A5103208764- Bacterial Identification and Susceptibility Testing
- Clinical Laboratory Practices and Quality Control
- Antimicrobial Resistance in Staphylococcus
- Infection Control in Healthcare
- Streptococcal Infections and Treatments
- Quality and Safety in Healthcare
- Yersinia bacterium, plague, ectoparasites research
- Clostridium difficile and Clostridium perfringens research
- Reproductive tract infections research
- Bacillus and Francisella bacterial research
- Infection Control and Ventilation
- Pharmacological Effects of Natural Compounds
- Urinary Tract Infections Management
- Cervical Cancer and HPV Research
- Antifungal resistance and susceptibility
- Vibrio bacteria research studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Plant-based Medicinal Research
- Antibiotic Resistance in Bacteria
- Health and Medical Research Impacts
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Clinical Reasoning and Diagnostic Skills
- Salmonella and Campylobacter epidemiology
- Air Quality and Health Impacts
- Meta-analysis and systematic reviews
University of British Columbia
2008-2024
UK Health Security Agency
2022
University of Bristol
2019
University of Nottingham
2019
Ministry of the Environment, Conservation and Parks
2019
Obong University
2016
Sonoma State University
1987-2015
Vancouver General Hospital
2010-2014
University of Dundee
2009
Vancouver Coastal Health
2006
Entomology is key to understanding terrestrial and freshwater ecosystems at a time of unprecedented anthropogenic environmental change offers substantial untapped potential benefit humanity in variety ways, from improving agricultural practices managing vector-borne diseases inspiring technological advances.We identified high priority challenges for entomology using an inclusive, open, democratic four-stage prioritisation approach, conducted among the membership affiliates (hereafter...
We examined Tenckhoff peritoneal catheters by scanning and transmission electron microscopy to study the morphology of bacterial adherence. Two were removed from uninfected patients, three patients with exit site infections, four peritonitis, one a patient both infection peritonitis. Infecting organisms included Staphylococcus aureus each Enterobacter sp., epidermidis, Achromobacter xylosoxidans, Serratia Klebsiella Candida albicans. Considerable morphological variation in adherence dialysis...
Escherichia coli isolated from cases of bacteremia and a variety urinary tract infections were characterized according to serotype (O:H antigenicity), K type (possession K1, K2, K3, K12, or K13), hemagglutination (HA) type, production beta-hemolysin. Results obtained with the infection isolates similar except for more hemolytic urine than blood (42 versus 29%) K1+ (50 29%). A close correlation was found between Ha VI (production fimbriae which mediate mannose-resistant HA human African green...
A commercially available latex agglutination test for Clostridium difficile was compared with a cell culture cytotoxin assay and bacteriological the laboratory diagnosis of C. difficile-associated diarrhea colitis (CAD). Stool specimens from 626 patients were tested by three methods, 118 (19%) positive at least one methods. The results tests agreed in 88% tested, overall, but they only 34% specimens. Ninety-three evaluated to assess significance negative each assay. Of 40 found have CAD, 70%...
During the 42-month period from June 1982 through December 1985, 215 fecal specimens 171 patients were found to be positive for yersiniae by using a combination of CIN agar and cold enrichment. Isolates tested markers virulence including carriage plasmid 42 megadaltons in size, calcium dependence, autoagglutination, Congo red uptake, pyrazinamidase activity, fermentation salicin, hydrolysis esculin. The results correlated symptoms patients. A total 80 Yersinia enterocolitica 52 Y....
Journal Article Xanthomonas maltophilia Misidentified as Pseudomonas cepacia in Cultures of Sputum from Patients with Cystic Fibrosis: A Diagnostic Pitfall Major Clinical Implications Get access David R. Burdge, Burdge Divisions Infectious Disease and Medical Microbiology, University Hospital British Columbia; Canadian Repository Laboratory the Department Pediatrics, Microbiology Laboratory, Hospital; Division & Immunological Diseases, Columbia's Children's Columbia, Vancouver, Canada...
Background The safety and efficacy of Ciprodex® has been demonstrated for treatment chronic suppurative otitis media (CSOM). However, symptoms fail to resolve in 9-15% patients. objective this study is evaluate the N-acetylcysteine (NAC) on S. aureus, planktonic sessile (biofilm forming) P. aeruginosa vitro using clinical isolates from patients with CSOM. Methods 1) Stability was assessed liquid chromatography-mass spectrometry each component a prepared mixture NAC over 15 days. Sterility by...
Two Canadian urban areas received travelers with severe acute respiratory syndrome (SARS) before the World Health Organization issued its alert. By July 2003, Vancouver had identified 5 cases (4 imported); Toronto reported 247 (3 imported) and 43 deaths. Baseline preparedness for pandemic threats may account absence of sustained transmission fewer SARS in Vancouver.
The lack of an adequate typing system hampers our understanding the epidemiology infections caused by coagulase-negative staphylococci (CoNS). CoNS have become recognized as important nosocomial pathogens and principal cause associated with invasive devices. Sensitive, specific, convenient methods are needed to evaluate whether implementing infection control guidelines reduces risk from other pathogens. Microbial Identification System (MIDI) (Microbial ID Inc., Newark, Del.), a semiautomated...
The increasing spread and rising profile of publicly engaged research in the UK has been accompanied by emergence a new, specialized professional services role embedded within project teams. With this mind, Public Engagement Professionals University Research Network convened survey workshop 2017 to critically examine skills experiences individuals administrative roles such projects. This paper argues that is highly skilled blurs boundaries between academic, administrator engagement...
This article reports on the findings of 12,278 laboratory related safety events that were reported through British Columbia Patient Safety & Learning System Incident Reporting System.The collected from 75 hospital-based laboratories over a 33-month period and represent approximately 4.9% all incidents reported.Consistent with previous studies 76% occurred during pre-analytic phase cycle, twice as many associated collection problems clerical problems. Eighteen percent post-analytic reporting...
In response to the coronavirus pandemic (COVID-19) and scale up of diagnostic testing, Canadian Microbiology Proficiency Testing program created a new proficiency testing (PT) for molecular antigen detection SARS-CoV-2. The was geared point care (POCT) sites located in each eight provincial Health Authorities across British Columbia, Canada, with intention monitor quality. PT consisted 6 shipments year, containing set 4 samples either positive SARS-CoV-2 virus or negative. began initial 23...
Abstract Aim To determine the cost‐effectiveness of all options for self‐monitoring blood glucose funded by National Health Service, providing guidance disinvestment and testing hypothesis that advanced meter features may justify higher prices. Methods Using data from Social Care Information Centre concerning 8 340 700 glucose‐related prescriptions during 2013/2014, we conducted a cost‐minimization analysis, considering both strip lancet costs, including clinically equivalent technologies...
Competent leadership and management are imperative for delivering quality laboratory services; however, few managers receive job-specific training in organisational leadership.To develop evaluate participants' competencies as measured through learner improvement assessments.This professional development programme employed a mentored, blended learning approach, utilising in-person didactic online training, with the practical application of capstone project laboratories. Programme impact was...
The pKa of (Asp158)-CO2H papain (EC 3.4.22.2) was determined as 2.8 by using 4-chloro-7-nitrobenzofurazan (Nbf-Cl) a reactivity probe targeted on the thiolate anion component Cys25/His159 nucleophilic-acid/base motif catalytic site. possibility Nbf-Cl for this purpose established modelling papain-Nbf-Cl Meisenheimer intermediate QUANTA/CHARMM and performing molecular orbital calculations with MOPAC interfaced Cerius 2. A pH-dependent stopped-flow kinetic study reaction that striking rate...