A5020564993- Neuroscience and Neuropharmacology Research
- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Parkinson's Disease Mechanisms and Treatments
- Electrohydrodynamics and Fluid Dynamics
- Surface Modification and Superhydrophobicity
- Power Transformer Diagnostics and Insulation
Centre National de la Recherche Scientifique
2020-2023
Université de Bordeaux
2020-2023
Institut des Maladies Neurodégénératives
2020
The basal ganglia (BG) inhibit movements through two independent circuits: the striatal neuron-indirect and subthalamic nucleus-hyperdirect pathways. These pathways exert opposite effects onto external globus pallidus (GPe) neurons, whose functional importance as a relay has changed drastically with discovery of distinct cell types, namely prototypic arkypallidal neurons. However, little is known about synaptic connectivity scheme different GPe neurons toward both motor-suppressing pathways,...
When a high voltage is applied between two beakers filled with deionized water, floating bridge of water formed in exceeding the length 2 cm when are pulled apart. Currently theories regarding stability exist, one suggesting that tension caused by electric field dielectric medium holding and other surface to be responsible for vertical equilibrium. We construct experiments which geometry measured compared predictions stability. use numerical simulation estimation field. Our results indicate...
Excessive oscillatory activity across basal ganglia (BG) nuclei in the β frequencies (12-30 Hz) is a hallmark of Parkinson's disease (PD). While link between oscillations and symptoms remains debated, exaggerated constitute an important biomarker for therapeutic effectiveness PD. The neuronal mechanisms -oscillation generation however remain unknown. Many existing models rely on central role subthalamic nucleus (STN) or cortical inputs to BG. Contrarily, neural recordings optogenetic...
Abstract Basal ganglia (BG) inhibit movement through two independent pathways, the indirect- and hyperdirect-pathways. The globus pallidus (GP) has always been viewed as a simple relay within these but its importance changed drastically with discovery of functionally-distinct cell types, namely prototypic arkypallidal neurons. Classic BG models suggest that all GP neurons receive GABAergic inputs from striato-pallidal indirect spiny projection glutamatergic subthalamic However, whether this...
Excessive oscillatory activity across basal ganglia (BG) nuclei in the β frequencies (12–30Hz) is a hallmark of Parkinson’s disease (PD). While link between oscillations and symptoms remains debated, exaggerated constitute an important biomarker for therapeutic effectiveness PD. The neuronal mechanisms β- oscillation generation however remain unknown. Many existing models rely on central role subthalamic nucleus (STN) or cortical inputs to BG. Contrarily, neural recordings optogenetic...