A5108156516- Analytical Chemistry and Sensors
- Analytical chemistry methods development
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Water Quality Monitoring and Analysis
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Chemical Sensor Technologies
- Analytical Chemistry and Chromatography
- Analytical Methods in Pharmaceuticals
- Innovative Microfluidic and Catalytic Techniques Innovation
- Ionic liquids properties and applications
- Antibiotics Pharmacokinetics and Efficacy
- Electrical and Bioimpedance Tomography
- Pesticide Residue Analysis and Safety
- Intravenous Infusion Technology and Safety
- Mycotoxins in Agriculture and Food
- Advanced biosensing and bioanalysis techniques
- Flow Measurement and Analysis
- RNA Interference and Gene Delivery
- Vibrio bacteria research studies
- Mercury impact and mitigation studies
- Antibiotic Use and Resistance
- Per- and polyfluoroalkyl substances research
- Statistical Methods in Clinical Trials
- Ultrasound and Cavitation Phenomena
Universidade do Porto
2009-2025
Rede de Química e Tecnologia
2007-2025
Universidade Federal da Paraíba
2000
Universidade Federal de Pernambuco
1999
Deep eutectic solvents (DESs), a novel class of eco-friendly solvents, are attracting considerable attention in extraction techniques. In this study, hydrophobic DES, created by combining quaternary ammonium salt and hexanoic acid, was coated onto commercial cellulose membrane for polycyclic musks (cashmeran, celestolide, galaxolide, tonalid) microextraction from surface waters followed gas-chromatography–mass spectrometry (GC MS) analysis. A series DESs were synthesized characterized to...
Endocrine-disrupting contaminants (EDCs) encompass а wide variety of organic chemicals that have the capacity to disrupt normal functioning endocrine system, thereby causing adverse health effects. Evaluating EDCs levels in water and food is critical determine risk these chemical pose. In recent years, a range analytical methods been proposed for determination based on green chemistry principles. This review presents an overview application deep eutectic solvents (DESs) sample preparation...
Pharmacokinetic (PK) studies improve the design of dosing regimens in preclinical and clinical settings. In complex diseases like cancer, single-agent approaches are often insufficient for an effective treatment, drug combination therapies can be implemented. this work, silico PK models were developed based on vitro assays results, with goal predicting vivo performance combinations context cancer therapy. Combinations reference drugs gemcitabine 5-fluorouracil (5-FU), repurposed...
The construction and evaluation of an electrode selective to perchlorate with improved sensitivity, constructed like a conventional (ISE), but using operational amplifier sum the potentials supplied by four membranes (ESOA) is described. two types electrodes, without inner reference solution, were octylammonium chloride as sensor, mixture dibutylphthalate o-nitrophenyloctyl ether solvent mediator PVC plastic matrix, being obtained direct application onto conductive epoxy resin support. After...
Gemcitabine is an anticancer drug used to treat a wide range of solid tumors and first line treatment for pancreatic cancer. Our group has previously developed novel conjugates gemcitabine with cell-penetrating peptides (CPP), here we report some preliminary data regarding the pharmacokinetics gemcitabine, two gemcitabine-CPP respective CPP gathered from GastroPlus™, analyze these results considering our previous evaluation release conjugates’ bioactivity. Additionally, seeking shed light on...
Diacetyl can be determined by adsorptive stripping voltammetry after derivatization with o-phenylenediamine. The method may applicable to the determination of diacetyl in different foods, being a good alternative other analytical methods. In this work an on-line automated system for beer is described. A hanging mercury drop electrode voltammetric flow detector was used, and analyte without traditional deoxygenation procedure. successfully applied during fermentation final product. automation...
A sequential injection analysis (SIA) system for the simultaneous determination of nitrite, nitrate, sulphate and phenolic compounds, in wastewaters has been developed.The nitrite is based on Griess-Llosvay reaction.Nitrate previously reduced to a copperized cadmium column analyzed as nitrite.The turbidimetric using barium chloride reagent.The compounds oxidative coupling with 4-aminoantipyrine (4-AAP) alkaline solution.The resulting products each reaction were spectrophotometrically...
A sequential injection analysis system based on the formation of cation FeSO4+ and spectrophotometric measuring absorbance at 355 nm has been developed for determination sulphate in wastewaters. The main interferents were also evaluated. proposed is fully automatized able to monitor samples. relative standard deviation (RSD) obtained was smaller than 2.4%. linearity response between 10 1000 mg L-1. sampling rate 72 samples per hour.