrologyPEDIATRIC UROLOGY1 Jul 2001PARENTAL PREFERENCES IN THE MANAGEMENT OF VESICOURETERAL REFLUX KENNETH OGAN, HANS G. POHL, DORIS CARLSON, A.B. BELMAN, and H.G. RUSHTON OGANKENNETH OGAN , POHLHANS POHL CARLSONDORIS CARLSON BELMANA.B. BELMAN RUSHTONH.G. View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)66135-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We...
No AccessJournal of UrologyObstruction1 Jun 2001EARLY DIURESIS RENOGRAM FINDINGS PREDICT SUCCESS FOLLOWING PYELOPLASTY HANS G. POHL, H. GIL RUSHTON, JAE-SHIN PARK, A. BARRY BELMAN, and MASSOUD MAJD POHLHANS POHL , RUSHTONH. RUSHTON PARKJAE-SHIN PARK BELMANA. BELMAN MAJDMASSOUD View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)66192-7AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose:...
Ureteroceles have traditionally been managed surgically. We report our indications and outcomes of nonoperative management ureteroceles in a select cohort.We identified prospectively for 11 females 2 males with associated hydronephrosis or multicystic dysplasia (MCD). Patients presented either febrile urinary tract infection (3) prenatal (10). All patients were evaluated renal bladder ultrasound, voiding cystourethrography mercaptoacetyltriglycine-3 furosemide renography. Two subgroups...
The evaluation of children presenting with urinary tract infection (UTI) has long entailed sonography and cystography to identify all urological abnormalities that might contribute morbidity. identification vesicoureteral reflux (VUR) been primary concern since retrospective studies from the 1930s 1960s established a strong association between VUR, recurrent UTI, renal cortical scarring. It proposed VUR carries risk for scarring and, therefore, should be identified treated. We will not...