A5050412209- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Astro and Planetary Science
- Atmospheric aerosols and clouds
- Atmospheric Ozone and Climate
- Advanced X-ray and CT Imaging
- Planetary Science and Exploration
- Head and Neck Cancer Studies
- Atmospheric chemistry and aerosols
- Ionosphere and magnetosphere dynamics
- Advanced MRI Techniques and Applications
- Radiation Effects and Dosimetry
- Parkinson's Disease Mechanisms and Treatments
- Geomagnetism and Paleomagnetism Studies
- Urban Transport and Accessibility
- Radiation Detection and Scintillator Technologies
- Effects of Radiation Exposure
- Surgical Simulation and Training
- Ocular Surface and Contact Lens
- Neurobiology of Language and Bilingualism
- Augmented Reality Applications
- Retinal and Macular Surgery
- Wireless Body Area Networks
University of Canterbury
2015-2024
Canterbury District Health Board
2021
Aecom (United Kingdom)
2012
Christchurch Hospital
2010-2011
University of Oxford
2009-2010
National Institute of Water and Atmospheric Research
2009
The extent to which Alzheimer neuropathology, particularly the accumulation of misfolded beta-amyloid, contributes cognitive decline and dementia in Parkinson's disease (PD) is unresolved. Here, we used Florbetaben PET imaging test for any association between cerebral amyloid deposition impairment PD, a sample enriched cases with mild impairment. This cross-sectional study Movement Disorders Society level II criteria classify 115 participants PD as having normal cognition (PDN, n = 23),...
Existing knowledge on cycling behavior, as with travel behavior in general, is based mainly cross-sectional studies. It questionable how much can be learned about the reasons for behavioral change from such A major investment program to promote 12 English cities and towns between 2008 2011 provided opportunity study bicycle use of residents that was affected by investment. Face-to-face interviews collected biographical information life-change events during period 144 research participants...
Abstract. The Global Retrieval of ATSR Cloud Parameters and Evaluation (GRAPE) project has produced a global data-set cloud aerosol properties from the Along Track Scanning Radiometer-2 (ATSR-2) instrument, covering time period 1995–2001. This paper presents validation optical depths (AODs) over ocean this product against AERONET sun-photometer measurements, as well comparison to Advanced Very High Resolution Radiometer (AVHRR) depth by Aerosol Climatology Project (GACP). GRAPE AOD is found...
Abstract. This study examines the utility of Empirical Mode Decomposition (EMD) time-series analysis technique to separate horizontal wind field observed by Scott Base MF radar (78° S, 167° E) into its constituent parts made up mean wind, gravity waves, tides, planetary waves and instrumental noise. Analysis suggests that EMD effectively separates a set Intrinsic Functions (IMFs) which can be related atmospheric with different temporal scales. The resultant from application Monte-Carlo...
We describe the New Zealand Parkinson's Progression Programme (NZP3), its goals, findings, and future plans. To date, 354 people with disease 89 healthy older controls have participated over a 14-year period. A major focus of programme has been characterisation current cognitive impairment, identification biomarkers for emergence in Parkinson's. The made significant contributions to concept mild impairment (MCI) development validation standardised criteria it. Brain imaging, both MRI PET,...
Background and purposeReduced toxicity while maintaining loco-regional control rates have been reported after reducing planning target volume (PTV) margins for head-and-neck radiotherapy (HNRT). In this context, quantifying anatomical changes to monitor patient treatment is preferred. This retrospective feasibility study investigated the application of deformable image registration (DIR) Exponentially Weighted Moving Average (EWMA) Statistical Process Control (SPC) charts purpose.Materials...
The combined effects of lung tumor motion and limitations treatment planning system dose calculations in regions increases uncertainty delivered to the surrounding normal tissues stereotactic body radiotherapy (SBRT). This study investigated effect on plan quality accuracy when overriding volume electron density values. QUASAR phantom with modified cork cylindrical inserts, each containing a simulated spherical 15-mm, 22-mm, or 30-mm diameter, was used simulate motion. Using Monaco 5.1...
Digital holographic interferometry (DHI) radiation dosimetry has been proposed as an experimental metrology technique for measuring absorbed doses to water with high spatial resolution via noninvasive optical calorimetry. The process involves digitally recording consecutive interference patterns resulting from variations in the refractive index a function of radiation-absorbed dose. Experiments conducted on prototype systems revealed approach be feasible but strongly dependent...
Abstract. The aerosol component of the Oxford-Rutherford Aerosol and Cloud (ORAC) combined cloud retrieval scheme is described theoretical performance algorithm analysed. ORAC an optimal estimation for deriving properties from measurements made by imaging satellite radiometers and, when applied to free radiances, provides estimates optical depth at a wavelength 550 nm, effective radius surface reflectance nm. has several incarnations – this paper addresses version which operates in...
Internal lead shielding is utilized during superficial electron beam treatments of the head and neck, such as lip carcinoma. Methods for predicting backscattered dose include use empirical equations or performing physical measurements. The accuracy these required verification local beams. In this study, a Monte Carlo model Siemens Artiste linac was developed 6, 9, 12, 15 MeV beams using EGSnrc MC package. verified against measurements to an better than 2% 2 mm. Multiple simulations...
Abstract. The Global Retrieval of ATSR Cloud Parameters and Evaluation (GRAPE) project has produced a global data-set cloud aerosol properties from the Along Track Scanning Radiometer-2 (ATSR-2) instrument, covering time period 1995–2001. This paper presents validation optical depths (AODs) this product against AERONET sun-photometer measurements, as well comparison to Advanced Very High Resolution Radiometer (AVHRR) depth by Aerosol Climatology Project (GACP). GRAPE AOD over ocean is found...
Purpose: To investigate the dosimetric effects of collimator material on spatially modulated proton minibeams (pMBRT). Methods : pMBRT holds promise to exhibit shallow depth normal‐tissue sparing similar synchrotron based microbeams while also retaining potential for uniform dose distributions tumor targets. TOPAS Monte Carlo simulations were performed a 5cm thick multislit with 0.3mm slits and 1mm center‐to‐center spacing 50.5MeV minibeam varying between brass, tungsten, iron. The was...
Simulations of physical processes and behavior can provide unique insights understanding real-world problems. Magnetic Resonance Imaging (MRI) is an imaging technique with several components complexity. Several these have been characterized simulated in the past. However, computational challenges prevent simulations from being simultaneously fast, flexible, accurate.
T1rho imaging has been used to probe relatively slow macromolecular processes, making it a practical tool gain information about water spin dynamics and interactions with endogenous macromolecules. We measured the dispersion of different spin-lock fields in intervertebral disc swine spine specimens before after treatment induce proteoglycan loss, sign early degeneration. Analysis revealed elevated values all proteoglycan-depleted discs at each field, that post-treatment changes increase higher field.
The Medipix All Resolution Scanner (MARS) spectral CT is intended for small animal, pre-clinical imaging and uses an x-ray detector (Medipix) operating in single photon counting mode. MARS system provides spectrometric information to facilitate differentiation of tissue types bio-markers. For longitudinal studies disease models, it desirable characterise the system's dosimetry. This dosimetry study performed using three phantoms each consisting a 30 mm diameter homogeneous PMMA cylinder...