A5052856934- Plant Stress Responses and Tolerance
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Potato Plant Research
- Antimicrobial Peptides and Activities
- Probiotics and Fermented Foods
- Plant Gene Expression Analysis
- Migraine and Headache Studies
- Gut microbiota and health
- Plant Reproductive Biology
- Protein Hydrolysis and Bioactive Peptides
- Plant Virus Research Studies
- Plant Physiology and Cultivation Studies
- Energy, Environment, Economic Growth
- Efficiency Analysis Using DEA
- Insect Utilization and Effects
- Healthcare and Venom Research
- Plant Genetic and Mutation Studies
- Plant Pathogens and Resistance
- Pain Mechanisms and Treatments
- Neuropeptides and Animal Physiology
- Environmental Impact and Sustainability
- Immune Response and Inflammation
- Microbial Natural Products and Biosynthesis
- Garlic and Onion Studies
The First People's Hospital of Guiyang
2025
Capital Medical University
2020-2023
Beijing Tongren Hospital
2020-2023
Zhongnan University of Economics and Law
2023
China Agricultural University
2007-2022
Shanxi University of Traditional Chinese Medicine
2017-2022
Shanxi Agricultural University
2021-2022
Beijing University of Agriculture
2016-2022
Guizhou Academy of Agricultural Sciences
2021-2022
Rice Research Institute
2021-2022
Intracranial headaches such as migraine are thought to result from activation of sensory trigeminal pain neurons that supply intracranial blood vessels and the meninges, also known meningeal nociceptors. Although mechanism underlying triggering is not completely understood, our previous work indicates local inflammatory dural mast cells can provoke a persistent sensitization Given potential importance it important understand which cell-derived mediators interact with nociceptors promote...
The proinflammatory cytokine TNF-α has been shown to promote activation and sensitization of primary afferent nociceptors. downstream signaling processes that play a role in promoting this neuronal response remain however controversial. Increased plasma levels during migraine attacks suggest local interaction between intracranial meningeal nociceptors plays the headache. Here, using vivo single unit recording trigeminal ganglia anesthetized rats, we show action promotes delayed mechanical...
Abstract The SNAT enzyme participates in the biosynthesis of melatonin, which is reported to regulate thermotolerance many plants. However, mechanistic basis this regulation remains unclear. In study, we identified SlSNAT gene, responsible for melatonin tomato. expression levels were 3- and 5-fold higher overexpression lines OX-2 OX-6, respectively. 4-fold than those wild type. decreased by 50% when was downregulated 40%. Overexpression tomato plants provided significantly enhanced with...
Abstract Jasmonic acid (JA) is a key regulator of plant defense responses. Although the transcription factor MYC2, master JA signaling pathway, orchestrates hierarchical transcriptional cascade that regulates responses, only few regulators involved in this have been described. Here, we identified basic helix‐loop‐helix (bHLH) gene tomato ( Solanum lycopersicum ), METHYL JASMONATE MeJA ) ‐INDUCED GENE SlJIG expression which was strongly induced by treatment. Genetic and molecular biology...
Abstract Initiation and progression of leaf senescence are triggered by various environmental stressors phytohormones. Jasmonic acid (JA) darkness accelerate in plants. However, the mechanisms that integrate these two factors to initiate regulate have not been identified. Here, we report a transcriptional regulatory module centred on novel tomato WRKY transcription factor, SlWRKY37, responsible for both JA- dark-induced senescence. The expression together with SlMYC2, encoding master factor...
Abstract Improving plant water‐use efficiency (WUE) is important to survival and crop yield in the context of water limitation. In this study, SlTLFP8 (Tubby‐like F‐box protein 8) was identified as an osmotic‐induced gene tomato. Transgenic tomato with up‐regulated expression showed enhanced water‐deficient resistance, whereas knockout mutants generated by CRISPR/Cas9 were more sensitive deficit. overexpression significantly WUE suppressing transpiration under both water‐sufficient...
