A5046828820- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Transplantation: Methods and Outcomes
- Esophageal and GI Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastroesophageal reflux and treatments
- Gallbladder and Bile Duct Disorders
- Drug-Induced Hepatotoxicity and Protection
- Liver physiology and pathology
- Eosinophilic Esophagitis
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Helminth infection and control
- Nutrition and Health in Aging
- Airway Management and Intubation Techniques
- Bariatric Surgery and Outcomes
- Sarcoma Diagnosis and Treatment
- Peroxisome Proliferator-Activated Receptors
- Health, Nursing, Elderly Care
- Abdominal Surgery and Complications
- Diabetes Treatment and Management
- Advanced Battery Technologies Research
- Parasites and Host Interactions
Hospital Israelita Albert Einstein
2020-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2022
Queen Elizabeth Hospital Birmingham
2017-2021
University Hospitals Birmingham NHS Foundation Trust
2018-2019
Queen Elizabeth Hospital
2018-2019
Queen Elizabeth University Hospital
2019
National Health Service
2019
Universidade Estadual de Campinas (UNICAMP)
2014-2015
Strategies to increase the use of steatotic donor livers are required tackle mortality on transplant waiting list. We aimed test efficacy pharmacological enhancement lipid metabolism human during ex situ normothermic machine perfusion promote defatting and improve functional recovery organs. Because steatosis, 10 were discarded allocated either a group that had perfusate supplemented with combination drugs enhance or control received fluid vehicle only. Steatosis was assessed using tissue...
Retransplantation candidates are disadvantaged owing to lack of good-quality liver grafts. Strategies that can facilitate transplantation suboptimal grafts into retransplant require investigation. The aim was determine whether late retransplantation be performed safely with grafts, following normothermic machine perfusion.A prospectively enrolled group patients who required received a graft preserved via perfusion. This compared both historical and contemporaneous cohorts patient by cold...
Loco-regional complications of transarterial chemoembolization (TACE) may adversely affect technical aspects the liver transplantation (LT). This study reviewed impact those on postoperative outcomes encompassing implications graft selection.A retrospective, propensity score matching (1:1) analysis accounting for donor and recipient confounders was performed a dataset patients undergoing LT hepatocellular carcinoma. Outcomes who had TACE (TACE-group) were compared with did not...
Introduction Pharmacological defatting of rat hepatocytes and hepatoma cell lines suggests that the same method could be used to ameliorate macrovesicular steatosis in moderate severely fatty livers. However there is no data assessing effects those drugs on primary human liver cells. We aimed determine effectiveness a pharmacological cocktail reducing vitro lipid content (PHH). In addition we sought cytotoxicity towards non-parenchymal Methods Steatosis was induced PHH by supplementation...
Parameters of retrieval surgery are meticulously documented in the United Kingdom, where up to 40% livers donation after circulatory death (DCD) donations. This retrospective analysis focuses on outcomes transplantation DCD livers, retrieved by different UK centers between 2011 and 2016. Donor recipient risk factors donor technique were assessed. A total 236 from 9 with a median score 5 (low risk) 7 points (high compared. The majority used University Wisconsin solution for aortic flush...
Normothermic machine perfusion (NMP) of liver grafts is increasingly being incorporated in clinical practice. Current evidence has shown NMP plays a role reconditioning the synthetic and energy capabilities grafts. Intraoperative coagulation profile surrogate graft quality preservation status; however, to date this aspect not been documented.The transplantation recipients who received QEHB between 2013 2016 were compared terms intraoperative thromboelastography characteristics (R time, K...
Asthma, laryngitis and chronic cough are atypical symptoms of the gastroesophageal reflux disease.To analyze efficacy laparoscopic surgery in remission extra-esophageal patients with reflux, related to asthma.Were reviewed medical records 400 disease submitted Nissen fundoplication from 1994 2006, identified 30 asthma. The variables considered were: gender, age, (heartburn, acid dysphagia), time disease, treatment proton pump inhibitor, use specific medications, evolution, number attacks...
This case report describes the longest reported HOPE treatment ever for an extended criteria donor organ in donation after brain death performed to enable transplantation of a surgically complex retransplant case. Although further evidence is required, may facilitate liver retransplantation, expanding pool and reducing time constraints on operation.
Intrahepatic caval leiomyosarcomas are rare tumors with limited therapeutic options as patients the disease not eligible for liver transplantation from deceased-donor pool. Advances in surgical techniques gained split and domino transplant procedures can be applied to resection of advanced involving hepatocaval confluence. Here, we describe case a 58-year-old white female who presented visible abdominal wall collaterals palpable right subcostal tumor. Imaging revealed 5.7 × 11-cm...
Unplanned hospital readmission after pancreaticoduodenectomy (PD) is usually due to surgical complications and has significant clinical economic impact. This study developed a risk score predict 30-day PD.Patients undergoing PD between 2009 2016 were reviewed from prospective database. Predictors of identified using multivariable logistic regression model, which points-based scoring system was derived.81 518 patients (15.6%) readmitted within 30 days. History cardiac disease ([odds ratio] OR...
Gastric strongyloidiasis and megaduodenum are rare diseases. Gastrointestinal (GI) has many clinical features. One of them is megaduodenum. We describe a case 32-years-old man who come to us from an endemic area for Strongyloides stercoralis. He had diagnosed in his childhood. submitted him two surgeries. recovered just after the second surgery, Roux-en-Y partial gastrectomy. After that, follow-up was uneventful patient gained 10kg weight. Histopathology confirmed gastric strongyloidiasis....
Despite its association with higher postoperative morbidity and mortality, the use of extended criteria donor (ECD) livers for transplantation has increased globally due to high demand procedure.To investigate prevalence ECD in donation after brain death (DBD) impact on organ acceptance transplantation.Retrospective analysis DBD offers liver between 2017 2020 a high-volume transplant centre. The incidence Eurotransplant risk factors define an (ET-ECD) among donors likelihood over years were...
Transarterial chemoembolization (TACE) in patients with hepatocellular cancer (HCC) on the waiting list for liver transplantation may be associated an increased risk hepatic artery complications. The present study aims to assess for, primarily, intraoperative technical problems and, secondarily, postoperative complications encountered who received TACE before transplantation.Available data from HCC recipients across six European centres January 2007 December 2018 were analysed a 1 :...