A5055665031- Smoking Behavior and Cessation
- Cannabis and Cannabinoid Research
- Stress Responses and Cortisol
- Substance Abuse Treatment and Outcomes
- Neuroendocrine regulation and behavior
- Prenatal Substance Exposure Effects
- Atherosclerosis and Cardiovascular Diseases
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Child and Adolescent Psychosocial and Emotional Development
- Neurotransmitter Receptor Influence on Behavior
- Advanced Glycation End Products research
- Behavioral Health and Interventions
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes and associated disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Attention Deficit Hyperactivity Disorder
- Nicotinic Acetylcholine Receptors Study
- Chronic Kidney Disease and Diabetes
- Neuroscience and Neuropharmacology Research
- Neural and Behavioral Psychology Studies
- Neuroscience of respiration and sleep
- Memory and Neural Mechanisms
- Bipolar Disorder and Treatment
- Transcranial Magnetic Stimulation Studies
- Tryptophan and brain disorders
Medical University of South Carolina
2016-2025
Ralph H. Johnson VA Medical Center
2011-2024
MUSC Hollings Cancer Center
2023-2024
OSF Saint Francis Medical Center
2024
Peoria campus of the University of Illinois System
2024
University of South Carolina
2023
College of Charleston
2012-2018
University of California, Irvine
2015
New York University
2015
Medical College of Wisconsin
2015
<h3>Objective:</h3> We examined whether individual neuronal architecture obtained from the brain connectome can be used to estimate surgical success of anterior temporal lobectomy (ATL) in patients with lobe epilepsy (TLE). <h3>Methods:</h3> retrospectively studied 35 consecutive TLE who underwent ATL. The structural was reconstructed all using presurgical diffusion MRI. Network links were standardized as <i>Z</i> scores based on connectomes healthy controls. topography abnormalities...
The objective of this study was to examine the modifying effect gender on association between early life trauma and hypothalamic-pituitary-adrenal (HPA) axis response a pharmacologic challenge social stress task in men women. Participants (16 men, 23 women) were control sample larger examining HPA function. Individuals with major depressive disorder, posttraumatic bipolar or psychotic eating disorders excluded.In two test sessions, subjects received 1 µg/kg corticotropin-releasing hormone...
OBJECTIVE High cholesterol levels in circulating immune complexes (IC), surrogate markers of modified LDL, are associated with increased carotid intima-media thickness (IMT) and cardiovascular events type 1 diabetes. Different modifications LDL involved IC formation, but which these predictive vascular is not known. Therefore, we measured oxidized (oxLDL), advanced glycation end products–modified (AGE-LDL), malondialdehyde-modified (MDA-LDL) determined their relationship IMT compared the...
The purpose of this article is to correlate various ultrasound features breast cancer with tumor grade, and estrogen, progesterone, ERRB2 (formerly HER2) receptor status as well assess the predictive value these features.The cancers found by using between January 2010 June 2011 were reviewed for size, margins, posterior acoustic features. margins classified into spiculated, angular, indistinct, lobulated or microlobulated, circumscribed. shadowing, enhancement, mixed pattern, no change....
<h3>Importance</h3> Recent research on addiction-related memory processes suggests that protracted extinction training following brief cue-elicited retrieval (ie, retrieval-extinction [R-E] training) can attenuate/eradicate the ability of cues to elicit learned behaviors. One study reported craving among detoxified heroin addicts was substantially attenuated R-E and through 6-month follow-up. <h3>Objective</h3> To build these impressive findings by examining whether could attenuate...
Background and Objectives Recent evidence suggests that women may fare worse than men in cannabis trials with pharmacologic interventions. Identifying baseline clinical profiles of treatment-seeking cannabis-dependent adults could inform gender-specific treatment planning development. Methods The current study compared demographic, use, psychiatric factors between (n = 86) 216) entering the Achieving Cannabis Cessation−Evaluating N-acetylcysteine Treatment (ACCENT) study, a multi-site,...
The current study aimed to determine in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Interventions cohort whether or not abnormal levels markers inflammation endothelial dysfunction measured samples collected at DCCT baseline were able predict development macroalbuminuria.Levels cell biomarkers 1,237 1,441 patients enrolled who both free albuminuria cardiovascular disease baseline. To test association log-transformed with albuminuria, generalized logistic regression...
This survey study assesses trends in nicotine use among young adults the US between 2013 and 2021.
To determine whether immunocomplexes (ICs) containing advanced glycation end product (AGE)-LDL (AGE-LDL) and oxidized LDL (oxLDL) contribute to the development of retinopathy over a 16-year period in subjects with type 1 diabetes.Levels AGE-LDL oxLDL ICs were measured 517 patients Diabetes Control Complications Trial/Epidemiology Interventions (DCCT/EDIC) cohort. Retinopathy was assessed by stereoscopic fundus photography. Cox proportional hazards models used assess effect AGE-LDL-ICs...
Background: Adverse childhood experiences (ACEs) show a graded association with the development of substance use disorders (SUDs) and engagement in risky behaviors. Women are overrepresented among individuals more severe adversity (≥4 types ACEs) may be at particular risk for aberrant use.Objectives: To assess prevalence ACEs men women cannabis, opioid, cocaine, tobacco disorders.Methods: Non-treatment-seeking participating clinical addiction research single site completed ACE questionnaire...
Craving for methamphetamine is commonly reported by heavy users of the drug and may increase risk relapse in newly abstinent individuals. Exposure to methamphetamine-associated cues laboratory can elicit measureable craving autonomic reactivity some individuals with dependence. In this study, clinical demographic correlates optimal conditions its measurement are explored.Subjective (craving) physiologic (heart rate skin conductance) presentation photo, video, paraphernalia were evaluated 43...