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Joseph N. Shohdy

ORCID: 0000-0001-7066-2219
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About
Contact & Profiles
A5049367425
Research Areas
  • Advanced Drug Delivery Systems
  • Drug Solubulity and Delivery Systems
  • Advancements in Transdermal Drug Delivery
  • HIV/AIDS drug development and treatment

Misr University for Science and Technology
 2022

 Chitosan decorated nanostructurated lipid carriers for augmented oral bioavailability of velpatasvir; D- optimal optimization, in silico, in vitro, ex vivo and in vivo studies
OPENALEX - Publications 
Menna M. Abdellatif Joseph N. Shohdy Doaa Ahmed El-Setouhy Maha M. Abdel‐Fattah Basant F. Rofaeil and 2 more Marianne J. Naguib Mohamed A. El-Nabarawi

10.1016/j.jddst.2025.106703 article EN Journal of Drug Delivery Science and Technology 2025-02-01
 Compritol-Based Nanostrucutured Lipid Carriers (NLCs) for Augmentation of Zolmitriptan Bioavailability via the Transdermal Route: In Vitro Optimization, Ex Vivo Permeation, In Vivo Pharmacokinetic Study
OPENALEX - Publications 
Doaa H. Hassan Joseph N. Shohdy Doaa Ahmed El-Setouhy Mohamed A. El-Nabarawi Marianne J. Naguib

Migraine is a severe neurovascular disease manifested mainly as unilateral throbbing headaches. Triptans are agonists for serotonin receptors. Zolmitriptan (ZMP) biopharmaceutics classification system (BCS) class III medication with an absolute oral bioavailability of less than 40%. As result, our research intended to increase ZMP by developing transdermal nanostructured lipid carriers (NLCs). NLCs were prepared utilizing combination hot melt emulsification and high-speed stirring in 32 full...

10.3390/pharmaceutics14071484 article EN cc-by Pharmaceutics 2022-07-18
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