Background: Peripheral nociceptive action of the proinflammatory cytokines IL-1β and IL-6 has been implicated in pathogenesis numerous pain syndromes. An increase level these jugular venous blood reported during migraine attacks, suggesting their potential involvement mediating intracranial headache migraine. Methods: In this work we examined, using vivo single-unit recording meningeal nociceptors trigeminal ganglion anesthetized rats, whether peripheral actions can promote activation...
With increasingly serious eye exposure to light stresses, such as light-emitting diodes, computers, and widescreen mobile phones, efficient natural compounds for preventing visible light-induced retinal damages are becoming compelling needs in the modern society. Fucoxanthin, main absorption system marine algae, may possess an outstanding bioactivity vision protection because of its filtration blue excellent antioxidative activity. In this work, both vitro vivo simulated damage models were...
Pentatricopeptide repeat (PPR) proteins play important roles in the post-transcriptional modification of organellar RNAs plants. However, function most PPR remains unknown. Here, we characterized rice (Oryza sativa L.) chlorophyll deficient 4 (cde4) mutant which exhibits an albino phenotype during early leaf development, with decreased contents and abnormal chloroplasts at low-temperature (20°C). Positional cloning revealed that CDE4 encodes a P-type protein localized chloroplasts. In cde4...
Abstract Migraine attacks associated with throbbing (manifestation of peripheral sensitization) and cutaneous allodynia central are readily terminated by intravenous administration a non‐selective cyclooxygenase (COX) inhibitor. Evidence that sensitization rat trigeminovascular neurons was also in vivo COX inhibition has led us to propose inhibitors may act centrally the dorsal horn. In present study, we examined whether can suppress meningeal nociceptors. Using single‐unit recording...
The lipid peroxidation of unsaturated fatty acids (UFAs) in the retina not only threatens visual cells but also affects physiological health retina. In this work, potential damages caused by daily visible light exposure on retinal UFAs were evaluated via a simulated vitro model. At same time, benefits dietary supplementation blueberries to eyes assessed. After prolonged exposure, occurred for both docosahexaenoic and arachidonic (DHA AA, respectively). oxidized presented obvious cytotoxicity...
Nine new sesquiterpene quinones/hydroquinones (1-7, 10, and 12), three solvent-generated artifacts (8, 9, 11), known compounds, 5-epi-smenospongine (13), smenospongine (14), smenospongiadine (15), were isolated from the marine sponge Spongia pertusa Esper. The planar structures of compounds elucidated on basis spectroscopic analyses. Their absolute configurations determined by comparison between calculated experimental ECD spectra. In cytotoxicity bioassay, 13-15 exhibited activities against...
<title>Abstract</title> <bold>Objective </bold>To analyze the importance ranking of influencing factors postoperative complications in patients with ureteral calculi using Logistic regression and random forest algorithm, to construct verify prediction model. <bold>Methods </bold>Clinical information 254 who received surgical treatment our hospital from January 2021 December 2023 was collected as variables, including age, gender, diameter, location, type, preoperative urine routine, etc....
Herein, we identified the tomato SlMYB102 gene as a MYB family transcription factor of R2R3-MYB subfamily. We additionally determined that promoter region contains photoresponsive, abiotic stress-responsive, and hormone-responsive regulatory elements, detected higher expression in reproductive organs than vegetative organs, with being highest ripe fruits roots. was also shown to be cold-inducible. The protein encoded by localized nucleus wherein it found mediate transcriptional activation...
This study investigates the simultaneous effect of acrylamide (ACR) and high-fat-intake on apoptosis in testis cells, also expression activity caspase-3. Seventy-two male Kunming mice were divided into two blocks fed with a high-fat diet (crude fat 21.5%) or basic 4.4%), respectively; animals each block exposed to ACR at dose 20 mg/kgbw•d 40 as treated groups normal saline control. Germ cells prepared from stained Hoechst dye 33258 paraffin wax sections suffered TUNEL process. Expression...