A5060911982- Infant Nutrition and Health
- Child Nutrition and Water Access
- Eicosanoids and Hypertension Pharmacology
- Enterobacteriaceae and Cronobacter Research
- Infant Health and Development
- Child Nutrition and Feeding Issues
- Sports Analytics and Performance
- Intestinal Malrotation and Obstruction Disorders
- Asthma and respiratory diseases
- Case Reports on Hematomas
- Intraperitoneal and Appendiceal Malignancies
- Pediatric Hepatobiliary Diseases and Treatments
- Viral gastroenteritis research and epidemiology
- Helicobacter pylori-related gastroenterology studies
- Clinical Nutrition and Gastroenterology
- Biliary and Gastrointestinal Fistulas
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Sports, Gender, and Society
- Inflammatory mediators and NSAID effects
- Birth, Development, and Health
- Hormonal Regulation and Hypertension
- Digestive system and related health
- Breastfeeding Practices and Influences
- Metabolism and Genetic Disorders
- Neonatal Respiratory Health Research
University of Southern California
2015-2019
Children's Hospital of Los Angeles
2015-2019
The use of lactobacilli in prevention necrotizing enterocolitis (NEC) is hampered by insufficient knowledge about optimal species/strains and effects on intestinal bacterial populations. We therefore sought to identify naturally occurring postnatal rats examine their ability colonize the neonatal intestine protect from NEC. L. murinus, acidophilus, johnsonii were found 42, 20, 1 out 51 4-day old rats, respectively. Higher proportion murinus microbiota correlated with lower NEC scores....
Necrotizing enterocolitis (NEC) is a significant cause of morbidity and mortality in premature infants; yet its pathogenesis remains poorly understood. To evaluate the role intestinal bacteria protection against NEC, we assessed ability naturally occurring colonizer E. coli EC25 to influence composition microbiota NEC pathology neonatal rat model. Experimental was induced rats by formula feeding/hypoxia, graded histologically. Bacterial populations were characterized plating on blood agar,...
High levels of PGE2 have been implicated in the pathogenesis intestinal inflammatory disorders such as necrotizing enterocolitis (NEC) and peritonitis. However, has a paradoxical effect: its low promote homeostasis, whereas high may contribute to pathology. These concentration-dependent effects are mediated by four receptors, EP1-EP4. In this study, we evaluate effect blockade affinity pro-inflammatory receptors EP1 EP2 on expression COX-2, rate-limiting enzyme biosynthesis, gut barrier...