A5103255284- Neuroscience and Neuropharmacology Research
- Memory and Neural Mechanisms
- Blood Pressure and Hypertension Studies
- Posttraumatic Stress Disorder Research
- Medication Adherence and Compliance
- Chronic Disease Management Strategies
- Digital Mental Health Interventions
- Behavioral Health and Interventions
- Statistical Methods and Bayesian Inference
- Psychosomatic Disorders and Their Treatments
- Diverse Approaches in Healthcare and Education Studies
- Child Abuse and Trauma
- Healthcare Education and Workforce Issues
- Homelessness and Social Issues
- ECG Monitoring and Analysis
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Migration, Health and Trauma
- Obsessive-Compulsive Spectrum Disorders
- Health and Wellbeing Research
- Statistical Methods and Inference
- Mobile Health and mHealth Applications
- Tryptophan and brain disorders
- Ophthalmology and Visual Health Research
- Healthcare professionals’ stress and burnout
- Pharmaceutical Practices and Patient Outcomes
Ralph H. Johnson VA Medical Center
2012-2023
Medical University of South Carolina
2012-2023
Yale University
2009
Drug craving is an important motivational phenomenon among addicted individuals, and successful management of essential to both the initiation maintenance abstinence. Although in response drug cues common drug‐dependent it not universal. At present time, known why approximately 20–30% all persons fail report appreciable laboratory‐based cue reactivity studies. This study examined possibility that alexithymia, a personality attribute characterized by difficulty identifying describing...
Background Based on preclinical studies showing that the partial N ‐methyl‐D‐aspartate (NMDA) agonist D‐cycloserine (DCS) facilitates extinction of cocaine self‐administration and cocaine‐induced conditioned place preference, we evaluated whether 50 mg DCS would reduce craving to cues when combined with cue exposure (CE) in dependent humans. Methods In this double‐blind placebo‐controlled pilot study, 47 participants were randomized or placebo (PBO), plus CE. Participants received PBO 30...
Background and Objectives A growing literature provides evidence for the use of integrated treatments (e.g., Concurrent Treatment PTSD Substance Use Disorders Using Prolonged Exposure; COPE); however, no known studies have applied COPE via telehealth. Method was delivered telehealth to treat one black female veteran with combat trauma alcohol disorder. Results The patient demonstrated significant reductions in consumption depressive symptoms. Conclusions Scientific Significance Although...
Continuous outcomes with preponderance of zero values are ubiquitous in data that arise from biomedical studies, for example studies addictive disorders. This is known to lead violation standard assumptions parametric inference and enhances the risk misleading conclusions unless managed properly. Two-part models commonly used deal this problem. However, two-part have limitations respect obtaining parameter estimates marginal interpretation covariate effects which important many applications....