- Reproductive Physiology in Livestock
- Genetic and phenotypic traits in livestock
- Ruminant Nutrition and Digestive Physiology
- Effects of Environmental Stressors on Livestock
- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Pregnancy and preeclampsia studies
- Pharmacological Effects and Assays
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Platelet Disorders and Treatments
- Rangeland and Wildlife Management
- Gestational Diabetes Research and Management
- Pasture and Agricultural Systems
- Rangeland Management and Livestock Ecology
- Neonatal Respiratory Health Research
- Meat and Animal Product Quality
- Agriculture and Farm Safety
- Wildlife Ecology and Conservation
- Blood groups and transfusion
- Hemophilia Treatment and Research
- Agriculture Sustainability and Environmental Impact
- Blood Coagulation and Thrombosis Mechanisms
- Muscle metabolism and nutrition
- Lipid metabolism and biosynthesis
- Turfgrass Adaptation and Management
University of Nebraska–Lincoln
2018-2024
University of Arizona
2023-2024
New Mexico State University
2016-2020
Universidad de Costa Rica
2010
Conquest Hospital
2005-2007
St Thomas' Hospital
1988-2006
Chelsea and Westminster Hospital
1988
Virtual fence (VF) is the use of a global positioning system (GPS) to dictate where on landscape livestock can graze without relying traditional physical such as barbed wire. The recent acceleration in development and adoption VF technology for grazing management has been characterized by evolution divergent terminology. Different research commercial entities have adopted terms definitions independently. Some are inherently problematic, while others more aligned, simple fact that differences...
Thrombocytopenia is common in pregnancy and diverse etiology. Immune thrombocytopenic purpura (ITP) may affect both mother the newborn. Gestational (incidental) thrombocytopenia an otherwise fit woman, at term most frequent type of poses no clinical consequences for or infant. We report six women who presented with severe during pregnancy. Five were treated late pregnancy, either intravenous immunoglobulin (IVIg), IVIg followed by steroids. There was response, four received a platelet...
Intrauterine stress impairs growth and metabolism in the fetus offspring. We recently found that sustained maternofetal inflammation resulted intrauterine growth-restricted (MI-IUGR) fetuses with asymmetric body composition, impaired muscle glucose metabolism, β-cell dysfunction near term. These also exhibited heightened inflammatory tone, which we postulated was a fetal programming mechanism for IUGR phenotype. Thus, objective of this study to determine whether poor persisted MI-IUGR lambs...
Summary Four patients with severe haemophilia A and one patient Christmas disease developed immune thrombocytopenia (platelet count < 20 × 10 9 /1). All five were HIV‐antibody positive was HIV‐antigen positive. treated initially prednisolone, but only a transient platelet response in three no the fourth. high dose intravenous immunoglobulin (0.4 g/kg daily for 5 d) resulting rise all cases (range 138–300 x /1) then proceeded to splenectomy. Three remain complete remission after 6–14...
Stress-induced fetal programming diminishes β2 adrenergic tone, which coincides with intrauterine growth restriction (IUGR) and lifelong metabolic dysfunction. We determined if stimulating activity in IUGR-born lambs would improve outcomes. IUGR that received daily injections of saline or the agonist clenbuterol from birth to 60 days were compared controls pair-fed thermoneutral pregnancies. As juveniles, exhibited systemic inflammation robust dysfunction, including greater (p < 0.05)...
Primary polycythaemia (PP), idiopathic myelofibrosis (MF), essential thrombocythaemia (ET) and chronic granulocytic or myeloid leukaemia (CGL) are clonal disorders of the pluripotent haemopoietic stem cells. We have studied granulocyte, megakaryocyte erythroid progenitors from peripheral blood 7 patients with PP, 9 ET, 19 MF 6 CGL in order to characterise similarities differences at committed progenitor cell level. Spontaneous megakaryocytic erythrocytic growth was characteristic MF, PP ET...
The simultaneous occurrence of Hodgkin lymphoma with a variety B-cell Non-Hodgkin lymphomas (composite lymphoma) has been described. We report the first case composite and splenic marginal zone occurring simultaneously in same lymph node 64-year-old man who presented cervical axillary lymphadenopathy massive splenomegaly. He had peripheral blood lymphocytosis bone marrow infiltrated by small lymphocytes. However, biopsy showed classic lymphoma. His splenomegaly only partial response to six...
Background: Intrauterine growth restriction ( IUGR ) is associated with reduced β2 adrenergic sensitivity, which contributes to poor postnatal muscle growth. The objective of this study was determine if stimulating activity would rescue deficits in growth, body composition, and indicators metabolic homeostasis offspring. Methods: Time-mated ewes were housed at 40°C from day 40 95 gestation produce lambs. From birth, lambs received daily IM injections 0.8 μg/kg clenbuterol HCl IUGR+CLEN ; n =...
Abstract Poor udder and teat confirmation decreases profitability due to decreased calf weaning weight, increased incidence of mastitis labor, cow lifetime productivity. Therefore, the objective this retrospective study was evaluate effect beef score on performance pre- postweaning progeny performance. In a 5-yr study, crossbred cows at Gudmundsen Sandhills Laboratory, Whitman, NE, were assigned an each year calving, from 1 5, using combination score. Cows grouped by scores classified as...
In humans and animals, intrauterine growth restriction (IUGR) results from fetal programming responses to poor conditions. Chronic hypoxemia elevates circulating catecholamines, which reduces skeletal muscle β2 adrenoceptor content contributes metabolic pathologies in IUGR-born offspring. Our objective was determine whether intermittent maternofetal oxygenation during late gestation would improve neonatal glucose metabolism lambs. Pregnant ewes were housed at 40 °C the 40th 95th day of...